Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
- Product Name
- Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
- CAS No.
- 106246-33-7
- Chemical Name
- Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
- Synonyms
- M-CDEA;LONZACURE(R) M-CDEA-GS;4-[(4-amino-2-chloro-3,5-diethylphenyl)methyl]-3-chloro-2,6-diethylaniline;JADEWIN MCDEA;LONZACURE(R) M-CDEA;LABOTEST-BB LT00159326;4,4'-METHYLENEBIS(3-CHLORO-2,6-DIETHYLAN;4,4'-Methandiylbis(3-chlor-2,6-diethylanilin);4,4'-Methandiylbis(3-chlor-2,6-diethylanilin);Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
- CBNumber
- CB1476536
- Molecular Formula
- C21H28Cl2N2
- Formula Weight
- 379.37
- MOL File
- 106246-33-7.mol
Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Property
- Melting point:
- 88 °C
- Boiling point:
- 506.4±45.0 °C(Predicted)
- Density
- 1.154±0.06 g/cm3(Predicted)
- bulk density
- 610-650kg/m3
- vapor pressure
- 0Pa at 25℃
- storage temp.
- Store below +30°C.
- solubility
- 17000 in mg/100g standard fat at 20 ℃
- form
- powder to lump
- pka
- 3.76±0.25(Predicted)
- color
- White to Light yellow to Light orange
- Water Solubility
- 20μg/L at 20℃
- InChI
- InChI=1S/C21H28Cl2N2/c1-5-12-9-14(18(22)16(7-3)20(12)24)11-15-10-13(6-2)21(25)17(8-4)19(15)23/h9-10H,5-8,11,24-25H2,1-4H3
- InChIKey
- VIOMIGLBMQVNLY-UHFFFAOYSA-N
- SMILES
- C(C1=CC(CC)=C(N)C(CC)=C1Cl)C1=CC(CC)=C(N)C(CC)=C1Cl
- LogP
- 6.5 at 20℃
- CAS DataBase Reference
- 106246-33-7(CAS DataBase Reference)
- EPA Substance Registry System
- Benzenamine, 4,4'-methylenebis[3-chloro-2,6-diethyl- (106246-33-7)
Safety
- HS Code
- 2921.59.1700
N-Bromosuccinimide Price
- Product number
- 8.14676
- Product name
- 4,4′-Methylenebis(3-chloro-2,6-diethylaniline)
- Purity
- for synthesis
- Packaging
- 25G
- Price
- $45.5
- Updated
- 2025/07/31
- Product number
- M3183
- Product name
- 4,4'-Methylenebis(3-chloro-2,6-diethylaniline)
- Packaging
- 25G
- Price
- $40
- Updated
- 2025/07/31
- Product number
- FB55177
- Product name
- Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
- Packaging
- 100g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FB55177
- Product name
- Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
- Packaging
- 250g
- Price
- $147.5
- Updated
- 2021/12/16
- Product number
- 098558
- Product name
- 4,4'-Methylenebis(3-chloro-2,6-diethylaniline)
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $189
- Updated
- 2021/12/16
Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Chemical Properties,Usage,Production
Chemical Properties
Crystalline Powder
Uses
LONZACURE(R) M-CDEA is an excellent chain extender for elastomeric polyurethanes (PU) and also a curing agent for epoxides (EP). It provides improved mechanical and dynamic properties which cannot be achieved with standard formulations.
Uses
LONZACURE(R) M-CDEA GS is the granulated version of LONZACURE(R) M-CDEA and therefore especially suitable for automatic feeding systems in production lines. It is an excellent chain extender for elastomeric polyurethanes (PU) and also.
