ChemicalBook > CAS DataBase List > 2,6-Dichlorobenzoic acid

2,6-Dichlorobenzoic acid

Product Name
2,6-Dichlorobenzoic acid
CAS No.
50-30-6
Chemical Name
2,6-Dichlorobenzoic acid
Synonyms
AI3-33337;NSC 76599;CCRIS 8610;BRN 0973858;2,6-Dichlorobe;2,6-dichlorobenzoic;RARECHEM AL BO 0023;TIMTEC-BB SBB007694;2,6-dichlorobenzoate;2,6-Dichlorbenzoesure
CBNumber
CB1673902
Molecular Formula
C7H4Cl2O2
Formula Weight
191.01
MOL File
50-30-6.mol
More
Less

2,6-Dichlorobenzoic acid Property

Melting point:
139-142 °C (lit.)
Boiling point:
273.68°C (rough estimate)
Density 
1.4410 (rough estimate)
refractive index 
1.4590 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
14g/l
pka
1.69±0.10(Predicted)
form 
Fine Crystalline Powder
color 
White to beige
Water Solubility 
0.1-1 g/100 mL at 19 ºC
BRN 
973858
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
50-30-6(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 2,6-dichloro-(50-30-6)
EPA Substance Registry System
Benzoic acid, 2,6-dichloro- (50-30-6)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25-37/39
WGK Germany 
3
RTECS 
DG7000000
HazardClass 
IRRITANT
HS Code 
29163900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D57450
Product name
2,6-Dichlorobenzoic acid
Purity
98%
Packaging
25g
Price
$18.72
Updated
2024/03/01
TCI Chemical
Product number
D0339
Product name
2,6-Dichlorobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
D0339
Product name
2,6-Dichlorobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$40
Updated
2024/03/01
Alfa Aesar
Product number
A10542
Product name
2,6-Dichlorobenzoic acid, 98%
Packaging
25g
Price
$48.65
Updated
2024/03/01
Alfa Aesar
Product number
A10542
Product name
2,6-Dichlorobenzoic acid, 98%
Packaging
5g
Price
$17.4
Updated
2021/12/16
More
Less

2,6-Dichlorobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

2,6-Dichlorobenzoic Acid is an di-halogenated benzoic acid derivative and is used in the synthesis of Lux-S enzyme inhibitor.

Definition

ChEBI: 2,6-dichlorobenzoic acid is a chlorobenzoic acid carrying two chloro groups at positions 2 and 6 respectively. It has a role as a bacterial xenobiotic metabolite. It is a chlorobenzoic acid and a dichlorobenzene. It is functionally related to a benzoic acid. It is a conjugate acid of a 2,6-dichlorobenzoate.

Preparation

2,6-Dichlorobenzoic Acid can be prepared through several synthetic routes. One common method is the chlorination of benzoic acid in the presence of a catalyst such as phosphorus pentachloride or thionyl chloride. The reaction takes place under reflux in anhydrous conditions, resulting in the substitution of two chlorine atoms at positions 2 and 6 of the benzene ring. The resulting product is then isolated and purified through recrystallization from a suitable solvent. Another method involves the chlorination of the methyl ester of 2,6-dichlorobenzoic acid, followed by hydrolysis to yield the desired compound. Alternatively, it can also be synthesized through the oxidation of 2,6-dichlorotoluene using potassium permanganate or other oxidizing agents.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

2,6-Dichlorobenzoic acid is a halogenated carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in 2,6-Dichlorobenzoic acid to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.

Fire Hazard

Flash point data for 2,6-Dichlorobenzoic acid are not available; however, 2,6-Dichlorobenzoic acid is probably combustible.

Purification Methods

Crystallise the acid from EtOH and sublime it in vacuo.[Beilstein 9 IV 1005.] Aromatic acid impurities (to <0.05%) can be removed via the (±)--methylbenzylamine salt as described for 2,4-dichlorobenzoic acid [Ley & Yates Organic Process Research & Development 12 120 2008.]

2,6-Dichlorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2,6-Dichlorobenzoic acid Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
ecochem international chemical broker
Tel
--
Fax
--
Email
export@ecochem.dk
Country
Europe
ProdList
6371
Advantage
66
kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
More
Less

View Lastest Price from 2,6-Dichlorobenzoic acid manufacturers

Speranza Chemical Co., Ltd.
Product
2,6-Dichlorobenzoic acid 50-30-6
Price
US $35.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
20 tons
Release date
2019-12-24
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
2,6-Dichlorobenzoic acid 50-30-6
Price
US $40.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-30
airuikechemical co., ltd.
Product
2,6-dichlorobenzoic acid 50-30-6
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-03-29

50-30-6, 2,6-Dichlorobenzoic acidRelated Search:


  • 2,6-DICHLOROBENZOIC ACID
  • TIMTEC-BB SBB007694
  • RARECHEM AL BO 0023
  • 2,6-dichlorobenzoic
  • 2,6-dichloro-benzoicaci
  • 2,6-dichlorobenzoate
  • AI3-33337
  • BRN 0973858
  • CCRIS 8610
  • NSC 76599
  • Benzoicacid,2,6-dichloro-
  • TEPP PESTANAL (TETRAETHYL PYRO- PHOSPHAT
  • 2,6-Dichlorobenzoicacid,98%
  • 2,6-Dichlorobenzoic acid, 98+% 25GR
  • 2,6-DICLOROBENZOIC ACID
  • 2,6-Dichlorobenzoic Acid, 97+%
  • 2,6-Dichlorobe
  • 2,6-Dichlorobenzoic acid Benzoic acid, 2,6-dichloro- AI3-33337 BRN 0973858 CCRIS 8610 NSC 76599 2,6-dichlorobenzoate
  • 2,6-Dichlorobenzoic Acid &gt
  • 2,6-Dichlorbenzoesure
  • Lincomycin Impurity 1 Hydrochloride(Lincomycin EP Impurity D Hydrochloride)
  • C12402000 2,6-DichlorobenzoiCacid
  • 50-30-6
  • 50-30-0
  • C7H4O2Cl2
  • Organic Building Blocks
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acids
  • C7
  • C7
  • Carbonyl Compounds
  • Carboxylic Acids
  • Alpha sort
  • D
  • DAlphabetic
  • DIA - DIC
  • Pesticides&Metabolites
  • intermediate
  • FINE Chemical & INTERMEDIATES