ChemicalBook > CAS DataBase List > Dimethylamine hydrochloride

Dimethylamine hydrochloride

Product Name
Dimethylamine hydrochloride
CAS No.
506-59-2
Chemical Name
Dimethylamine hydrochloride
Synonyms
METHANAMINE HYDROCHLORIDE;DMACl;DIMETHYLAMINE HCL;DIMETHYLAMMONIUM CHLORIDE;DiMethylaMine hydrochlorid;Metformin EP Impurity F HCl;JACS-506-59-2;Dimethylamine hydroc;Imatinib EP Impurity I;Dacarbazine Impurity 3
CBNumber
CB6140366
Molecular Formula
C2H8ClN
Formula Weight
81.54
MOL File
506-59-2.mol
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Dimethylamine hydrochloride Property

Melting point:
170-173 °C(lit.)
Boiling point:
95.79°C (rough estimate)
Density 
0.8949 (rough estimate)
vapor pressure 
<0.1 hPa (25 °C)
refractive index 
1.4202 (estimate)
storage temp. 
Store below +30°C.
solubility 
H2O: soluble0.5g/10 mL
form 
Crystalline Powder or Crystals
color 
White to off-white
PH
5 (100g/l, H2O, 20℃)
Water Solubility 
3000 g/L (20 ºC)
Sensitive 
Hygroscopic
Merck 
14,3228
BRN 
3589311
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
IQDGSYLLQPDQDV-UHFFFAOYSA-N
LogP
-3.28
CAS DataBase Reference
506-59-2(CAS DataBase Reference)
EPA Substance Registry System
Methanamine, N-methyl-, hydrochloride (506-59-2)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37-37/39-36
WGK Germany 
1
RTECS 
IQ0220000
F 
3-9
TSCA 
Yes
HS Code 
29211190
Toxicity
LD50 in mice (g/kg): 1.21 i.v., 2.00 s.c. (Hazard); LC50 in mice (ppm): 7650 (48 hr), 4725 (14 day); in rats (ppm): 4540 (6 hr) (Steinhagen)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.03052
Product name
Dimethylammonium chloride
Purity
for synthesis
Packaging
5G
Price
$25
Updated
2024/03/01
Sigma-Aldrich
Product number
8.03052
Product name
Dimethylammonium chloride
Purity
for synthesis
Packaging
250g
Price
$42.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.03052
Product name
Dimethylammonium chloride
Purity
for synthesis
Packaging
1kg
Price
$98.9
Updated
2024/03/01
Sigma-Aldrich
Product number
8.03052
Product name
Dimethylammonium chloride
Purity
for synthesis
Packaging
25kg
Price
$1650
Updated
2024/03/01
Sigma-Aldrich
Product number
126365
Product name
Dimethylamine hydrochloride
Purity
99%
Packaging
5g
Price
$23
Updated
2024/03/01
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Dimethylamine hydrochloride Chemical Properties,Usage,Production

Description

Dimethylamine hydrochloride is the raw material of organic synthesis, the catalyzer of analysis as an acetylize, and the preparation of azoviolet and dimethylamine aqueous solution. Dimethylamine hydrochloride deoxidation is very capable, and corrodibility is vital, so be usually used in cleaning-type soldering flux. Preparation technology is for slowly splashing into hydrochloric acid in dimethylamine for tradition, and the speed that splashes into is no more than 15 ℃ with temperature, and pH=7-8 is limited. After the reaction finishes, activated carbon decolorizing is added, the filtrate is adjusted to pH=3-4 with hydrochloric acid, decompression is steamed water to the greatest extent, obtaining dimethylamine hydrochloride.

Chemical Properties

White, foliage-like crystals with a melting point of 171°C. Highly soluble in water, soluble in alcohol and chloroform, and insoluble in ether. Exhibits deliquescence.

Uses

Dimethylamine hydrochloride is used as an intermediate in the manufacture of pharmaceuticals like ranitidine and metformin, tramadol and amlodipine. It is used as a precursor of atrazine. It is associated with sodium acetate and used to carry out the Willgerodt- Kindler reaction to prepare amides. Its free base reacts with carbon disulfide to get dimethyldithiocarbamate which is used in rubber vulcanization. It is involved in the synthesis of dimethyl-(1-methyl-pyrrol-2-ylmethyl)-amine by reacting with 1-methyl pyrrole and formaldehyde.

Uses

Dimethylamine hydrochloride is a precursor to several industrially significant compounds.

Uses

As accelerator in vulcanizing rubber, tanning, manufacture of detergent soaps, or attracting boll weevils to exterminate them. As reagent for Mg.

Preparation

Dimethylamine hydrochloride is obtained from the salt formation of dimethylamine and hydrochloric acid.

Application

Dimethylamine hydrochloride serves as a foundational material for organic synthesis and is utilized as a catalyst and magnesium reagent in acetylation analysis. It has been used in producing hexamethylmelamine-methyl-14C and in preparing standard solutions of methylamine (MA), dimethylamine (DMA), trimethylamine (TMA), and trimethylamine-N-oxide (TMAO) to assess the presence of methylamines and trimethylamine-N-oxide in particulate matter.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise the salt from hot CHCl3 or absolute EtOH. It also recrystallises from MeOH/ether solution. Dry it in a vacuum desiccator over H2SO4, then P2O5. Hygroscopic. [Beilstein 4 IV 132.]

Dimethylamine hydrochloride Preparation Products And Raw materials

Raw materials

Dimethylamine

Preparation Products

N,N-Dimethylpiperidin-4-amine 2-METHYL-4-TRIFLUOROMETHYL-NICOTINIC ACID 2-Chloro-N,N-dimethylacetamide 5-BUTYLPYRIDINE-2-CARBONITRILE DIMETHYLAMINOACETYL CHLORIDE HYDROCHLORIDE (3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE FUSARIC ACID Dimethylsulfamoyl chloride Ondansetron 3-AMINO-N,N-DIMETHYL-BENZENESULFONAMIDE (3R)-(+)-3-(DIMETHYLAMINO)PYRROLIDINE Ethacrynic acid N-NITROSODIMETHYLAMINE
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View Lastest Price from Dimethylamine hydrochloride manufacturers

Dorne Chemical Technology co. LTD
Product
Dimethylamine hydrochloride 506-59-2
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
10 ton
Release date
2024-03-26
Hebei Kangcang new material Technology Co., LTD
Product
Dimethylamine hydrochloride 506-59-2
Price
US $20.00-10.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
20
Release date
2024-04-25
Hunan aslsen technology co.,ltd
Product
Dimethylamine Hydrochloride 506-59-2
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-04-15

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