1H-Benzimidazole-4-carboxylic acid

Product Name: 1H-Benzimidazole-4-carboxylic acid
CAS No.: 46006-36-4
Chemical Name: 1H-Benzimidazole-4-carboxylic acid
Synonyms: 4-Carboxy-1H-benzimidazole;Benzimidazole-4-carboxylicacid;4-Benzimidazolecarboxylic acid;1H-BENZIMIDAZOLE-4-CARBOXYLIC ACID;1,3-Benzodiazole-4-carboxylic acid;1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID;benzimidazole-4-carboxylic acid HCl;1H-Benzimidazole-4-carboxylicacid97%;1H-benzo[d]imidazol-7-carboxylic acid;1H-1,3-benzodiazole-4-carboxylic acid
CBNumber: CB7164877
Molecular Formula: C8H6N2O2
Formula Weight: 162.15
MOL File: 46006-36-4.mol

More

Less

1H-Benzimidazole-4-carboxylic acid Property

Melting point:: >300 °C
Boiling point:: 542.5±23.0 °C(Predicted)
Density: 1.506±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 0.17±0.10(Predicted)
Appearance: Off-white to light brown Solid

More

Less

Safety

Hazard Codes: Xi,N
Risk Statements: 36-51
Safety Statements: 53-26-61
RIDADR: UN 3077 9 / PGIII
HazardClass: IRRITANT
HS Code: 29339980

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B197883
Product name: 1H-Benzimidazole-4-carboxylicAcid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B197883
Product name: 1H-Benzimidazole-4-carboxylicAcid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 027337
Product name: 1H-Benzimidazole-4-carboxylic acid
Packaging: 1g
Price: $79
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB05897
Product name: Benzimidazole-4-carboxylic acid
Packaging: 1g
Price: $87.5
Updated: 2021/12/16

AK Scientific

Product number: W6385
Product name: 1H-Benzimidazole-7-carboxylicacid
Packaging: 250mg
Price: $104
Updated: 2021/12/16

More

Less

1H-Benzimidazole-4-carboxylic acid Chemical Properties,Usage,Production

Synthesis

64-18-6

603-81-6

46006-36-4

To a 4M hydrochloric acid (20 mL) solution of formic acid (0.75 mL, 20.0 mmol) was added 2,3-diaminobenzoic acid (1.00 g, 6.6 mmol). The reaction mixture was heated at reflux temperature for 2 h and subsequently cooled to room temperature. The resulting pink precipitate was separated by filtration and dissolved in hot methanol. Decolorization was carried out by adding activated carbon and stirring for 10 min. The suspension was filtered and the solvent was evaporated under reduced pressure to afford benzimidazole-7-carboxylic acid (0.542 g, 51% yield) as white crystals with a melting point of 266-268 °C. The structure of the product was analyzed by 1H NMR (300 MHz, DMSO-d6) δ 9.64 (s, 1H), 8.11 (dd, J = 8.2, 0.9 Hz, 1H), 8.07 (dd, J = 7.6, 0.9 Hz, 1H), 7.65 (dd, J = 8.2, 7.6 Hz, 1H) and 13C NMR (75 MHz, DMSO-d6 ) δ 265.2, 142.0, 132.3, 129.3, 127.6, 125.6, 119.7, 117.6 confirmed.

References

[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 22, p. 4084 - 4097
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 14, p. 3933 - 3937
[3] Chemische Berichte, 1901, vol. 34, p. 905
[4] Patent: WO2018/42362, 2018, A1. Location in patent: Page/Page column 50

1H-Benzimidazole-4-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1H-Benzimidazole-4-carboxylic acid Suppliers

China 120 Europe 1 France 2 Germany 2 Hungary 1 India 3 Russia 1 United Kingdom 6 United States 23 Global 159

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-021-61259138 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Carbott PharmTech Inc.

Tel: 0535-6385396
Fax: +86 (535) 638-9971
Email: info@carbottpharm.com
Country: China
ProdList: 959
Advantage: 56

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11036
Advantage: 64

ZEROSCHEM.CO.,LTD.

Tel: 10-61256048 13810278579
Fax: +86 10 61256049
Email: sales@zeroschem.com
Country: China
ProdList: 1368
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 14873
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

More

Less

View Lastest Price from 1H-Benzimidazole-4-carboxylic acid manufacturers

Career Henan Chemical Co

Product: 1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID 46006-36-4
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2020-03-23

46006-36-4, 1H-Benzimidazole-4-carboxylic acidRelated Search:

4-Benzothiazolamine (9CI) 1H-Benzimidazole-2-carboxaldehyde Benzocyclobutyl-1-carboxylic acid Azilsartan Trityl candesartan cilexetil Ethyl-2-Ethoxy-1-[[(2'-(1h-Tetrazol-5-Yl)Biphenyl-4-Yl)Methyl]Benzimidazole]-7-Carboxylate 1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID 2-ethoxy-3-[[4-[2-(1h-tetrazol-5-yl)phenyl]phenyl]methyl]-3h-benzoimidazole-4-carboxylic acid 1H-BENZIMIDAZOLE-2-CARBOXYLIC ACID HYDRATE 1H-Benzimidazole-6-carboxylicacid,1-methyl-(9CI) 2-PHENYL-3H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID Ethyl 1-methyl-1H-benzimidazole-5-carboxylate 2-PYRIDIN-4-YL-3H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate 1-Methyl-1H-benzimidazole-5-carboxylic acid 2-Methylbenzimidazole-5-carboxylic acid 1H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID

Benzimidazole-4-carboxylicacid

1H-Benzimidazole-4-carboxylic acid 97%

1H-Benzimidazole-4-carboxylicacid(9CI)

4-Benzimidazolecarboxylic acid

4-Carboxy-1H-benzimidazole

1H-benzo[d]iMidazole-7-carboxylic acid

1H-1,3-benzodiazole-4-carboxylic acid

1H-benzo[d]imidazol-7-carboxylic acid

1H-Benzimidazole-4-carboxylicacid97%

1H-BENZIMIDAZOLE-4-CARBOXYLIC ACID

1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID

1H-benzo[d]imidazole-4-carboxylic acid

1,3-Benzodiazole-4-carboxylic acid

benzimidazole-4-carboxylic acid HCl

46006-36-4

46006-36-7

Benzoimidazole

Building Blocks

BENZIMIDAZOLE

pharmacetical

Carboxylic Acids

Imidazoles & Benzimidazoles

Carboxylic Acids

Imidazoles & Benzimidazoles