DROFENINE HYDROCHLORIDE
- Product Name
- DROFENINE HYDROCHLORIDE
- CAS No.
- 548-66-3
- Chemical Name
- DROFENINE HYDROCHLORIDE
- Synonyms
- it-19;trasentinh;DrofeninHCl;DROFENINE HCL;cyclovegantine;cycloadiphenine;hexahydroadiphenine;Drofeninhydrochlorid;LABOTEST-BB LT00244841;DROFENINE HYDROCHLORIDE
- CBNumber
- CB1496239
- Molecular Formula
- C20H32ClNO2
- Formula Weight
- 353.93
- MOL File
- 548-66-3.mol
DROFENINE HYDROCHLORIDE Property
- Melting point:
- 145-147°
- storage temp.
- 2-8°C
- solubility
- Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
- form
- Solid
- color
- White to Off-White
Safety
- WGK Germany
- 2
- RTECS
- GU6825000
- Toxicity
- LD50 i.v. in mice: 65.6 mg/kg (Fleisch)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H332Harmful if inhaled
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D679000
- Product name
- DrofenineHydrochloride
- Packaging
- 1g
- Price
- $1020
- Updated
- 2021/12/16
- Product number
- API0012869
- Product name
- DROFENINE HYDROCHLORIDE
- Purity
- 98.00%
- Packaging
- 500G
- Price
- $4866.02
- Updated
- 2021/12/16
- Product number
- CS-4885
- Product name
- Drofeninehydrochloride
- Purity
- 98.10%
- Packaging
- 50mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- B876
- Product name
- Drofeninehydrochloride
- Packaging
- 1g
- Price
- $127
- Updated
- 2021/12/16
- Product number
- API0012869
- Product name
- DROFENINE HYDROCHLORIDE
- Purity
- 98.00%
- Packaging
- 10MG
- Price
- $280.35
- Updated
- 2021/12/16
DROFENINE HYDROCHLORIDE Chemical Properties,Usage,Production
Originator
Trasentine A,Ciba
Uses
Spasmolytic
Uses
Drofenine is a widely used anticholinergic drug. It acts on smooth muscle to stop muscle spasms.
Manufacturing Process
17.4 parts of diphenylacetic acid 2-(diethylamino)ethyl ester were solved in
200 parts of acetic acid and hydrogenated over platinum catalyst. After the
calculated volume of hydrogen was passed, the catalyst was filtered off and
the solvent was removed to dryness. Ether, water and a potassium carbonate
solution were added to the remaining oil and were thoroughly shaken. The
ether layer was washed with water and dried over potassium carbonate. The
solvent was removed, the remaining oil was distilled in vacuum to give 2-
(diethylamino)ethyl α-phenylcyclohexaneacetate; BP 150°-160°C/0.2 mm Hg.
In practice it is usually used as hydrochloride.
Therapeutic Function
Spasmolytic
DROFENINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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