ChemicalBook > CAS DataBase List > AC-IETD-AFC
AC-IETD-AFC
- Product Name
- AC-IETD-AFC
- CAS No.
- 211990-57-7
- Chemical Name
- AC-IETD-AFC
- Synonyms
- AC-IETD-AFC;AC-ILE-GLU-THR-ASP-AFC;Caspase 8 Substrate 1f;CGUOWXRXLQXOKO-FCQBACSVSA-N;M.W. 729.66 C31H38F3N5O12;CASPASE-8 FLUOROGENIC SUBSTRATE;CASPASE 8 SUBSTRATE 1F, FLUOROGENIC;GRANZYME B SUBSTRATE I, COLORIMETRIC;AC-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;N-ACETYL-ILE-GLU-THR-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN)
- CBNumber
- CB1395556
- Molecular Formula
- C31H38F3N5O12
- Formula Weight
- 729.65
- MOL File
- 211990-57-7.mol
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AC-IETD-AFC Property
- Boiling point:
- 1113.8±65.0 °C(Predicted)
- Density
- 1.437±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO
- pka
- 4.09±0.10(Predicted)
- form
- Lyophilized powder
- color
- White to off-white
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N-Bromosuccinimide Price
Alfa Aesar
- Product number
- J64258
- Product name
- N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin
- Packaging
- 5mg
- Price
- $161
- Updated
- 2021/12/16
Cayman Chemical
- Product number
- 17480
- Product name
- Ac-IETD-AFC
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17480
- Product name
- Ac-IETD-AFC
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17480
- Product name
- Ac-IETD-AFC
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $321
- Updated
- 2024/03/01
TRC
- Product number
- A795613
- Product name
- Ac-IETD-AFC
- Packaging
- 5mg
- Price
- $145
- Updated
- 2021/12/16
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AC-IETD-AFC Chemical Properties,Usage,Production
Uses
N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin is a fluorogenic substrate for caspases -6, -8, and -10. The IETD sequence is based on the procaspase-3 cleavage site. Residues 172-175 of procaspase-3 are cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3.
Uses
Ac-IETD-AFC is a fluorogenic substrate for caspase-8/caspase-3 processing enzyme and granzyme B. It is also a substrate for caspase-10. The IETD sequence is based on caspase-3 proenzyme cleavage site.
AC-IETD-AFC Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from AC-IETD-AFC manufacturers
Career Henan Chemical Co
- Product
- AC-IETD-AFC 211990-57-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-03-05