ChemicalBook > CAS DataBase List > 1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride

1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride

Product Name
1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride
CAS No.
90604-02-7
Chemical Name
1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride
Synonyms
1-BENZHYDRYLAZETIDIN-3-OL HYDROCHLORIDE;1-(DiphenylMethyl)-3-hydroxyazetidine HCl;1-(diphenylmethyl)azetidin-3-ol hydrochloride;Baricitinib-008-HCl;Baricitinib Impurity 9 HCl;1-BENZHYDRYLAZETAN-3-OL-HCl;Baricitinib Impurity 13 HCl;N-BENZHYDRYLAZETIDIN-3-OL HCL;1-BENZHYDRYL AZETIDIN-3-OL HCL;1-benzhydrylazetidin-1-ium-3-ol
CBNumber
CB1683228
Molecular Formula
C16H18ClNO
Formula Weight
275.78
MOL File
90604-02-7.mol
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1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride Property

Melting point:
172-174°C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
color 
White to Pale Yellow
CAS DataBase Reference
90604-02-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37
Hazard Note 
Irritant
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D492848
Product name
1-(Diphenylmethyl)-3-hydroxyazetidineHydrochloride
Packaging
2.5g
Price
$45
Updated
2021/12/16
TRC
Product number
D492848
Product name
1-(Diphenylmethyl)-3-hydroxyazetidineHydrochloride
Packaging
5g
Price
$60
Updated
2021/12/16
Synthonix
Product number
B10215
Product name
1-Benzhydrylazetidin-3-olhydrochloride
Purity
97.0%
Packaging
500g
Price
$60
Updated
2021/12/16
Ark Pharm
Product number
AK-27694
Product name
1-Benzhydrylazetidin-3-olhydrochloride
Purity
97%
Packaging
10g
Price
$7
Updated
2021/12/16
Matrix Scientific
Product number
112093
Product name
3-Azetidinol
Purity
1-(diphenylmethyl)-hydrochloride (1:1)
Packaging
1g
Price
$11
Updated
2021/12/16
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1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride Chemical Properties,Usage,Production

Uses

1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride is a vital compound and can be used to synthesise 1-Benzhydrylazetidin-3-one and 1-benzhydrylazetidin-3-ol.

Synthesis

18621-17-5

90604-02-7

General procedure for the synthesis of 1-(diphenylmethyl)-3-hydroxyazetidine hydrochloride from 1-diphenylmethyl-3-hydroxyazetidine: 1-(diphenylmethyl)-3-hydroxyazetidine (9.70 g) was suspended in a 4.5 M hydrochloric acid solution of ethyl acetate (35 mL) at room temperature and the reaction was stirred for 10 minutes. Subsequently, the solvent was removed by evaporation to give 1-(diphenylmethyl)-3-hydroxyazetidine hydrochloride (12.0 g, 100% yield). The product was characterized by 1H-NMR (300 MHz, DMSO-d6, with TMS as internal standard) with the following chemical shifts (ppm): δ 7.30-7.70 (10H, m, arylhydrogen), 5.85 (1H, s, CH), 5.80 (1H, d, OH), 4.46 (1H, m, CH), 3.70-4.20 (4H, m, CH2 ).

References

[1] Patent: WO2007/118830, 2007, A1. Location in patent: Page/Page column 91

1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride 90604-02-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-11-28
Henan Aochuang Chemical Co.,Ltd.
Product
1-(DIPHENYLMETHYL)-3-HYDROXYAZETIDINE HYDROCHLORIDE 90604-02-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-19
Career Henan Chemical Co
Product
1-(DIPHENYLMETHYL)-3-HYDROXYAZETIDINE HYDROCHLORIDE 90604-02-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-03-05

90604-02-7, 1-(Diphenylmethyl)-3-Hydroxyazetidine HydrochlorideRelated Search:

3-Hydroxyazetidine hydrochloride 3-AZETIDINOL 1-(Diphenylmethyl)-3-hydroxyazetidine Azetidine hydrochloride

  • N-BENZHYDRYLAZETIDIN-3-OL HCL
  • 1-BENZHYDRYL AZETIDIN-3-OL HCL
  • 1-BENZHYDRYLAZETIDIN-3-OL HYDROCHLORIDE
  • 1-(DIPHENYLMETHYL)-3-HYDROXYAZETIDINE HYDROCHLORIDE
  • 1-(Diphenylmethyl)-3-azetidinolhydrochloride
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  • 1-(Diphenylmethyl)-3-hydroxyazetidine hydrochloride 95%
  • N-Benzhydrylazetidin-3-ol hydrochloride
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  • 1-(diphenylmethyl)azetidin-3-ol hydrochloride
  • 1-benzhydryl azetindin-3-ol hydrochloride
  • 3-azetidinol, 1-(diphenylmethyl)-
  • 1-BENZHYDRYLAZETAN-3-OL-HCl
  • 1-(DiphenylMethyl)-3-hydroxyazetidine HCl
  • 3-Azetidinol, 1-(diphenylMethyl)-, hydrochloride (1:1)
  • 1- twobenzeneMethyl -3- hydroxyazetidinehydrochloride
  • 1-(Diphenylmethyl)-3-hydroxyazetidine hydrochloride 1-Benzhydrylazetidin-3-ol hydrochloride
  • 1-benzhydryl-3-azetidin-1-iumol chloride
  • 1-benzhydrylazetidin-1-ium-3-ol chloride
  • 1-Benzhydryl-3-zaetidinol hydrochloride
  • Baricitinib-008-HCl
  • 1-benzhydrylazetidin-1-ium-3-ol
  • -(DIPHENYLMETHYL)-3-HYDROXYAZETIDINE HYDROCHLORIDE
  • 1-(diphenylmethyl)-3-Azetidinol hydrochloride (1:1)
  • N-Diphenylmethyl-3-hydroxyazetidine hydrochloride
  • Baricitinib Impurity 13 HCl
  • Baricitinib Impurity 9 HCl
  • 1-Benzhydryl-3-azetidinol hydrochloride
  • 90604-02-7
  • C16H18NOCl
  • C16H17NOHCl
  • C16H17NOClH