4'-BROMO-3-CHLOROPROPIOPHENONE
- Product Name
- 4'-BROMO-3-CHLOROPROPIOPHENONE
- CAS No.
- 31736-73-9
- Chemical Name
- 4'-BROMO-3-CHLOROPROPIOPHENONE
- Synonyms
- Bupropion Impurity 45;3-chloro-4-bromopropiophenone;P-BROMO-3-CHLOROPROPIOPHENONE;4'-Bromo-β-chloropropiophenone;4'-Bromo-3-chloropropiophenone;4'-Bromo-3-chloropropiophenone;4-BROMO-BETA-CHLOROPROPIOPHENONE;4,4-diphenyloxazolidine-2,5-dione;4'-Bromo-3-chloropropiophenone,99%;4'-Bromo-3-chloropropiophenone,97%
- CBNumber
- CB1450255
- Molecular Formula
- C9H8BrClO
- Formula Weight
- 247.52
- MOL File
- 31736-73-9.mol
4'-BROMO-3-CHLOROPROPIOPHENONE Property
- Melting point:
- 54-59 °C(lit.)
- Boiling point:
- 333.8±27.0 °C(Predicted)
- Density
- 1.5182 (rough estimate)
- vapor pressure
- 0.016Pa at 25℃
- refractive index
- 1.5963 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder
- color
- White
- Water Solubility
- 36mg/L at 20℃
- BRN
- 1944367
- LogP
- 3.2 at 22℃
- CAS DataBase Reference
- 31736-73-9(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 545414
- Product name
- 4′-Bromo-3-chloropropiophenone
- Purity
- 95%
- Packaging
- 5g
- Price
- $138
- Updated
- 2023/06/20
- Product number
- B698125
- Product name
- 1-(4-Bromophenyl)-3-chloropropan-1-one
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- J98062
- Product name
- 1-(4-Bromophenyl)-3-chloropropan-1-one
- Packaging
- 25g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- AK-48143
- Product name
- 1-(4-Bromophenyl)-3-chloropropan-1-one
- Purity
- 98%
- Packaging
- 25g
- Price
- $59
- Updated
- 2021/12/16
- Product number
- 002958
- Product name
- 4'-Bromo-3-chloropropiophenone
- Purity
- 98%
- Packaging
- 25g
- Price
- $74
- Updated
- 2021/12/16
4'-BROMO-3-CHLOROPROPIOPHENONE Chemical Properties,Usage,Production
Chemical Properties
light yellow to light brown crystalline powder
General Description
4′-Bromo-3-chloropropiophenone, a halogenated propiophenone derivative, is also known as 1-(4-bromophenyl)-3-chloro-1-propanone. Its molecular geometry has been studied based on density functional theory (DFT) calculations, FTIR and FT Raman spectra.
Flammability and Explosibility
Not classified
Synthesis
108-86-1
161386-38-5
625-36-5
31736-73-9
The general procedure for the synthesis of 4'-bromo-3-chloropropiophenone from bromobenzene, compound (CAS:161386-38-5) and 3-chloropropionyl chloride was as follows: first, a solution was prepared by dissolving 3-chloropropionyl chloride (15 mL) in methylene chloride (10 mL). Subsequently, the solution was slowly added to a stirring suspension of aluminum chloride (20.1 g) in methylene chloride (35 mL) and the mixture was stirred at room temperature for 15 minutes. Next, the dichloromethane (10 mL) mixture of bromobenzene (15 mL) was added in batches over a period of 1 hour. After addition, the reaction mixture continued to be stirred at room temperature for 16 hours. Upon completion of the reaction, the mixture was quenched by pouring it into a mixture of ice and 1N aqueous hydrochloric acid. The organic phase was separated, washed sequentially with water and saturated aqueous sodium bicarbonate, dried (using MgSO?), and the solvent evaporated. Finally, the residue was purified by column chromatography using a 15:1 mixture of petroleum ether and ethyl acetate as eluent to afford the target product 4-bromophenyl 2-chloroethyl ketone (27.9 g, 85% yield).
References
[1] Patent: US5332757, 1994, A
4'-BROMO-3-CHLOROPROPIOPHENONE Preparation Products And Raw materials
Raw materials
Preparation Products
4'-BROMO-3-CHLOROPROPIOPHENONE Suppliers
- Tel
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- sales@kemix.com.au
- Country
- Australia
- ProdList
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- Advantage
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View Lastest Price from 4'-BROMO-3-CHLOROPROPIOPHENONE manufacturers
- Product
- 4'-BROMO-3-CHLOROPROPIOPHENONE 31736-73-9
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-04-29
- Product
- 4'-BROMO-3-CHLOROPROPIOPHENONE 31736-73-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-04
- Product
- 4'-Bromo-3-chloropropiophenone 31736-73-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-19