Ancymidol Property

Melting point:

110-111°C

Boiling point:

399.55°C (rough estimate)

Density 

1.1055 (rough estimate)

refractive index 

1.6280 (estimate)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

12.62±0.29(Predicted)

color 

White to Off-White

Water Solubility 

0.65g/L(25 ºC)

λmax

272nm(lit.)

CAS DataBase Reference

12771-68-5(CAS DataBase Reference)

NIST Chemistry Reference

Ancymidol(12771-68-5)

EPA Substance Registry System

Ancymidol (12771-68-5)

Safety

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

UV9280000

HS Code 

2933599590

Toxicity

LD50 in rats, mice (mg/kg): 4500, 5000 orally (Snel, Gramlich)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Ancymidol Chemical Properties,Usage,Production

Chemical Properties

Ancymidol is a white to buff colored crystalline or granular solid. Slightly aromatic odor.

Uses

Ancymidol has been used as the cytochrome P450 inhibitor to study its effects on Cyanidioschyzon merolae?strain.

Uses

Plant growth regulator.

Definition

ChEBI: A tertiary alcohol that is methanol in which the hydrogens attached to the carbon are replaced by cyclopropyl, p-methoxyphenyl and pyrimidin-5-yl groups. By inhibiting gibberellin biosynthesis, ancymidol reduces plant growth, resulting in redu ed internode elongation and thus more compact plants. It is used in the commercial production of a wide variety of container-grown bedding and foliage plants, including chrysanthemums, Easter lilies and poinsettias.

General Description

Ancymidol, a-cyclopropyl-a-(4-methoxyphenyl)-5-pyrimidinemethanol (EL-53 1), a plant growth retardant is a synthetic pyrimidine analogue. It is also a weak fungitoxic.

Biochem/physiol Actions

Ancymidol is a pyrimidine-class plant cell endocrine disruptor plant growth regulator that interferes with gibberellin and cellulose biosynthesis.

Potential Exposure

Ancymidol is a plant growth regulator registered for treating container-grown herbaceous plants, ornamental woody shrubs, and bedding plants grown in greenhouses and other plant bedding areas for primarily commercial production. Growth regulator used on plants such as chrysanthemums, certain lilies, and poinsettias effects produced by ancymidol are the result of inhibition of gibberellin biosynthesis. It produces a more compact growth form by suppressing elongation.

Incompatibilities

Dust may form explosive mixture with air. Ancymidol may react vigorously with oxidizing agents. Mixtures with concentrated hydrogen peroxide or strong mineral acids (e.g., nitric, sulfuric, perchloric) may cause explosions. Mixtures with hypochlorous acid, lead perchlorate, chlorine, bleaches, including sodium hypochlorite; mixed water/carbon tetrachloride solution; trichloroisocyanuric acid form methyl hypochlorite, which can be explosive, especially when exposed to sunlight or heat. May react with metallic aluminum at high temperature. Flow or agitation of substance may generate electrostatic charges due to low conductivity; ground all equipment containing this material. May attacks some plastics, rubber, and coatings.

Waste Disposal

Dispose of contents and container to an approved waste disposal plant. All federal, state, and local environmental regulations must be observed. References