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BENZOFURAN-5-BORONIC ACID

Product Name
BENZOFURAN-5-BORONIC ACID
CAS No.
331834-13-0
Chemical Name
BENZOFURAN-5-BORONIC ACID
Synonyms
Akos ba-183;AKOS BRN-0183;ENZOFURAN-5-BORONIC ACID;BENZOFURAN-5-BORONIC ACID;5-Benzofuranylboronic acid;1-Benzofuran-5-boronic acid;Benzofuran-5-ylboronic acid;1-benzofuran-5-ylboronicaci;(4)BENZOFURAN-5-BORONIC ACID;Benzo[b]furan-5-boronic acid
CBNumber
CB1488250
Molecular Formula
C8H7BO3
Formula Weight
161.95
MOL File
331834-13-0.mol
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BENZOFURAN-5-BORONIC ACID Property

Boiling point:
340.4±34.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
form 
solid
pka
8.25±0.30(Predicted)
color 
White to off-white
InChI
InChI=1S/C8H7BO3/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5,10-11H
InChIKey
WYXQQAYIAJRORT-UHFFFAOYSA-N
SMILES
B(C1=CC=C2OC=CC2=C1)(O)O
CAS DataBase Reference
331834-13-0(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Hazard Note 
Corrosive
HS Code 
2932990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
B207698
Product name
Benzofuran-5-boronicacid
Packaging
250mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB139686
Product name
Benzofuran-5-ylboronic acid
Packaging
50mg
Price
$63
Updated
2021/12/16
SynQuest Laboratories
Product number
6H60-1-V2
Product name
Benzo[b]furan-5-boronic acid
Packaging
1g
Price
$264
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB139686
Product name
Benzofuran-5-ylboronic acid
Packaging
500mg
Price
$280
Updated
2021/12/16
Matrix Scientific
Product number
145332
Product name
Benzofuran-5-ylboronic acid
Purity
95%
Packaging
1g
Price
$315
Updated
2021/12/16
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BENZOFURAN-5-BORONIC ACID Chemical Properties,Usage,Production

Synthesis

23145-07-5

121-43-7

331834-13-0

The general procedure for the synthesis of benzo[b]furan-5-boronic acid from 5-bromobenzo[b]furan and trimethyl borate is as follows: 1. a hexane solution of n-butyllithium (1.5 M; 3.72 ml, 5.6 mmol) was slowly added dropwise to a solution of tetrahydrofuran (10 ml) of 5-bromobenzo[b]furan (1.0 g, 5.0 mmol) under argon protection, keeping the reaction temperature at -60°C. 2. stirring was continued at the same temperature for 30 min. 3. trimethyl borate (0.69 ml, 6.0 mmol) was added to the reaction system, followed by slow warming of the reaction mixture to room temperature over a period of 4 hours. 4. Water (5 ml) was added to the reaction mixture and cooled to 5 °C, followed by distillation under reduced pressure to remove the tetrahydrofuran. 5. The pH was adjusted to 1 by adding 1N hydrochloric acid to the residue and then extracted with ethyl acetate. 6. The organic layer was washed with brine, dried and the solvent was removed by distillation. 7. The residue was ground with hexane/ether mixture, filtered and dried to give benzo[b]furan-5-boronic acid (551 mg) in light brown solid form.

References

[1] Patent: EP2959918, 2015, A1. Location in patent: Paragraph 0089

BENZOFURAN-5-BORONIC ACID Preparation Products And Raw materials

Raw materials

SEC-BUTYLLITHIUM Trimethyl borate Nitrogen N,N-Dimethylformamide Potassium iodide Tributyl borate Toluene Bromoacetaldehyde diethyl acetal Potassium carbonate Polyphosphoric acid Tetrahydrofuran Bromoacetaldehyde dimethyl acetal 4-Bromophenol Chlorobenzene Ethyl acetate Hydrochloric acid Sodium bicarbonate Cyclopentanone Magnesium sulfate PETROLEUM ETHER n-Butyllithium

Preparation Products

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BENZOFURAN-5-BORONIC ACID Suppliers

China 80 France 1 Germany 2 India 2 Russia 1 United Kingdom 6 United States 15 Global 107
Huzhou Chenghong Biotechnology Co., Ltd.
Tel
13626726938
Email
13626726938@163.cn
Country
China
ProdList
330
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Tetranov Biopharm
Tel
13526569071
Email
sales@leadmedpharm.com
Country
China
ProdList
7892
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Changzhou Chemscaler Pharmtech Co., Ltd.
Tel
0519-81096292 15312577869
Email
chemscaler@yahoo.com.cn
Country
China
ProdList
311
Advantage
60
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
42446
Advantage
60
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View Lastest Price from BENZOFURAN-5-BORONIC ACID manufacturers

Career Henan Chemical Co
Product
BENZOFURAN-5-BORONIC ACID 331834-13-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-08
Nanjing jinheyou Trading Co., Ltd.
Product
BENZOFURAN-5-BORONIC ACID 331834-13-0
Price
US $0.00/g
Min. Order
1g
Purity
95%min
Supply Ability
20kg/month
Release date
2019-12-23
Nanjing jinheyou Trading Co., Ltd.
Product
BENZOFURAN-5-BORONIC ACID 331834-13-0
Price
US $0.00/g
Min. Order
1g
Purity
95%min
Supply Ability
20kg/month
Release date
2019-12-20

331834-13-0, BENZOFURAN-5-BORONIC ACIDRelated Search:

pyrido[3,2-d]pyridazin-8(7H)-one benzo[b]thiophene-4-ol 1-benzothiophen-4-aMine Dibenzofuran 1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID Benzofuro[3,2-d]pyriMidine-2,4(1H,3H)-dione 4-Benzothiazolecarboxaldehyde Benzothiazole-5-carboxylic acid 2-(BENZOFURAN-2-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan Benzofuran-7-boronic acid BENZOFURAN-2-BORONIC ACID,Benzofuran-2-boronic Acid (contains varying amounts of Anhydride) 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1-BENZOFURAN BENZOFURAN-3-BORONIC ACID DIBENZOFURAN-4-BORONIC ACID BENZOFURAN-2,5-DIYLDIBORONIC ACID 98 BENZOFURAN-5-BORONIC ACID 2,3-DIHYDRO-1-BENZOFURAN-7-BORONIC ACID

  • 5-Benzofuranylboronic acid
  • Boronic acid, B-5-benzofuranyl-
  • 1-Benzofuran-5-boronic acid, 5-Borono-1-benzofuran
  • ENZOFURAN-5-BORONIC ACID
  • BENZOFURAN-5-BORONIC ACID
  • AKOS BRN-0183
  • Akos ba-183
  • benzofuran-5-yl-5-boronic acid
  • Benzo[b]furan-5-boronic acid
  • (4)BENZOFURAN-5-BORONIC ACID
  • 1-Benzofuran-5-boronic acid
  • (1-benzofuran-5-yl)boronic acid
  • Benzofuran-5-ylboronic acid
  • 1-benzofuran-5-ylboronicaci
  • Benzofuran-5-boronic acid (contains varying amounts of Anhydride)
  • 331834-13-0
  • C8H7BO3