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4-Formylphenylboronic acid

Product Name
4-Formylphenylboronic acid
CAS No.
87199-17-5
Chemical Name
4-Formylphenylboronic acid
Synonyms
FPBA;4-FORMYLBENZENEBORONIC ACID;AKOS BRN-0111;TIMTEC-BB SBB004077;RARECHEM AH PB 0193;4-Formylboronic acid;4-BORONOBENZALDEHYDE;4-Formylphenylboroni;Metoprolol Impurity 34;Formylphenylboronic acid
CBNumber
CB1491072
Molecular Formula
C7H7BO3
Formula Weight
149.94
MOL File
87199-17-5.mol
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4-Formylphenylboronic acid Property

Melting point:
237-242 °C (lit.)
Boiling point:
347.6±44.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
vapor pressure 
0Pa at 25℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
<10g/l
pka
7.34±0.10(Predicted)
form 
Liquid
color 
Clear colorless to yellow-orange
PH
5.5 (1g/l, H2O, 20℃)
Water Solubility 
Slightly Soluble in water.
Sensitive 
Air Sensitive
BRN 
3030770
InChIKey
VXWBQOJISHAKKM-UHFFFAOYSA-N
LogP
1.36 at 20℃
CAS DataBase Reference
87199-17-5(CAS DataBase Reference)
EPA Substance Registry System
Boronic acid, (4-formylphenyl)- (87199-17-5)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
34-36/37/38
Safety Statements 
22-26-36/37/39-45-37/39-36
RIDADR 
UN 1759 8/PG 3
WGK Germany 
3
10
Hazard Note 
Irritant
TSCA 
T
HazardClass 
IRRITANT, AIR SENSITIVE
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
431966
Product name
4-Formylphenylboronic acid
Purity
≥95.0%
Packaging
1g
Price
$35.4
Updated
2024/03/01
Sigma-Aldrich
Product number
431966
Product name
4-Formylphenylboronic acid
Purity
≥95.0%
Packaging
5g
Price
$117
Updated
2024/03/01
TCI Chemical
Product number
F0446
Product name
4-Formylphenylboronic Acid (contains varying amounts of Anhydride)
Packaging
1g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
F0446
Product name
4-Formylphenylboronic Acid (contains varying amounts of Anhydride)
Packaging
5g
Price
$77
Updated
2024/03/01
Alfa Aesar
Product number
B25199
Product name
4-Formylbenzeneboronic acid, 97%
Packaging
1g
Price
$33.65
Updated
2024/03/01
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4-Formylphenylboronic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

suzuki reaction

Uses

4-Formylbenzeneboronic acid acts as a reagent used for Palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water, copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides, ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids, triethylamine-catalyzed three-component Hantzsch condensations, copper-catalyzed nitrations, oxidative mono-cleavage of dialkenes catalyzed by Trametes hirsuta, palladacycle-catalyzed cross-coupling of arylboronic acids with carboxylic anhydrides or acyl chlorides, palladium-catalyzed aerobic oxidative cross-coupling reactions. It acts as a reagent used in preparation of sensitizers with dithiafulvenyl unit as electron donor for high-efficiency dye-sensitized solar cells, a novel protein synthesis inhibitor active against Gram-positive bacteria.

Uses

4-Formylphenylboronic acid is a substrate for Suzuki cross-coupling reactions and it can be used as a reagent for:

  • Palladium-catalyzed Suzuki-Miyaura cross-coupling in water.
  • Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides.
  • Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids.
  • Triethylamine-catalyzed three-component Hantzsch condensations.
  • Copper-catalyzed nitrations.
  • Oxidative mono-cleavage of dialkenes catalyzed by Trametes hirsuta.
  • Palladacycle-catalyzed cross-coupling of arylboronic acids with carboxylic anhydrides or acyl chlorides.
  • Palladium-catalyzed aerobic oxidative cross-coupling reactions.
  • The synthesis of sensitizers with dithiafulvenyl unit as electron donor for high-efficiency dye-sensitized solar cells.
  • The synthesis of a novel protein synthesis inhibitor active against Gram-positive bacteria.
  • The Suzuki aryl-aryl coupling of the upper rim of hexahomotrioxacalix[3]arene.
  • A rhodium-catalyzed cyclization, converting 1,5-enynes to cyclopentenes and spiro-cyclopentenes.

Flammability and Explosibility

Not classified

Synthesis

Potassium phenyltrifluoroborate (184 mg, 1.00 mmol) was added to a solution of iron trichloride (185 mg, 1.10 mmol) in 3 mL of 1:1 THF/water. The mixture was stirred at room temperature for 30 min. The reaction mixture was then passed through a short column containing neutral absorption alumina. The alumina was then washed with a mixture of ethyl acetate/hexanes (2:1) to obtain 4-Formylphenylboronic acid (105 mg, 86%). [The boronic acid products can also be isolated by simple extraction techniques.]

4-Formylphenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Formylphenylboronic acid Suppliers

Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9346
Advantage
58
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
China Synchem Technology Co.,Ltd.
Tel
+86-0552-4929304 +86-18055277008
Fax
+86-552-4928800
Email
sales@cnsynchem.com
Country
China
ProdList
57
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65
Wuhan kemike Biomedical Technology Co., Ltd
Tel
027-87747081 18186681184
Email
1344475572@qq.com
Country
China
ProdList
7235
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58
Hebei Maison Chemical Co.,Ltd.
Tel
0311-85381176 15511852758
Fax
0311-83832777
Email
ruby@maisonchem.com.cn
Country
China
ProdList
545
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58
Changzhou Zeyuan Pharmaceutical Technology Co., Ltd
Tel
19026388314
Email
2589694173@qq.com
Country
China
ProdList
144
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
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View Lastest Price from 4-Formylphenylboronic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
4-Formylphenylboronic acid 87199-17-5
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-20
HebeiShuoshengImportandExportco.,Ltd
Product
4-Formylphenylboronic acid 87199-17-5
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-09
Hebei Longbang Technology Co., Ltd
Product
4-Formylphenylboronic acid 87199-17-5
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-04-28

87199-17-5, 4-Formylphenylboronic acidRelated Search:


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  • Metoprolol Impurity 34
  • Formylphenylboronic acid
  • 87199-17-5
  • 87199-17-2
  • Boronic Acids
  • B (Classes of Boron Compounds)
  • BORONIC ACID
  • Boronic Acids and Derivatives
  • Aryl
  • Organometallic Reagents
  • Substituted Boronic Acids
  • Boron, Nitrile, Thio,& TM-Cpds
  • Carbonyl Compounds
  • ALDEHYDE
  • Aldehydes
  • blocks
  • BoronicAcids
  • Boronic Acid series
  • Aryl
  • Organoborons
  • B (Classes of Boron Compounds)
  • CHIRAL CHEMICALS
  • Boronic Acids & Esters