3-Fluoro-4-methylphenol
- Product Name
- 3-Fluoro-4-methylphenol
- CAS No.
- 452-78-8
- Chemical Name
- 3-Fluoro-4-methylphenol
- Synonyms
- 3-FLUORO-P-CRESOL;3-Fluoro-p-cresol>3-FLUORO-4-METHYLPHENOL;3-Fluoro-p-cresol (OH=1);2-Fluoro-4-hydroxytoluene;Phenol, 3-fluoro-4-methyl-;3-Fluoro-4-methylphenol, JRD,
- CBNumber
- CB1478242
- Molecular Formula
- C7H7FO
- Formula Weight
- 126.13
- MOL File
- 452-78-8.mol
3-Fluoro-4-methylphenol Property
- Melting point:
- 72 °C
- Boiling point:
- 196 °C
- Density
- 1.17
- refractive index
- 1.5150
- Flash point:
- 29 °C
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to lump
- pka
- 9.27±0.18(Predicted)
- color
- White to Light yellow to Light orange
- Odor
- Phenol-like
- InChI
- InChI=1S/C7H7FO/c1-5-2-3-6(9)4-7(5)8/h2-4,9H,1H3
- InChIKey
- GJOOCAXPERKNMN-UHFFFAOYSA-N
- SMILES
- C1(O)=CC=C(C)C(F)=C1
- CAS DataBase Reference
- 452-78-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 21/22-34-52-36-22
- Safety Statements
- 26-36/37/39-60-45
- RIDADR
- 2922
- Hazard Note
- Irritant
- HazardClass
- 8
- HS Code
- 29081990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H302Harmful if swallowed
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P309IF exposed or if you feel unwell:
P310Immediately call a POISON CENTER or doctor/physician.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- F0481
- Product name
- 3-Fluoro-p-cresol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $32
- Updated
- 2024/03/01
- Product number
- F0481
- Product name
- 3-Fluoro-p-cresol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $95
- Updated
- 2024/03/01
- Product number
- H31864
- Product name
- 3-Fluoro-4-methylphenol, 97%
- Packaging
- 1g
- Price
- $107
- Updated
- 2021/12/16
- Product number
- H31864
- Product name
- 3-Fluoro-4-methylphenol, 97%
- Packaging
- 5g
- Price
- $419
- Updated
- 2021/12/16
- Product number
- F597145
- Product name
- 3-Fluoro-4-methylphenol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
3-Fluoro-4-methylphenol Chemical Properties,Usage,Production
Uses
3-Fluoro-4-methylphenol is a phenolic derivative and can be used as a pharmaceutical intermediate.
Synthesis
3-Fluoro-4-methylaniline (5g, 39.95Immol) was dissolved in 10% sulfuric acid aqueous solution (100ml). Thereafter, the temperature was lowered to 0°C. thereto sodium nitrate (5.5g, 79.902mmol) was added, and the reaction mixture was stirred at same temperature for 30 minutes. Then the reaction mixture was stirred at 50°C for 30 minutes, and the last time, stirred at 80°C for 5 hours. Ice water was added to quench the reaction, and aqueous layer was extracted with ethyl acetate. Combined organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The residue was purified by column chromatography (n-hexane:ethyl acetate = 8:1) to give 2.26g (yield: 44.8%, colorless oil) of the target compound. 3-fluoro-4-methylphenol, yield 2.26g, 44.8% 1H NMR(400MHz, CDCl3): 6.98(1, J=8.6Hz, 1H), 6.52(m, 2H), 5.82(br, 1H), 2.12(s, 3H).
3-Fluoro-4-methylphenol Preparation Products And Raw materials
Raw materials
Preparation Products
3-Fluoro-4-methylphenol Suppliers
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View Lastest Price from 3-Fluoro-4-methylphenol manufacturers
- Product
- 3-Fluoro-4-methylphenol 452-78-8
- Price
- US $40.00-20.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-08-05
- Product
- 3-Fluoro-4-methylphenol 452-78-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- EX: 100kgs
- Release date
- 2021-03-23
- Product
- 3-FLUORO-4-METHYLPHENOL 452-78-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%~99%
- Supply Ability
- 1ton
- Release date
- 2019-12-18