4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid

Product Name: 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid
CAS No.: 152628-03-0
Chemical Name: 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid
Synonyms: 4-METHYL-2-PROPYL-1H-BENZIMIDAZOLE-6-CARBOXYLIC ACID;2-N-PROPYL-4-METHYL-6-CARBOXY-BENZIMIDAZOLE;Single-imidazole;2-N-Propyl-4-Meth;Telmisartan Intermediate 3;BENZIMIDAZOLE CARBOXYLIC ACID;TelMisartan BenziMidazole Acid;Telmisartan Benzimidazole Acid Impurity;6-Carboxy-4-methyl-2-propylbenzimidazole;4-METHYL-2-PROPYL-6-CARBOXYL BENZIMIDAZOLE
CBNumber: CB2133083
Molecular Formula: C12H14N2O2
Formula Weight: 218.25
MOL File: 152628-03-0.mol

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4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid Property

Melting point:: 300 °C
Boiling point:: 491.8±25.0 °C(Predicted)
Density: 1.259±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO, Methanol
pka: 3.19±0.30(Predicted)
form: Powder
color: Pale Yellow to Tan
InChIKey: XWAJTVCEILFDGU-UHFFFAOYSA-N
CAS DataBase Reference: 152628-03-0(CAS DataBase Reference)

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Safety

HS Code: 29332900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2000
Product name: 4-Methyl-2-propyl-6-benzimidazolecarboxylic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $60
Updated: 2025/07/31

Usbiological

Product number: B1062
Product name: 1H-Benzimidazole-6-carboxylic-4-methyl-2-propyl
Packaging: 1g
Price: $403
Updated: 2021/12/16

TRC

Product number: B197825
Product name: 1H-Benzimidazole-4-methyl-2-propyl-6-carboxylicAcid
Packaging: 5g
Price: $440
Updated: 2021/12/16

Chem-Impex

Product number: 42588
Product name: 4-Methyl-2-propyl-6-benzimidazolecarboxylicacid,≥98%(HPLC)
Purity: ≥98%(HPLC)
Packaging: 5G
Price: $50.85
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB18198
Product name: 1H-Benzimidazole-4-methyl-2-propyl-6-carboxylic acid
Packaging: 1g
Price: $60
Updated: 2021/12/16

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4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Light Yellow to Tan Powder

Uses

4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid is a useful synthetic intermediate,a useful compound in organic synthesis.

Synthesis

152628-01-8

152628-03-0

Example 4: Methyl 3-methyl-4-butyrylamino-5-nitrobenzoate (II) (10 g, 0.036 mol) was suspended in 60 ml of water and heated to 70-80 °C. A suspension of sodium dithionite (21.75 g, 0.124 mol) in 60 ml of water was added slowly and heated to 90-100 °C. Upon completion of the reaction, the pH of the reaction mixture was adjusted to 10-11 and the temperature was maintained with continued stirring until TLC detection showed complete disappearance of methyl 3-methyl-4-butyrylamino-5-nitrobenzoate. Subsequently, the pH of the reaction mixture was adjusted to 6-6.5. The resulting solid was filtered and dried at 45-50 °C to afford 2-n-propyl-4-methyl-6-carboxybenzimidazole (7.5 g, yield: 96.4%).

References

[1] Patent: WO2012/28925, 2012, A2. Location in patent: Page/Page column 18
[2] Journal of Heterocyclic Chemistry, 2003, vol. 40, # 6, p. 1107 - 1112
[3] Journal of Medicinal Chemistry, 1993, vol. 36, # 25, p. 4040 - 4051
[4] Patent: WO2012/28925, 2012, A2
[5] Organic Process Research and Development, 2007, vol. 11, # 1, p. 81 - 85

4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid Preparation Products And Raw materials

Raw materials

3-Methyl-4-nitrobenzoic acid Nickel Hydrazine hydrate Triethylamine Butyryl chloride Nitric acid Acetic acid Methanol Sulfuric acid

Preparation Products

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4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid Suppliers

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View Lastest Price from 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid 152628-03-0
Price: US $25.00/ASSAYS
Min. Order: 100ASSAYS
Purity: 99.5%
Supply Ability: 100 mt
Release date: 2024-11-19

Henan Aochuang Chemical Co.,Ltd.

