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Dimethylamine hydrochloride

Product Name
Dimethylamine hydrochloride
CAS No.
506-59-2
Chemical Name
Dimethylamine hydrochloride
Synonyms
DMACl;JACS-506-59-2;DIMETHYLAMINE HCL;Dimethylamine hydroc;Imatinib EP Impurity I;Dimethylammoniumchlorid;Metformin impurity F CRS;Dimethylamine HCL Powder;DIMETHYLAMMONIUM CHLORIDE;METHANAMINE HYDROCHLORIDE
CBNumber
CB6140366
Molecular Formula
C2H8ClN
Formula Weight
81.54
MOL File
506-59-2.mol
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Dimethylamine hydrochloride Property

Melting point:
170-173 °C(lit.)
Boiling point:
95.79°C (rough estimate)
Density 
0.8949 (rough estimate)
vapor pressure 
<0.1 hPa (25 °C)
refractive index 
1.4202 (estimate)
storage temp. 
Store below +30°C.
solubility 
H2O: soluble0.5g/10 mL
form 
Crystalline Powder or Crystals
color 
White to off-white
PH
5 (100g/l, H2O, 20℃)
Water Solubility 
3000 g/L (20 ºC)
Sensitive 
Hygroscopic
Merck 
14,3228
BRN 
3589311
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
IQDGSYLLQPDQDV-UHFFFAOYSA-N
CAS DataBase Reference
506-59-2(CAS DataBase Reference)
EPA Substance Registry System
Methanamine, N-methyl-, hydrochloride (506-59-2)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37-37/39-36
WGK Germany 
1
RTECS 
IQ0220000
3-9
TSCA 
Yes
HS Code 
29211190
Toxicity
LD50 in mice (g/kg): 1.21 i.v., 2.00 s.c. (Hazard); LC50 in mice (ppm): 7650 (48 hr), 4725 (14 day); in rats (ppm): 4540 (6 hr) (Steinhagen)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
126365
Product name
Dimethylamine hydrochloride
Purity
99%
Packaging
5g
Price
$18.3
Updated
2021/12/16
Sigma-Aldrich
Product number
8.03052
Product name
Dimethylammonium chloride
Purity
for synthesis
Packaging
5 g
Price
$18.41
Updated
2021/12/16
Sigma-Aldrich
Product number
8.03052
Product name
Dimethylammonium chloride
Purity
for synthesis
Packaging
250 g
Price
$31.63
Updated
2021/12/16
Sigma-Aldrich
Product number
8.03052
Product name
Dimethylammonium chloride
Purity
for synthesis
Packaging
1 kg
Price
$72.98
Updated
2021/12/16
Sigma-Aldrich
Product number
126365
Product name
Dimethylamine hydrochloride
Purity
99%
Packaging
1kg
Price
$76.1
Updated
2021/12/16
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Dimethylamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white crystals

Uses

Dimethylamine hydrochloride is a precursor to several industrially significant compounds.

Uses

As accelerator in vulcanizing rubber, tanning, manufacture of detergent soaps, or attracting boll weevils to exterminate them. As reagent for Mg.

Uses

Dimethylamine hydrochloride is used as an intermediate in the manufacture of pharmaceuticals like ranitidine and metformin, tramadol and amlodipine. It is used as a precursor of atrazine. It is associated with sodium acetate and used to carry out the Willgerodt- Kindler reaction to prepare amides. Its free base reacts with carbon disulfide to get dimethyldithiocarbamate which is used in rubber vulcanization. It is involved in the synthesis of dimethyl-(1-methyl-pyrrol-2-ylmethyl)-amine by reacting with 1-methyl pyrrole and formaldehyde.

Application

Dimethylamine hydrochloride is a raw material for organic synthesis. It is also used as a catalyst and magnesium reagent for acetylation analysis.
Dimethylamine hydrochloride has been used in the preparation of hexamethylmelamine-methyl-14C. It has also been used to prepare the standard solution of methylamine (MA), dimethylamine (DMA), trimethylamine (TMA), and trimethylamine-N-oxide (TMAO) while determing methylamines and trimethylamine-N-oxide in particulate matter. Dimethylamine hydrochloride is used as an intermediate in the manufacture of pharmaceuticals like ranitidine and metformin, amlodipine. It is used as a precursor of atrazine. It is associated with sodium acetate and used to carry out the Willgerodt- Kindler reaction to prepare amides. Its free base reacts with carbon disulfide to get dimethyldithiocarbamate which is used in rubber vulcanization. It is involved in the synthesis of dimethyl-(1-methyl-pyrrol-2-ylmethyl)-amine by reacting with 1-methyl pyrrole and formaldehyde.

Purification Methods

Crystallise the salt from hot CHCl3 or absolute EtOH. It also recrystallises from MeOH/ether solution. Dry it in a vacuum desiccator over H2SO4, then P2O5. Hygroscopic. [Beilstein 4 IV 132.]

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Dimethylamine hydrochloride Suppliers

Shenyang Sinoda Biological Technology Co., LTD
Tel
024-31174117 18002429090
Fax
024-31174117
Email
2193387905@qq.com
Country
China
ProdList
102
Advantage
58
Wuhan Greatwall chemical Co,.LTD
Tel
400-027-6116 18086000087
Fax
QQ: 2680733325
Email
sales@chemgreatwall.com
Country
China
ProdList
1563
Advantage
55
Wuhan hongde yuexin pharmaceutical technology co. LTD
Tel
027-83855391 13657260109
Fax
027-83855391
Email
hbzlkschem2009@163.com
Country
China
ProdList
2856
Advantage
58
Hebei Guanlang Biotechnology Co., Ltd.
Tel
19930505208
Email
515253120@qq.com
Country
China
ProdList
310
Advantage
58
Shijiazhuang Suking Biotechnology Co .,Ltd.
Tel
173-1858-6295 17318586295
Fax
17318586295
Email
sales1@sxbiology.com
Country
China
ProdList
181
Advantage
58
Sichuan Hainuowei Technology Co. Ltd.
Tel
13708085536
Fax
QQ : 121102042
Email
hanovichem@163.com
Country
China
ProdList
3359
Advantage
56
yuyao tuqiang chemical Co.Ltd
Tel
13586691556
Email
281705708@qq.com
Country
China
ProdList
8
Advantage
58
Shanghai Changrun Mai New Material Technology Co., LTD
Tel
13003100670
Email
admin@shanghaicrm.com
Country
China
ProdList
87
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169121
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40310
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30159
Advantage
84
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View Lastest Price from Dimethylamine hydrochloride manufacturers

Wuhan Aoliqisi New Material Technology Co., Ltd.
Product
Dimethylamine hydrochloride 506-59-2
Price
US $30.00/g
Min. Order
1000g
Purity
99%
Supply Ability
20ton/month
Release date
2021-07-09
Wuhan Aoliqisi New Material Technology Co., Ltd.
Product
Dodecylpyridine hydrochloride 506-59-2
Price
US $10.00/g
Min. Order
10g
Purity
99%
Supply Ability
10000kgs/month
Release date
2021-07-08
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Dimethylamine hydrochloride 506-59-2
Price
US $0.99/KG
Min. Order
1KG
Purity
99%
Supply Ability
1KG
Release date
2022-04-01

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