3,3'-Dimethoxybenzidine dihydrochloride Property

Melting point:

268 °C

Flash point:

206℃

storage temp. 

2-8°C

solubility 

H2O: soluble25mg/mL

form 

tablet

color 

Light beige to purple-gray

PH

1.7 at 20℃ and 100g/L

Water Solubility 

1-5 g/100 mL at 20 ºC

BRN 

3917996

InChIKey

UXTIAFYTYOEQHV-UHFFFAOYSA-N

CAS DataBase Reference

20325-40-0(CAS DataBase Reference)

EPA Substance Registry System

3,3'-Dimethoxybenzidine dihydrochloride (20325-40-0)

Safety

Hazard Codes 

T

Risk Statements 

45-22

Safety Statements 

53-45

RIDADR 

2811

WGK Germany 

3

RTECS 

DD1050000

TSCA 

Yes

HazardClass 

6.1(a)

PackingGroup 

II

HS Code 

29222990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H350May cause cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

3,3'-Dimethoxybenzidine dihydrochloride Chemical Properties,Usage,Production

Description

o-Dianisidine (dihydrochloride) is a colorimetric peroxidase substrate that has been used as a substrate to semi-quantitatively measure lactate, uric acid , and glucose. It has also been used as a reagent for the detection of various metals, thiocyanates, and nitrites. This aromatic amine is initially colorless but turns to violet upon oxidization and is spectrophotometrically measured at a wavelength of 405 nm.

Chemical Properties

Off-white or grey tablets

Uses

o-Dianisidine (3,3′-dimethoxybenzidine) has been used as a component of GO (glucose oxidase) reagent, which is used for measuring the glucose content. It has also been used as a substrate to measure myeloperoxidase activity.

Uses

It is suitable for use in ELISA procedures. In neurohistochemistry o-Dianisidine dihydrochloride has demonstrated perikaryal labeling as well as retrograde and anterograde transport to the primary olfactory cortex. It has also been used for a paper based-micro fluidic device to semi-quantitatively measure lactate, uric acid, and glucose. 3,3'-Dimethoxybenzidine is used principally as an intermediate in the production of commercial bisazobiphenyl dyes for coloring textiles, paper, plastic, rubber, and leather.

General Description

Off-white powder.

Air & Water Reactions

Water soluble.

Reactivity Profile

3,3'-Dimethoxybenzidine dihydrochloride is an ether substituted acidic organic salt. Reacts weakly as a acid to neutralize bases. May react with strong oxidizing agents or strong reducing agents.

Fire Hazard

Flash point data are not available for 3,3'-Dimethoxybenzidine dihydrochloride, but 3,3'-Dimethoxybenzidine dihydrochloride is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Experimental reproductive data. Mutation data reported.When heated to decomposition it emits very toxic fumes of NO, and HCl.