ChemicalBook > CAS DataBase List > 2,2'-Dithiosalicylic acid

2,2'-Dithiosalicylic acid

Product Name
2,2'-Dithiosalicylic acid
CAS No.
119-80-2
Chemical Name
2,2'-Dithiosalicylic acid
Synonyms
DSTA;DITHIOSALICYLIC ACID;2,2'-disulfanediyldibenzoic acid;NSC 213;NSC 5346;NSC 405662;NSC 633230;AKOS AUF01570;Dithioslicylicacid;2,2'-Dithiodibenzoic
CBNumber
CB1420317
Molecular Formula
C14H10O4S2
Formula Weight
306.36
MOL File
119-80-2.mol
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2,2'-Dithiosalicylic acid Property

Melting point:
287-290 °C(lit.)
Boiling point:
416.97°C (rough estimate)
Density 
1.4555 (rough estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.4950 (estimate)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
3.02±0.36(Predicted)
form 
Powder
color 
Brown
Water Solubility 
insoluble
BRN 
2221810
InChIKey
LBEMXJWGHIEXRA-UHFFFAOYSA-N
LogP
1.61 at 25℃ and pH6.2-6.48
CAS DataBase Reference
119-80-2(CAS DataBase Reference)
EPA Substance Registry System
Benzoic acid, 2,2'-dithiobis- (119-80-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
RTECS 
DG9660000
Hazard Note 
Harmful/irritant
TSCA 
Yes
HS Code 
29309070
Toxicity
LD50 ipr-mus: 367 mg/kg ARZNAD 21,284,71
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2590
Product name
Thimerosal Related Compound A
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
100MG
Price
$534
Updated
2024/03/01
Sigma-Aldrich
Product number
43761
Product name
2,2′-Dithiodibenzoic acid
Purity
≥95.0% (NT)
Packaging
100g
Price
$53.1
Updated
2024/03/01
Sigma-Aldrich
Product number
1659001
Product name
Thimerosal Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1450
Updated
2024/03/01
TCI Chemical
Product number
D1437
Product name
2,2'-Dithiodibenzoic Acid
Purity
>96.0%(HPLC)(T)
Packaging
25g
Price
$83
Updated
2024/03/01
TCI Chemical
Product number
D1437
Product name
2,2'-Dithiodibenzoic Acid
Purity
>96.0%(HPLC)(T)
Packaging
100g
Price
$174
Updated
2024/03/01
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2,2'-Dithiosalicylic acid Chemical Properties,Usage,Production

Chemical Properties

brown powder

Uses

2,2'-Dithiosalicylic acid is an organosulfur compound produced from dibenzothiophene metabolites that is in turn biodegraded into transient metabolites such as benzoic acid.It is used in the preparation of a new class of anti-HIV-1 agents.

Uses

2,2′-Dithiodibenzoic acid may be used for the preparation of novel anionic heptadecanuclear silver(I) cluster, by the reaction with equivalent molar silver oxide under ultrasonic conditions at 50°C. It may be used for the preparation of polyamides containing a disulfide bond in their main chain.

General Description

2,2′-Dithiodibenzoic acid is an sulfhydryl modifying reagent. 2,2′-Dithiodibenzoic acid on cocrystallization with imidazole or 4-methylimidazole affords bis(imidazolium) 2,2′-dithiodibenzoate and 4-methylimidazolium 2-[(2-carboxyphenyl)disulfanyl]benzoate organic salt, respectively. It also cocrystallizes with isonicotinohydrazide from methanol solution to afford the 1:2 cocrystal, 2,2′-dithiodibenzoic acid-isonicotinohydrazide.

Safety Profile

Poison by intraperitoneal route.When heated to decomposition it emits toxic vapors ofSOx.

Synthesis

A preparation method of 2,2'-dithiosalicylic acid is as follows: using anthranilic acid as raw material and performing a diazotization reaction with sodium nitrite and hydrochloric acid at 0 to 10°C to obtain a diazo liquid. The liquid reacts with liquid sulfur dioxide for 0.5 to 3 hours in the presence of a catalyst and a cocatalyst at -20~~-10°C and then is kept at 80~100°C for 0.5~2 hours, cooled, and filtered to obtain 2,2'-Dithiosalicylic acid.

