4-NITRO-2-(TRIFLUOROMETHYL)BENZONITRILE
- Product Name
- 4-NITRO-2-(TRIFLUOROMETHYL)BENZONITRILE
- CAS No.
- 320-47-8
- Chemical Name
- 4-NITRO-2-(TRIFLUOROMETHYL)BENZONITRILE
- Synonyms
- BUTTPARK 91\04-59;2-Cyano-5-nitrobenzotr;Enzalutamide Impurity 24;4-Nitro-2-(Trifluoromethyl)Ben;2-CYANO-5-NITROBENZOTRIFLUORIDE;2-Cyano-5-nitrobenzotrifluoride98%;2-Cyano-5-nitrobenzotrifluoride 98%;4-Nitro-2-trifluoromethylbenzotrile;-Nitro-2-(trifluoromethyl)benzonitrile;2-(TRIFLUOROMETHYL)-4-NITROBENZONITRILE
- CBNumber
- CB1436534
- Molecular Formula
- C8H3F3N2O2
- Formula Weight
- 216.12
- MOL File
- 320-47-8.mol
4-NITRO-2-(TRIFLUOROMETHYL)BENZONITRILE Property
- Melting point:
- 49-53 °C(lit.)
- Boiling point:
- 297.7±40.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- color
- White to Yellow to Green
- BRN
- 2281014
- InChI
- 1S/C8H3F3N2O2/c9-8(10,11)7-3-6(13(14)15)2-1-5(7)4-12/h1-3H
- InChIKey
- AGKQJEFSEQHGTA-UHFFFAOYSA-N
- SMILES
- [O-][N+](=O)c1ccc(C#N)c(c1)C(F)(F)F
- CAS DataBase Reference
- 320-47-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 579955
- Product name
- 4-Nitro-2-(trifluoromethyl)benzonitrile
- Purity
- 97%
- Packaging
- 5g
- Price
- $78.1
- Updated
- 2023/06/20
- Product number
- N1068
- Product name
- 4-Nitro-2-(trifluoromethyl)benzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $75
- Updated
- 2026/03/19
- Product number
- N1068
- Product name
- 4-Nitro-2-(trifluoromethyl)benzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $249
- Updated
- 2025/07/31
- Product number
- N900908
- Product name
- 4-Nitro-2-(trifluoromethyl)benzonitrile
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- J97683
- Product name
- 4-Nitro-2-(trifluoromethyl)benzonitrile
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
4-NITRO-2-(TRIFLUOROMETHYL)BENZONITRILE Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
4-Nitro-2-(trifluoromethyl)benzonitrile is a benzonitrile derivative containing trifluoromethyl and nitro substituents at the 2 and 4 positions. It can be used as an electrochemical material for lithium ion battery research. In the field of organic synthesis, it is also used in the preparation of substituted phenoxyphenyl ketones, which can be further reacted to obtain substituted 1-[4-phenoxy-2-(haloalkyl)phenyl]-2-(1,2,4-triazol-1-yl)ethanol compounds.
Synthesis
Potassium cyanide was added to an anhydrous acetonitrile solution of 2-chloro-5-iodobenzene 4-nitro-2-(trifluoromethyl)aniline at room temperature, and the mixture was heated at 60C for 25 min. with the addition of an aqueous saturated sodium thiosulfate solution (20 ) mL), the mixture was concentrated under reduced pressure to remove most of the acetonitrile, and the aqueous phase was extracted with ethyl acetate (4 x 10 mL). The combined organics were dried over anhydrous magnesium sulfate. It was filtered and concentrated under reduced pressure to give a solid. The solid was preloaded onto silica. The residue was purified by fast column chromatography, eluting with 40 g of silica and 0-10% heptane solution with ethyl acetate. The fractions with the product were combined and evaporated to obtain the product 4-nitro-2-(trifluoromethyl)benzonitrile.
4-NITRO-2-(TRIFLUOROMETHYL)BENZONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-NITRO-2-(TRIFLUOROMETHYL)BENZONITRILE manufacturers
- Product
- 4-NITRO-2-(TRIFLUOROMETHYL)BENZONITRILE 320-47-8
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- as request
- Release date
- 2018-12-24