3-(TRIMETHYLSILYL)PROPIOLIC ACID

Product Name: 3-(TRIMETHYLSILYL)PROPIOLIC ACID
CAS No.: 5683-31-8
Chemical Name: 3-(TRIMETHYLSILYL)PROPIOLIC ACID
Synonyms: DKFELEX0274;3-(Trimethylsi;TIMTEC-BB SBB009048;Trimethylsilanyl-propynoic acid;3-(TRIMETHYLSILYL)PROPYNOIC ACID;3-(TRIMETHYLSILYL)PROPIOLIC ACID;3-trimethylsilyl-2-propynoic acid;3-(Trimethylsilyl)propargylic Acid;3-(trimethylsilyl)prop-2-ynoic acid;3-(Trimethylsilyl)propynoic acid 98%
CBNumber: CB1397217
Molecular Formula: C6H10O2Si
Formula Weight: 142.23
MOL File: 5683-31-8.mol

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3-(TRIMETHYLSILYL)PROPIOLIC ACID Property

Melting point:: 47-49 °C (lit.)
Boiling point:: 105-110 °C/10 mmHg (lit.)
Density: 1.006±0.06 g/cm3(Predicted)
Flash point:: 205 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Soluble in methanol.
form: solid
pka: 1.88±0.10(Predicted)
color: White to Almost white
Hydrolytic Sensitivity: 4: no reaction with water under neutral conditions
BRN: 1755674
InChI: InChI=1S/C6H10O2Si/c1-9(2,3)5-4-6(7)8/h1-3H3,(H,7,8)
InChIKey: IPEATTYBFBRNEB-UHFFFAOYSA-N
SMILES: C(O)(=O)C#C[Si](C)(C)C
CAS DataBase Reference: 5683-31-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 1-10
TSCA: No
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 403482
Product name: 3-(Trimethylsilyl)propynoic acid
Purity: 98%
Packaging: 1g
Price: $73.4
Updated: 2025/07/31

Sigma-Aldrich

Product number: 403482
Product name: 3-(Trimethylsilyl)propynoic acid
Purity: 98%
Packaging: 5g
Price: $215
Updated: 2025/07/31

TCI Chemical

Product number: T3040
Product name: 3-(Trimethylsilyl)propiolic Acid
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $374
Updated: 2025/07/31

TCI Chemical

Product number: T3040
Product name: 3-(Trimethylsilyl)propiolic Acid
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $1495
Updated: 2025/07/31

Activate Scientific

Product number: AS118457
Product name: 3-(Trimethylsilyl)propiolic Acid
Purity: 97+%
Packaging: 5G
Price: $354
Updated: 2021/12/16

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3-(TRIMETHYLSILYL)PROPIOLIC ACID Chemical Properties,Usage,Production

Uses

3-(Trimethylsilyl)propiolic acid may be used in the regioselective preparation of 1,5-trisubstituted 1H-1,2,3-triazoles. It is also used as pharmaceutical intermediate.

Synthesis

2975-46-4

5683-31-8

The general procedure for the synthesis of 3-(trimethylsilyl)propynoic acid from 3-trimethylsilylpropynal was as follows: in a reaction test tube, trans-2-decene (167 mg, 1.0 mmol) was added to a mixture containing Fe(NO3)3-9H2O (4.1 mg, 0.010 mmol) and CF3COONa (28 mg, 0.20 mmol) in an EtOAc (0.50 mL) in suspension. An O2 balloon (1 atm) was attached to the top of the test tube to displace the internal atmosphere with O2. After the reaction mixture was stirred at 25 °C for 16 h, EtOAc (3 mL) and 1 M HCl aqueous solution (1 mL) were added and the resulting two-phase mixture was stirred for 1 min. The organic phase was separated and the aqueous phase was extracted with EtOAc (3 mL × 2). After combining the organic phases, quantitative biphenyl (as an internal standard for NMR analysis) was added. The conversion of the substrate and the yield of the product were determined by NMR analysis (400 MHz, CDCl3, 25 °C). Products were identified by comparing the NMR signals of real samples. Each reaction was repeated twice to ensure reproducible results.

References

[1] Chemistry Letters, 2016, vol. 45, # 2, p. 188 - 190

3-(TRIMETHYLSILYL)PROPIOLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-(TRIMETHYLSILYL)PROPIOLIC ACID manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 3-(TRIMETHYLSILYL)PROPIOLIC ACID 5683-31-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-04

Career Henan Chemical Co

Product: 3-(TRIMETHYLSILYL)PROPIOLIC ACID 5683-31-8
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: as request
Release date: 2018-12-24

5683-31-8, 3-(TRIMETHYLSILYL)PROPIOLIC ACIDRelated Search:

Propiolic Acid Propyne 3-(TRIMETHYLSILYL)PROPIOLIC ACID 3-TRIMETHYLSILYL-2-PROPYN-1-OL (trimethylsilyl)propiolic acid methyl ester 3-TRIMETHYLSILYLPROPYNAL TRIMETHYLSILYL(TRIMETHYLSILYL)PROPYNOATE ETHYL 3-(TRIMETHYLSILYL)PROPIOLATE

3-(TRIMETHYLSILYL)PROPIOLIC ACID

3-(TRIMETHYLSILYL)PROPYNOIC ACID

TIMTEC-BB SBB009048

3-(Trimethylsilyl)propynoic acid,3-(Trimethylsilyl)propiolic acid

3-(TRIMETHYLSILYL)PROPIOLIC ACID 95%

3-(Trimethylsilyl)propynoic acid 98%

3-(Trimethylsi

3-trimethylsilyl-2-propynoic acid

Trimethylsilanyl-propynoic acid

3-(trimethylsilyl)prop-2-ynoic acid

2-Propynoic acid, 3-(trimethylsilyl)-

3-(Trimethylsilyl)propargylic Acid

DKFELEX0274

5683-31-8

CH33SiCCCOOH

C6H10O2Si

CH33SiC8801CCO2H

CH33SiCCCO2H

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