3-Fluoro-4-methylphenol

Product Name: 3-Fluoro-4-methylphenol
CAS No.: 452-78-8
Chemical Name: 3-Fluoro-4-methylphenol
Synonyms: 3-FLUORO-P-CRESOL;3-Fluoro-p-cresol>3-FLUORO-4-METHYLPHENOL;3-Fluoro-p-cresol (OH=1);2-Fluoro-4-hydroxytoluene;Phenol, 3-fluoro-4-methyl-;3-Fluoro-4-methylphenol, JRD,
CBNumber: CB1478242
Molecular Formula: C7H7FO
Formula Weight: 126.13
MOL File: 452-78-8.mol

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3-Fluoro-4-methylphenol Property

Melting point:: 72 °C
Boiling point:: 196 °C
Density: 1.17
refractive index: 1.5150
Flash point:: 29 °C
storage temp.: Inert atmosphere,Room Temperature
form: powder to lump
pka: 9.27±0.18(Predicted)
color: White to Light yellow to Light orange
Odor: Phenol-like
InChI: InChI=1S/C7H7FO/c1-5-2-3-6(9)4-7(5)8/h2-4,9H,1H3
InChIKey: GJOOCAXPERKNMN-UHFFFAOYSA-N
SMILES: C1(O)=CC=C(C)C(F)=C1
CAS DataBase Reference: 452-78-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 21/22-34-52-36-22
Safety Statements: 26-36/37/39-60-45
RIDADR: 2922
Hazard Note: Irritant
HazardClass: 8
HS Code: 29081990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H302Harmful if swallowed

H312Harmful in contact with skin

H314Causes severe skin burns and eye damage

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: F0481
Product name: 3-Fluoro-p-cresol
Purity: >98.0%(GC)
Packaging: 1g
Price: $32
Updated: 2024/03/01

TCI Chemical

Product number: F0481
Product name: 3-Fluoro-p-cresol
Purity: >98.0%(GC)
Packaging: 5g
Price: $95
Updated: 2024/03/01

Alfa Aesar

Product number: H31864
Product name: 3-Fluoro-4-methylphenol, 97%
Packaging: 1g
Price: $107
Updated: 2021/12/16

Alfa Aesar

Product number: H31864
Product name: 3-Fluoro-4-methylphenol, 97%
Packaging: 5g
Price: $419
Updated: 2021/12/16

TRC

Product number: F597145
Product name: 3-Fluoro-4-methylphenol
Packaging: 100mg
Price: $45
Updated: 2021/12/16

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3-Fluoro-4-methylphenol Chemical Properties,Usage,Production

Uses

3-Fluoro-4-methylphenol is a phenolic derivative and can be used as a pharmaceutical intermediate.

Synthesis

3-Fluoro-4-methylaniline (5g, 39.95Immol) was dissolved in 10% sulfuric acid aqueous solution (100ml). Thereafter, the temperature was lowered to 0°C. thereto sodium nitrate (5.5g, 79.902mmol) was added, and the reaction mixture was stirred at same temperature for 30 minutes. Then the reaction mixture was stirred at 50°C for 30 minutes, and the last time, stirred at 80°C for 5 hours. Ice water was added to quench the reaction, and aqueous layer was extracted with ethyl acetate. Combined organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The residue was purified by column chromatography (n-hexane:ethyl acetate = 8:1) to give 2.26g (yield: 44.8%, colorless oil) of the target compound. 3-fluoro-4-methylphenol, yield 2.26g, 44.8% 1H NMR(400MHz, CDCl3): 6.98(1, J=8.6Hz, 1H), 6.52(m, 2H), 5.82(br, 1H), 2.12(s, 3H).

3-Fluoro-4-methylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Fluoro-4-methylphenol Suppliers

Americas 1 China 133 Europe 3 Germany 3 India 4 Italy 1 Japan 2 United Kingdom 17 United States 22 Global 186

Shandong Youfu Pharmaceutical Technology Co., Ltd.

Tel: +86-0536-8226195 +86-13953676784
Email: lee@unipharm-sd.com
Country: China
ProdList: 508
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Energy Chemical

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Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
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Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
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JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9984
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Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
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Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
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ProdList: 14113
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Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11660
Advantage: 64

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View Lastest Price from 3-Fluoro-4-methylphenol manufacturers

Unipharm pharmaceutical industry Co., Ltd

Product: 3-Fluoro-4-methylphenol 452-78-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: EX: 100kgs
Release date: 2021-03-23

Career Henan Chemical Co

Product: 3-FLUORO-4-METHYLPHENOL 452-78-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%~99%
Supply Ability: 1ton
Release date: 2019-12-18

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2-Fluoro-4-hydroxytoluene

3-FLUORO-4-METHYLPHENOL

3-FLUORO-P-CRESOL

3-Fluoro-p-cresol (OH=1)

3-Fluoro-4-methylphenol, JRD,

3-Fluoro-p-cresol&gt

Phenol, 3-fluoro-4-methyl-

452-78-8

Fluorine series

Aromatic Phenols

Phenol&Thiophenol&Mercaptan

Fluorine Compounds

Phenols