KetoconazoleN-Oxide

Product Name: KetoconazoleN-Oxide
CAS No.: 254912-65-7
Chemical Name: KetoconazoleN-Oxide
Synonyms: KetoconazoleN-Oxide;Ketoconazole N-Oxide (and enantiomer);1-(4-(((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-acetylpiperazine 1-oxide;Ethanone, 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-oxido-1-piperazinyl]-, rel-;rel-1-(4-(((2R,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-acetylpiperazine 1-oxide (Ketoconazole Impurity)
CBNumber: CB14631825
Molecular Formula: C26H28Cl2N4O5
Formula Weight: 547.43
MOL File: 254912-65-7.mol

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KetoconazoleN-Oxide Property

pka: 6.88±0.12(Predicted)

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Hazard and Precautionary Statements (GHS)

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KetoconazoleN-Oxide Chemical Properties,Usage,Production

Uses

Ketoconazole N-?Oxide is an impure analogue of Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.

KetoconazoleN-Oxide Preparation Products And Raw materials

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254912-65-7, KetoconazoleN-OxideRelated Search:

rac-trans-Ketoconazole 1,3-Difluorobenzene 2,3-Dehydro Ketoconazole cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate 2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL METHYL)-1,3-DIOXOLANE-4-METHANOL Ketoconazole Impurity 1 2',4'-Dichloroacetophenone Ketoconazole Impurity 9 (Ketoconazole Hydroxymethyl Impurity) Ketoconazole Impurity 6 KETOCONAZOLE INTERMEDIATE Ketoconazole Impurity 4 2,2,2-trideuterio-1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone Ketoconazole Ketoconazole Impurity 15 cis-1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine Tosyl chloride 4-(1-Acetylpiperazin-4-yl)phenol Ketoconazole Impurity 3

KetoconazoleN-Oxide

Ethanone, 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-oxido-1-piperazinyl]-, rel-

Ketoconazole N-Oxide (and enantiomer)

1-(4-(((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-acetylpiperazine 1-oxide

rel-1-(4-(((2R,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-acetylpiperazine 1-oxide (Ketoconazole Impurity)

254912-65-7