ChemicalBook > CAS DataBase List > 4'-BROMO-3-CHLOROPROPIOPHENONE

4'-BROMO-3-CHLOROPROPIOPHENONE

Product Name: 4'-BROMO-3-CHLOROPROPIOPHENONE
CAS No.: 31736-73-9
Chemical Name: 4'-BROMO-3-CHLOROPROPIOPHENONE
Synonyms: Bupropion Impurity 45;3-chloro-4-bromopropiophenone;P-BROMO-3-CHLOROPROPIOPHENONE;4'-Bromo-β-chloropropiophenone;4'-Bromo-3-chloropropiophenone;4'-Bromo-3-chloropropiophenone;4-BROMO-BETA-CHLOROPROPIOPHENONE;4,4-diphenyloxazolidine-2,5-dione;4'-Bromo-3-chloropropiophenone,99%;4'-Bromo-3-chloropropiophenone,97%
CBNumber: CB1450255
Molecular Formula: C9H8BrClO
Formula Weight: 247.52
MOL File: 31736-73-9.mol

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4'-BROMO-3-CHLOROPROPIOPHENONE Property

Melting point:: 54-59 °C(lit.)
Boiling point:: 333.8±27.0 °C(Predicted)
Density: 1.5182 (rough estimate)
vapor pressure: 0.016Pa at 25℃
refractive index: 1.5963 (estimate)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
form: powder
color: White
Water Solubility: 36mg/L at 20℃
BRN: 1944367
LogP: 3.2 at 22℃
CAS DataBase Reference: 31736-73-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: UN1759
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2914790090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 545414
Product name: 4′-Bromo-3-chloropropiophenone
Purity: 95%
Packaging: 5g
Price: $138
Updated: 2023/06/20

TRC

Product number: B698125
Product name: 1-(4-Bromophenyl)-3-chloropropan-1-one
Packaging: 1g
Price: $55
Updated: 2021/12/16

AK Scientific

Product number: J98062
Product name: 1-(4-Bromophenyl)-3-chloropropan-1-one
Packaging: 25g
Price: $55
Updated: 2021/12/16

Ark Pharm

Product number: AK-48143
Product name: 1-(4-Bromophenyl)-3-chloropropan-1-one
Purity: 98%
Packaging: 25g
Price: $59
Updated: 2021/12/16

Oakwood

Product number: 002958
Product name: 4'-Bromo-3-chloropropiophenone
Purity: 98%
Packaging: 25g
Price: $74
Updated: 2021/12/16

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4'-BROMO-3-CHLOROPROPIOPHENONE Chemical Properties,Usage,Production

Chemical Properties

light yellow to light brown crystalline powder

General Description

4′-Bromo-3-chloropropiophenone, a halogenated propiophenone derivative, is also known as 1-(4-bromophenyl)-3-chloro-1-propanone. Its molecular geometry has been studied based on density functional theory (DFT) calculations, FTIR and FT Raman spectra.

Flammability and Explosibility

Not classified

Synthesis

108-86-1

161386-38-5

625-36-5

31736-73-9

The general procedure for the synthesis of 4'-bromo-3-chloropropiophenone from bromobenzene, compound (CAS:161386-38-5) and 3-chloropropionyl chloride was as follows: first, a solution was prepared by dissolving 3-chloropropionyl chloride (15 mL) in methylene chloride (10 mL). Subsequently, the solution was slowly added to a stirring suspension of aluminum chloride (20.1 g) in methylene chloride (35 mL) and the mixture was stirred at room temperature for 15 minutes. Next, the dichloromethane (10 mL) mixture of bromobenzene (15 mL) was added in batches over a period of 1 hour. After addition, the reaction mixture continued to be stirred at room temperature for 16 hours. Upon completion of the reaction, the mixture was quenched by pouring it into a mixture of ice and 1N aqueous hydrochloric acid. The organic phase was separated, washed sequentially with water and saturated aqueous sodium bicarbonate, dried (using MgSO?), and the solvent evaporated. Finally, the residue was purified by column chromatography using a 15:1 mixture of petroleum ether and ethyl acetate as eluent to afford the target product 4-bromophenyl 2-chloroethyl ketone (27.9 g, 85% yield).

References

[1] Patent: US5332757, 1994, A

4'-BROMO-3-CHLOROPROPIOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-BROMO-3-CHLOROPROPIOPHENONE Suppliers

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View Lastest Price from 4'-BROMO-3-CHLOROPROPIOPHENONE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 4'-BROMO-3-CHLOROPROPIOPHENONE 31736-73-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-04-29

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4'-BROMO-3-CHLOROPROPIOPHENONE 31736-73-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-04

Henan Aochuang Chemical Co.,Ltd.

Product: 4'-Bromo-3-chloropropiophenone 31736-73-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-19

31736-73-9, 4'-BROMO-3-CHLOROPROPIOPHENONERelated Search:

2-BROMO-3'-CHLOROPROPIOPHENONE Methyl 3,5-dibromo-4-chlorosalicylate Methyl 5-bromo-4-chloro-2-hydroxybenzoate 5-Bromo-4-chlorosalicylic acid 4'-BROMO-3-CHLOROPROPIOPHENONE 5-BROMO-4-CHLORO-2-FLUOROBENZOIC ACID 5-Bromo-4-chloro-2-methoxybenzoic acid 3-Chloropropiophenone 4'-Bromopropiophenone METHYL 2-AMINO-5-BROMO-4-CHLOROBENZOATE BUTTPARK 80\07-66 3-Bromo-2,4-dichlorobenzoic acid Methyl 5-bromo-4-chloro-2-fluorobenzoate Methyl 5-bromo-4-chloro-2-methoxybenzoate ethyl 3-bromo-4-chlorobenzoate methyl 3-bromo-4-chlorobenzoate 2-bromo-4-chloropropiophenone 2-bromo-2'-chloropropiophenone

4'-Bromo-β-chloropropiophenone

4-bromophenyl 2-chloroethyl ketone

1-(4-Bromophenyl)-3-chloropropan-1-one

P-BROMO-3-CHLOROPROPIOPHENONE

4'-Bromo-3-chloropropiophenone,97%

4'-Bromo-3-chloropropiophenone,99%

4-BROMO-BETA-CHLOROPROPIOPHENONE

1-(4-BROMOPHENYL)-3-CHLORO-1-OXOPROPANE

3-chloro-4-bromopropiophenone

4'-Bromo-3-chloropropiophenone 98%

3-chloro-1-(4-bromophenyl)propan-1-one

4'-Bromo-3-chloropropiophenone,98%

1-(4-Bromophenyl)-3-chloro-1-propanone

4,4-diphenyloxazolidine-2,5-dione

1-Propanone, 1-(4-bromophenyl)-3-chloro-

Bupropion Impurity 45

4'-Bromo-3-chloropropiophenone

4′-Bromo-3-chloropropiophenone, CAS 31736-73-9

4'-Bromo-3-chloropropiophenone

31736-73-9

C9H8BrClO

BrC6H4COCH2CH2Cl

Ketones

Organic Building Blocks

Building Blocks

Carbonyl Compounds

Building Blocks

Carbonyl Compounds

Chemical Synthesis

Organic Building Blocks

Carbonyl Compounds

Ketones