2,2'-Dithiosalicylic acid Preparation Products And Raw materials

Raw materials

Anthranilic acid

Preparation Products

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2,2'-Dithiosalicylic acid Suppliers

Americas 1 Belgium 2 Canada 2 China 379 Czech Republic 1 Europe 4 France 2 Germany 9 India 27 Japan 5 Slovakia 1 South Korea 2 Switzerland 4 The Netherlands 2 Ukraine 2 United Kingdom 18 United States 51 Global 512
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View Lastest Price from 2,2'-Dithiosalicylic acid manufacturers

Jinan Finer Chemical Co., Ltd
Product
2,2'-Dithiosalicylic acid (DSTA) 119-80-2
Price
US $5.00/KG
Min. Order
1KG
Purity
≥99%
Supply Ability
5000mt/year
Release date
2023-07-17
Hebei Zhuanglai Chemical Trading Co Ltd
Product
2,2'-Dithiosalicylic acid 119-80-2
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-12-03
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2,2'-Dithiosalicylic acid 119-80-2
Price
US $0.00/KG
Min. Order
1KG
Purity
96.0%
Supply Ability
1000kg/month
Release date
2021-07-27

119-80-2, 2,2'-Dithiosalicylic acidRelated Search:

Dilauryl thiodipropionate Diphenylthiocarbazide TEREPHTHALIC DIHYDRAZIDE Terephthalic acid Folic acid Thiobenzoic acid Ethyl 2-(Chlorosulfonyl)acetate Citric acid Ascoric Acid Zinc Dialkyl Dithio Phosphate(ZDDP) DIPHENYL DISULFIDE Thiosalicylic acid Salicylic acid 2,2'-Dithiobis(3-methylbenzoic acid) dimethyl 2,2'-dithiobisbenzoate 2,2'-DITHIOBIS(6-FLUOROBENZOIC ACID) 2,2'-Dithiosalicylic acid 2,2'-DITHIOSALICYLIC ACID, DISODIUM SALT,2,2'-DITHIOSALICYLIC ACID, DISODIUM SALT

  • 2,2'-Dithiodibenzoic acid >=95.0% (NT)
  • 2,2’-dithiobis(benzoicacid)
  • 2,2’-dithiobis-benzoicaci
  • Thimerosal Related Compound A
  • DSTA
  • 2,2'-DITHIOSALICYLIC ACID, TECH., 85%
  • 2-Hydroxybenzenecarbothioic acid
  • 2-Carboxyphenyl disulfide, Bis(2-carboxyphenyl) disulfide, Dithiosalicylic acid
  • 2,2'-DITHIOBENZOCI ACID
  • 2,2 -DITHIOSALICYCLIC ACID
  • 2,2 '-dithio-dibenzoate
  • 2-Hydroxybenzenethionothiolic acid
  • o-Hydroxydithiobenzoic acid
  • 2'-Dithiodibenzoic acid
  • 2,2'-Dithiodibenzoic
  • Benzoic acid, 2,2-dithiobis-
  • 2,2'-Dithiosalicylic acid 82%
  • Dithioslicylicacid
  • DL-Tryptophan, 5-methoxy-
  • NSC 405662
  • Bis(o-carboxylphenyl)disulfide
  • 2,2'-Dithiosalicylic acid,98%
  • NSC 213
  • NSC 5346
  • NSC 633230
  • o,o'-Dithiodibenzoic acid
  • 2,2'-DITHIODIBENZOIC ACID FOR SYNTHESIS
  • DTSA)2,2′-Dithiodiben
  • 2,2'-Dithiosalicylic acid(DTSA)
  • 2,2'-disulfanediyldibenzoic acid
  • 2,2'-Disulphanediyldibenzoic acid 82%
  • 2-[(2-carboxylatophenyl)disulfanyl]benzoate
  • 2,2’-dithiodibenzoesaeure
  • 2,2’-dithiodi-benzoicaci
  • bis(o-carboxyphenyl)disulfide
  • AKOS AUF01570
  • 2-(2-CARBOXYPHENYL)DISULFANYLBENZOIC ACID
  • 2,2-DITHIODIBENZOIC ACID
  • 2,2'-DITHIOBENZOIC ACID
  • 2,2-DITHIOBENZOIC ACID
  • 2-CARBOXYPHENYL DISULFIDE
  • BIS(2-CARBOXYPHENYL) DISULFIDE
  • DITHIOSALICYLIC ACID
  • DIPHENYL DISULFIDE-2,2'-DICARBOXYLIC ACID
  • di(2-carboxyphenyl) disulphide
  • 2-Carboxyphenyl disulfide 2,2'-Dithiodibenzoic Acid
  • 2,2'-Dithiosalicy acid
  • 2,2-Dithiodibenzoic acid(Technical)
  • 2,2'-Dithiodibenzoic Acid &gt
  • 2,2'-Dithiosalicylic acid (DSTA)
  • Thimerosal Related Compound A (2,2''-Disulfanediyldibenzoic acid) (1659001)
  • 2,2'-Dithiosalicylic acid
  • 2,2'-Dithiodibenzoic acid
  • 2,2'- dithiobenzoic acid
  • Axitinib Impurity N24
  • 119-80-2
  • 119-60-7
  • 118-80-2