ChemicalBook > CAS DataBase List > N-Isopropylacrylamide

N-Isopropylacrylamide

Product Name
N-Isopropylacrylamide
CAS No.
2210-25-5
Chemical Name
N-Isopropylacrylamide
Synonyms
NIPAM;NIPAAm;acryL;Isopropyl acrylamide;N-isopropylacrylamide ,99%;N-(1-methylethyl)-2-Propenamide;FITC-PEG;AKOS 91289;N-IsopropyL;polyNIPAM-BA
CBNumber
CB1494912
Molecular Formula
C6H11NO
Formula Weight
113.16
MOL File
2210-25-5.mol
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N-Isopropylacrylamide Property

Melting point:
60-63 °C(lit.)
Boiling point:
89-92 °C2 mm Hg(lit.)
Density 
1.0223 (rough estimate)
refractive index 
1.4210 (estimate)
storage temp. 
2-8°C
form 
Crystalline Powder or Crystals
pka
14.83±0.46(Predicted)
color 
White to light yellow
PH
pH(50g/l, 25℃) : 7.8～10.0
Water Solubility 
Slightly soluble in water.
InChIKey
QNILTEGFHQSKFF-UHFFFAOYSA-N
LogP
0.278 (est)
CAS DataBase Reference
2210-25-5(CAS DataBase Reference)
NIST Chemistry Reference
Acrylamide, n-isopropyl-(2210-25-5)
EPA Substance Registry System
2-Propenamide, N-(1-methylethyl)- (2210-25-5)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36-36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
RTECS 
AS3675000
TSCA 
Yes
HS Code 
29241990
Hazardous Substances Data
2210-25-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
415324
Product name
N-Isopropylacrylamide
Purity
97%
Packaging
10g
Price
$47.2
Updated
2024/03/01
Sigma-Aldrich
Product number
415324
Product name
N-Isopropylacrylamide
Purity
97%
Packaging
50g
Price
$166
Updated
2024/03/01
TCI Chemical
Product number
I0401
Product name
N-Isopropylacrylamide (stabilized with MEHQ)
Purity
>98.0%(GC)
Packaging
25g
Price
$54
Updated
2024/03/01
TCI Chemical
Product number
I0401
Product name
N-Isopropylacrylamide (stabilized with MEHQ)
Purity
>98.0%(GC)
Packaging
100g
Price
$99
Updated
2024/03/01
Alfa Aesar
Product number
H66262
Product name
N-Isopropylacrylamide, 97%
Packaging
25g
Price
$74.2
Updated
2024/03/01
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N-Isopropylacrylamide Chemical Properties,Usage,Production

Description

N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties, which include temperature-based volumetric and phase changes. These properties change when the temperature of the solution reaches a lower critical solution temperature (LCST).

Chemical Properties

white to light yellow crystalline powder or

Uses

NIPAM can be used to prepare poly(NIPAM) for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration.

Uses

Binders in textiles, paper, adhesives, detergents, cosmetics.
N-Isopropylacrylamide is used to produce poly(N-isopropylacrylamide) (pNIPA, pNIPAAm, pNIPAA or pNIPAm) thermo sensitive polymer- or copolymer-based hydrogels. Polymers that contain NIPAM shrink dramatically above 33°C. Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.

Application

N-Isopropylacrylamide (NIPAM) can be used to prepare poly(NIPAM) based thermosetting polymers, which can be used for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration.
Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.

General Description

N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties. These properties include temperature based volumetric and phase changes, which change when the temperature of the solution reaches a lower critical solution temperature (LCST).

Flammability and Explosibility

Not classified

Purification Methods

Fractionate the amide under reduced pressure, and recrystallise the solid distillate from hexane (m 59o), *C6H6 (m 62o) or *C6H6/hexane (m 62-63o). Store it with 0.05% of 4-tert-butylcatechol. It is used for making water soluble swellable hydrogels. [Beilstein 4 IV 517.]

N-Isopropylacrylamide Preparation Products And Raw materials

Raw materials

FUMING SULFURIC ACID 4-tert-Butylcatechol Ethyl 2-(Chlorosulfonyl)acetate Sodium sulfate Sodium chloride Acryloyl chloride Triethylamine Diisopropylamine Hydroquinone Tetrahydrofuran 1,4-Dimethoxybenzene Ethyl acetate Dichloromethane 4-Methoxyphenol Acetic acid Sodium hydroxide Acrylonitrile Isopropyl alcohol Isopropylamine PETROLEUM ETHER Sulfuric acid

Preparation Products

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View Lastest Price from N-Isopropylacrylamide manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
N-Isopropylacrylamide 2210-25-5
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-09
Hebei Chuanghai Biotechnology Co,.LTD
Product
N- (1-methylethyl) -2-Propenamide 2210-25-5
Price
US $19.00-19.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2024-08-23
WUHAN FORTUNA CHEMICAL CO., LTD
Product
N-Isopropylacrylamide (NIPAM) 2210-25-5
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
98%min
Supply Ability
15tons/month
Release date
2021-06-03

2210-25-5, N-IsopropylacrylamideRelated Search:

N,N'-Methylenebisacrylamide Cocamidopropyl betaine Methacrylamide Acrylamide N-Hydroxyphthalimide CAPRYLOHYDROXAMIC ACID N-Cyclohexylmaleimide Bromacil N-TERT-BUTYLACRYLAMIDE N-TERT-OCTYLACRYLAMIDE Actinomycin D Terbacil N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine Diacetone acrylamide Lenacil 2-Acrylamide-2-methylpropanesulfonic acid Poly[[N-isopropylacrylamide-co-[N-[3-(dodecyldimethylammonio)propyl]acrylamide]]phosphotungstate] POLY(N-ISOPROPYL ACRYLAMIDE)

  • N-isopropylacrylamide ,99%
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  • -PropenaMide, N-(1-Methylethyl)-
  • N-IsopropylacrylaMide&nbsp
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  • N-IsopropylacrylaMide, 99%, stabilized with 500 ppM MEHQ
  • N-IsopropylacrylaMide, stabilized with 500 ppM MEHQ
  • AKOS 91289
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  • N-ISOPROPYLACRYLAMIDE
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  • Isopropylamid kyseliny akrylove
  • isopropylamidkyselinyakrylove
  • n-(1-methylethyl)-2-propenamid
  • acryL
  • N-IsopropyL
  • Acrylamide, N-isopropyl.
  • N-Isopropylacrylamide ,99% [pure,stabilized]
  • N-ISOPROPYLACRYLAMIDE, 99%, STABILIZED, PURE
  • N-Isopropylacrylamide, stabilized, pure, 99%
  • NIPAAm
  • n-isopropylacrylamide ,98% [pure,stabilized]
  • N-(1-methylethyl)-2-Propenamide
  • n-isopropyl-acrylamid
  • N-Isopropylacrylamide, 98%, stabilized with 500 ppm MEHQ
  • N-Isopropylacrylamide (stabilized with MEHQ)&gt
  • N-Isopropylacrylamide, 99%, reagent grade, stabilized with 500 ppm MEHQ
  • N-Isopropylacrylamide (NIPAM)
  • N-IsopropylacrylaMide -PropenaMide
  • N-Isopropylacrylamide (NIPAM) extrapure, 99%
  • FITC-PEG
  • N-Isopropylacrylamide (sabilized wih MEHQ), 98%
  • Alflutinib Impurity 7
  • N-lsopropylacrylamide
  • 2210-25-5
  • H2CCHCONHCHCH32
  • AMINE
  • Acrylamide and Methacrylamide
  • Acrylic Monomers
  • Monomers