Flammability and Explosibility
Not classified
Synthesis
13680-35-8
106246-33-7
The general procedure for the synthesis of 4,4'-methylenebis(2,6-diethylaniline) from 4,4'-methylenebis(3-chloro-2,6-diethylaniline) is as follows: 310 g (1 mol) of 4,4'-methylenebis(2,6-diethylaniline) (MDEA) was added to a three-necked flask fitted with a stirrer, thermometer and dropping funnel. At room temperature, 292.5 g (2.4 mol) of 30% hydrochloric acid solution was slowly added through the dropping funnel and stirred for 15 minutes until complete dissolution. Subsequently, 255.5 g (2.1 mol) of 30% hydrochloric acid solution was added, the reaction temperature was maintained at 45 °C and 262.3 g (2.7 mol) of 35% hydrogen peroxide solution was added slowly dropwise at this temperature and the dropwise process lasted for 2 hours. After completion of the dropwise addition, the reaction temperature was raised to 65°C and maintained for 1 hour. After completion of the reaction, the reaction mixture was cooled to below 10°C and left to stand for 10 hours. The solids and liquids were separated by pressurized filtration. The acidic mother liquor obtained from the separation was stored in an analytical grade vessel for subsequent synthesis of 4,4'-methylenebis(2,6-diethylaniline) (MDEA). The solid obtained by filtration was transferred to a three-necked flask and 200 g of water was added, followed by 280 g of 31% sodium hydroxide solution and stirred until neutralization was complete. After neutralization, the aqueous phase was separated by cooling, and the resulting solid was recrystallized from methanol using conventional methods to obtain white granular crystals, i.e., the target product 4,4'-methylenebis(3-chloro-2,6-diethylaniline). The purity of the product was analyzed by high performance liquid chromatography (HPLC) as 95.8%, in which 3,5-dichloro-4,4'-methylenebis(2,6-diethylaniline) was 0.5% and 3-chloro-4,4'-methylenebis(2,6-diethylaniline) was 1.3%. The above steps were repeated, the aqueous phase was separated after neutralization, the solid obtained was cooled and the fractions with boiling points of 245-250°C (fractions 7-8) were collected using a 30 x 0.5 magnetic ring distillation column. After distillation, the content of 4,4'-methylenebis(3-chloro-2,6-diethylaniline) was increased to 99.3% with a distillation yield of 95%, and this product can meet the demand of high-end polyurethane products.
References
[1] Patent: CN108329212, 2018, A. Location in patent: Paragraph 0040-0045
[2] Patent: CN105693526, 2016, A. Location in patent: Paragraph 0028; 0030; 0031
Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Preparation Products And Raw materials
Raw materials
Preparation Products
Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Suppliers
- Tel
- 18357035212
- 757514698@qq.com
- Country
- China
- ProdList
- 26
- Advantage
- 58
- Tel
- 022-66880623
- Fax
- 86(0)22-66880086
- sales@tjzxchem.com
- Country
- China
- ProdList
- 613
- Advantage
- 60
- Tel
- 0512-58961066 18921980669
- Fax
- 86-0512-58961068
- sales@yaruichem.com
- Country
- China
- ProdList
- 35
- Advantage
- 64
- Tel
- 400-6206333 13167063860
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 48457
- Advantage
- 58
- Tel
- 0512-58961066 18921980669
- Fax
- 0512-58961068
- sales@yaruichem.com
- Country
- China
- ProdList
- 40
- Advantage
- 62
- Tel
- 4008-755-333 18080918076
- Fax
- 028-86757656
- 800078821@qq.com
- Country
- China
- ProdList
- 9718
- Advantage
- 55
- Tel
- 13971561712, 13995564702, 027-50664929
- Fax
- 027-50664927
- hbeixys2001@163.com
- Country
- China
- ProdList
- 3120
- Advantage
- 55
- Tel
- 0554-2106669
- Fax
- 0554-2666215
- sales1@kedichem.com
- Country
- China
- ProdList
- 4924
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 400-008-9730,021-54359730 400-008-9730
- Fax
- 021-54353864
- info@chemxyz.com
- Country
- China
- ProdList
- 3057
- Advantage
- 60
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 15873
- Advantage
- 55
- Tel
- 025-57018978 18251899859
- Fax
- 025-57018008
- sales@chalf-pharm.com
- Country
- China
- ProdList
- 5674
- Advantage
- 50
- Tel
- Fax
- -
- xg01_gj@163.com
- Country
- China
- ProdList
- 9484
- Advantage
- 50
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 0519-85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
- Tel
- 0532-68077006 13658692156
- Fax
- 0532-68077006
- zandrew@jadenmtc.com
- Country
- China
- ProdList
- 306