Product: 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid 152628-03-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

Shaanxi Haibo Biotechnology Co., Ltd

Product: 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid 152628-03-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-28

152628-03-0, 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acidRelated Search:

Propyl gallate Methyl salicylate N,N-Dimethylallylamine 3-Methyl-2-butanone Benzimidazole Cyclopropyl methyl ketone Isopropyl alcohol Propyl butyrate 2-Methylbenzimidazole Methyl 4-(butyrylamino)-3-methyl-5-nitrobenzoate ALLYL METHYL ETHER Methyl 4'-bromomethyl biphenyl-2-carboxylate tert-Butyl 4'-(bromomethyl)biphenyl-2-carboxylate Thiophanate-methyl Methyl 2-METHYLPENTANE Methyl bromide 1H-Benzimidazole-5-carboxylic acid

4-METHYL-2-N-PROPYL-1H-BENZIMIDAZOLE-6-CARBOXYLIC ACID

4-METHYL-2-PROPYL-1H-BENZIMIDAZOLE-6-CARBOXYLIC ACID

4-METHYL-2-PROPYL-6-CARBOXYL BENZIMIDAZOLE

2-N-PROPYL-4-METHYL-6-CARBOXY-BENZIMIDAZOLE

2-N-PROPYL-4-METHYLBENZIMIDAZOLE-6-CARBOXYLIC ACID

2-PROPYL-4-METHYL-6-CARBOXYL BENZIMIDAZOLE

Telmisartan Intermediate 3

2-N-Propyl-4-Meth

6-Carboxy-4-methyl-2-propylbenzimidazole

1H-Benzimidazole-4-methyl-2-propyl-6-carboxylic Acid

4-Methyl-2-Propyl-1h-Benzimidazole-6-Carboxyboxylic Acid

1H-BENZIMIDAZOLE-6-CARBOXYLIC-4-METHYL-2-PROPYL

4-Methyl-2-Propyl-1H-Benzimidazole-6-CarboxylicAcid[TelmisartanIntermediates]

2-N-Propyl-4-Methyl-6-Carbony-Benzimidazole

2-PROPYL-4-METHYL-1H-BENZIMIDAZOLE-6-CARBOXYLICACID

1H-Benzimidazole-5-carboxylic acid, 7-methyl-2-propyl,

1H-Benzimidazol-5-carbonsure, 7-methyl-2-propyl-

4-METHYL-2-PROPYL-6-BENZIMIDAZOLECARBOXYLIC ACID

2-n-Propyl-4-Methyl-6-Carboxylate-1H-Benzimidazole

7-methyl-2-propyl-3H-benzo[d]imidazole-5-carboxylic acid

4-Methyl-2-propyl-1H-1,3-benzodiazole-6-carboxylic acid

2-n-propyl-4-Methyl-6-carboxy-benziMidazole 3

4-Methyl-2-propyl-1H-benzo[d]iMidazole-6-carboxylic acid

TelMisartan BenziMidazole Acid

2-n-propyl-1H-benzimidazole-6-carboxylic acid

Single-imidazole

7-methyl-2-propyl-3aH-benzimidazole-5-carboxylic acid

Telmisartan Benzimidazole Acid Impurity

4-Methyl-2-propyl-6-benzimidazolecarboxylicAcid&gt

2-propyl-4-methyl-benzimidazole-6-carboxylic acid

Telmisartan Benzimidazole AcidQ: What is Telmisartan Benzimidazole Acid Q: What is the CAS Number of Telmisartan Benzimidazole Acid Q: What is the storage condition of Telmisartan Benzimidazole Acid Q: What are the applications of Telmisartan Benzimidazole Acid

4-Methyl-2-n-propyl-6-carboxylic benzimidazole

4-Methyl-2-n-propyl-1H-benzimidazoIe-6-carbox

4-Methyl-2-Propylbenzimidazole-6-Carboxylic Acid

BENZIMIDAZOLE CARBOXYLIC ACID

7-methyl-2-propaneyl-(1H)-benzoimidazole-5-carboxylic acid

4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylicacid (BIM-I)

2-Propyl-4-methyl-6-carboxylic benzimidazole

7-Methyl-2-propyl-1H-benzo[d]imidazol-5-carboxylic acid

152628-03-0

1526280-03-0

Heterocycles

Imidazoles

Aromatics

INTERMEDIATESOF

Imidazol&Benzimidazole