Cinobufotalin

Product Name: Cinobufotalin
CAS No.: 1108-68-5
Chemical Name: Cinobufotalin
Synonyms: Nsc90326;Cinobufotlin;CINOBUFOTALIN;Chinbufotalin;CINOBUFOTALIN(RG);Cinobufotalin std.;Cinobufotalin Standard;Cinobufotalin USP/EP/BP;cinobufotalin venom toad;5beta-Hydroxycinobufagin
CBNumber: CB1410581
Molecular Formula: C26H34O7
Formula Weight: 458.54
MOL File: 1108-68-5.mol

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Cinobufotalin Property

Melting point:: 259-262°
alpha: D20 +11°
Boiling point:: 627.3±55.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
pka: 14.67±0.70(Predicted)
form: White to off-white solid.
color: White to off-white
CAS DataBase Reference: 1108-68-5

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Safety

Hazard Codes: T+
Risk Statements: 26/27/28
Safety Statements: 22-36/37/39-45
RIDADR: UN 2811 6.1/PG 1
WGK Germany: 3
RTECS: EI2991000
HazardClass: 6.1(a)
PackingGroup: II
Toxicity: cat,LD50,intravenous,200ug/kg (0.2mg/kg),"Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 189, 1963.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C1147
Product name: Cinobufotalin
Packaging: 10mg
Price: $416
Updated: 2024/03/01

Cayman Chemical

Product number: 19845
Product name: Cinobufotalin
Packaging: 5mg
Price: $112
Updated: 2024/03/01

Cayman Chemical

Product number: 19845
Product name: Cinobufotalin
Packaging: 25mg
Price: $341
Updated: 2024/03/01

Cayman Chemical

Product number: 19845
Product name: Cinobufotalin
Packaging: 1mg
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 19845
Product name: Cinobufotalin
Packaging: 10mg
Price: $172
Updated: 2024/03/01

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Cinobufotalin Chemical Properties,Usage,Production

Description

Cinobufacin is an indole-type total alkaloid extracted from the dried toad skin of Chinese toad, which has the functions of clearing away heat and detoxifying, reducing swelling and pain, promoting blood circulation and removing blood stasis, softening and dispelling knots.

Application

Cinobufacin can be used for a variety of middle and advanced tumors (lung cancer, breast cancer, cervical cancer, digestive system tumors such as primary liver cancer, gastric cancer, colon cancer, etc.), chronic hepatitis B, especially for chronic hepatitis B virus carriers. Especially prominent.

Side effects

For individual patients, if the dosage is too large or the interval between two administrations is less than 6 to 8 hours, chills and fever may occur about 30 minutes after administration; a small number of patients have local irritation or phlebitis after long-term intravenous infusion, which will slow down the infusion rate. Very few patients may also appear urticaria, dermatitis and so on.

Cinobufotalin Preparation Products And Raw materials

Raw materials

Preparation Products

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Cinobufotalin Suppliers

China 124 France 1 Japan 1 Switzerland 2 The Netherlands 1 United Kingdom 3 United States 21 Global 153

Nanjing Endesa Bio-tech Co., Ltd.

Tel: 025-58862853 18915922038
Fax: +86-025-58862853
Email: sales@endesachem.com
Country: China
ProdList: 591
Advantage: 58

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3921
Advantage: 50

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9978
Advantage: 55

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View Lastest Price from Cinobufotalin manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Cinobufotalin 1108-68-5
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-20

Dideu Industries Group Limited

Product: Cinobufotalin 1108-68-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-02

Shaanxi Dideu Medichem Co. Ltd

Product: Cinobufotalin 1108-68-5
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 800 ton
Release date: 2020-04-30

1108-68-5, CinobufotalinRelated Search:

Ethyl acetate Sodium acetate Vinyl acetate Methyl acetate Glatiramer acetate Butyl acetate Potassium Acetate Tocopheryl acetate ACETATE bufoin injection ALPHA-PYRONE 1,2-EPOXYTETRADECANE (R)-(+)-1,2-Epoxybutane 1,2-Epoxydodecane TERPIN MONOHYDRATE 2,3-EPOXY-2-METHYLBUTANE CIS-1,2-CYCLOPENTANEDIOL (R)-(+)-Glycidol

cinobufotalin venom toad

Cinobufotalin std.

5BETA,20[22]-BUFADIENOLIDE-14,15BETA-EPOXY-3BETA,5ALPHA,16BETA-TRIOL 16-ACETATE

14,15-beta-epoxy-3-beta,5,16-beta-trihydroxy-22-dienolid16-5-beta-bufa-2

CINOBUFOTALIN(RG)

14,15b-Epoxy-3b,5a,16b-trihydroxy-5b,20(22)-bufadienolide 16-acetate

5β,20(22)-Bufadienolide-14,15β-epoxy-3β,5α,16β-triol 16-acetate, 14,15β-Epoxy-3β,5α,16β-trihydroxy-5β,20(22)-bufadienolide 16-acetate

14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv.

5-b-Bufa-20,22-dienolide, 14,15-b-epoxy-3-b,5,16-b-trihydroxy, 16-acetate

Bufa-20,22-dienolide, 16- (acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3.beta.,5.beta.,15.beta.,16.beta.)-

16β-(Acetyloxy)-14,15β-epoxy-3β,5-dihydroxy-5β,14β-bufa-20,22-dienolide

16β-Acetoxy-14,15β-epoxy-3β,5-dihydroxy-5β-bufa-20,22-dienolide

3β,5β-Dihydroxy-16β-acetoxy-14,15β-epoxy-5β-bufa-20,22-dienolide

5.beta.-Bufa-20,22-dienolide, 14,15.beta.-epoxy-3.beta.,5,16.beta.-trihydroxy-, 16-acetate

Cinobufotlin

Nsc90326

14,15β-Epoxy-3β,5α,16β-trihydroxy-5β,20(22)-bufadienolide 16-acetate

5β,20(22)-Bufadienolide-14,15β-epoxy-3β,5α,16β-triol 16-acetate

CINOBUFOTALIN

20,22,5BETA-BUFADIENOLID-14BETA,15BETA-EPOXY-3BETA, 5BETA, 6BETA-TRIOL-16-ACETATE

Cinobufotalin, 98%, from animal extracts

14,15BETA-EPOXY-3BETA,5ALPHA,16BETA-TRIHYDROXY-5BETA,20[22]-BUFADIENOLIDE 16-ACETATE

5beta-Hydroxycinobufagin, HPLC≥98%

Cinobufotalin Standard

Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β,16β)-

Cinobufotalin USP/EP/BP

5beta-Hydroxycinobufagin

Chinbufotalin

(1R,2R,2aR,3aS,3bR,5aS,7S,9aR,9bS,11aR)-5a,7-Dihydroxy-9a,11a-dimethyl-1-(2-oxo-2H-pyran-5-yl)hexadecahydronaphtho[1',2':6,7]indeno[1,7a-b]oxiren-2-yl acetate

1108-68-5

C26H34O7