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 0751-2886750 13927877953
- Fax
- 0751-2886750
- 3005811397@qq.com
- Country
- China
- ProdList
- 13305
- Advantage
- 58
- Tel
- 027-83778876 13667159345
- Fax
- 027-83778876
- 13667159345@163.com
- Country
- China
- ProdList
- 1997
- Advantage
- 55
- Tel
- +86-21-5877 1921
- Fax
- +86-21-5877 1925
- info@chemofchina.com
- Country
- China
- ProdList
- 9653
- Advantage
- 55
- Tel
- 021-021-52271985 17721149837
- Fax
- +86 (21) 52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 19800
- Advantage
- 60
- Tel
- 025-58859352 18068836627
- Fax
- (5)02557626880
- dt3@aikonchem.com
- Country
- China
- ProdList
- 15493
- Advantage
- 58
- Tel
- 027-87466105 15377573527
- 2678564200@qq.com
- Country
- China
- ProdList
- 17987
- Advantage
- 58
- Tel
- 400-8210725 400821072
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 25000
- Advantage
- 58
- Tel
- 027-51831887 15337167856
- Fax
- 027-51837635 QQ1165326703
- hubeixinyuanshun@163.com
- Country
- China
- ProdList
- 10295
- Advantage
- 58
- Tel
- 027-63496417 13007129042
- Fax
- 13476107660
- 3294393103@qq.com
- Country
- China
- ProdList
- 295
- Advantage
- 58
- Tel
- 0371-037163312495,13303845143 13303845143
- Fax
- QQ3001379618
- 3001379618@qq.com
- Country
- China
- ProdList
- 10267
- Advantage
- 58
- Tel
- 010-62971590 18548936886
- Fax
- 010-62340519
- 3462612863@qq.com
- Country
- China
- ProdList
- 10063
- Advantage
- 58
- Tel
- 0571-88906230
- Fax
- 0571-88902500
- shenlu@shoufuchem.com
- Country
- China
- ProdList
- 497
- Advantage
- 58
- Tel
- 021-67121386, 800-988-0390
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 5391
- Advantage
- 58
- Tel
- 0371-55055611 18137792234
- Fax
- QQ：3002694073
- 3002694073@qq.com
- Country
- China
- ProdList
- 9987
- Advantage
- 58
- Tel
- +86-13131129325
- Fax
- 86-0311-66562153
- sales1@chuanghaibio.com
- Country
- China
- ProdList
- 5249
- Advantage
- 58
- Tel
- +8615255079626
- eric@witopchemical.com
- Country
- China
- ProdList
- 23541
- Advantage
- 58
- Tel
- +8618531123677
- faithe@yan-xi.com
- Country
- China
- ProdList
- 5853
- Advantage
- 58
- Tel
- 021-64478606 +8615900664856
- daeyeon001@vip.163.com
- Country
- China
- ProdList
- 2062
- Advantage
- 58
- Tel
- +86-0551-65418684 +8618949823763
- Fax
- 0086-551-65418684
- sales@tnjchem.com
- Country
- China
- ProdList
- 25356
- Advantage
- 58
- Tel
- +8615986615575
- Fax
- 0086-13651442114
- info@codchem.com
- Country
- China
- ProdList
- 20342
- Advantage
- 58
- Tel
- +86-0571-88938639 +8617705817739
- Fax
- +86-571-88938652，+86-571- 88492614
- info@dycnchem.com
- Country
- China
- ProdList
- 52846
- Advantage
- 58
- Tel
- 86-571-88216897,88216896 13588875226
- Fax
- 86-571-88216895
- sales@hzclap.com
- Country
- CHINA
- ProdList
- 6312
- Advantage
- 58
- Tel
- 0086 18039857276 18039857276
- Country
- CHINA
- ProdList
- 2783
- Advantage
- 58
- Tel
- +86-5922680277 +86-13806087780
- sale@simagchem.com
- Country
- China
- ProdList
- 17346
- Advantage
- 58
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- chemwill_asia@126.com
- Country
- CHINA
- ProdList
- 23912
- Advantage
- 58
- Tel
- +8615350571055
- Fax
- whatapp+8619930503282
- Sibel@chuanghaibio.com
- Country
- China
- ProdList
- 8768
- Advantage
- 58
- Tel
- 0711-3812399 18062309155
- 156941107@qq.com
- Country
- China
- ProdList
- 2999
- Advantage
- 58
- Tel
- +86-86-5926051114 +8615060885618
- sales@amoychem.com
- Country
- China
- ProdList
- 6369
- Advantage
- 58
- Tel
- 027-83389957 18627766980
- Fax
- 027-83389957
- 914018854@qq.com
- Country
- China
- ProdList
- 282
- Advantage
- 58
- Tel
- +86-023-6139-8061 +86-86-13650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39927
- Advantage
- 58
- Tel
- 18327024450
- Fax
- 183-27024450
- 2130026275@qq.com
- Country
- China
- ProdList
- 4553
- Advantage
- 58
View Lastest Price from Bis(4-amino-2-chloro-3,5-diethylphenyl)methane manufacturers
- Product
- Bis(4-amino-2-chloro-3 5-diethylphenyl)methane Maeda 106246-33-7
- Price
- US $79.00-38.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-12-17
- Product
- Bis(4-amino-2-chloro-3,5-diethylphenyl)methane 106246-33-7
- Price
- US $10.00-8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2025-03-14
- Product
- 4,4'-methylenebis(3-chloro-2,6-diethyl-aniline) 106246-33-7
- Price
- US $0.00/KG
- Min. Order
- 25KG
- Purity
- 98.5%
- Supply Ability
- 100MT/Month
- Release date
- 2024-04-15