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N,N'-Diacetylchitobiose

Product Name
N,N'-Diacetylchitobiose
CAS No.
35061-50-8
Chemical Name
N,N'-Diacetylchitobiose
Synonyms
CHITOBIOSE;N-acetylated Chitobiose;diNAG;C01674;Chitinbiose;CHITOBIOSE(RG);GlcNAcb1, 4GlcNAc;N-((2R,3R,4R,5S,6R);-Diacetylchitobiose;-Diacetyl chitobiose
CBNumber
CB1689710
Molecular Formula
C16H28N2O11
Formula Weight
424.4
MOL File
35061-50-8.mol
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N,N'-Diacetylchitobiose Property

Melting point:
245-247 °C(lit.)
Boiling point:
927.7±65.0 °C(Predicted)
alpha 
18.5 - 39.5 º (c=1% in H2O)
Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: 50 mg/mL, clear, colorless
pka
12.85±0.20(Predicted)
form 
Solid
color 
White to Pale Yellow
optical activity
+32.3 → +16.0
BRN 
61689
Stability:
Hygroscopic
InChIKey
CDOJPCSDOXYJJF-CBTAGEKQSA-N
LogP
-1.870 (est)
CAS DataBase Reference
35061-50-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26-36
WGK Germany 
3
F 
10
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D1523
Product name
N,N′-Diacetylchitobiose
Purity
≥96% (HPLC)
Packaging
10mg
Price
$369
Updated
2024/03/01
TCI Chemical
Product number
D4215
Product name
N,N'-Diacetylchitobiose
Purity
>98.0%(HPLC)
Packaging
20mg
Price
$357
Updated
2024/03/01
TRC
Product number
D310500
Product name
N,N''-Diacetylchitobiose
Packaging
10mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
OD00769
Product name
N,N'-Diacetylchitobiose
Packaging
25mg
Price
$120
Updated
2021/12/16
Biosynth Carbosynth
Product number
OD00769
Product name
N,N'-Diacetylchitobiose
Packaging
50mg
Price
$195
Updated
2021/12/16
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N,N'-Diacetylchitobiose Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

An inhibitor of lysozyme, reverses myocardial depression and lessens norepinephrine requirements in Escherichia coli sepsis in dogs.

Uses

lectin inhibitor, immunopotentiator

Uses

Diacetylchitobiose/Chitobiose, a dimer of β(1,4) linked N-acetyl-D glucosamine, is used as an alternative source of N-acetylglucosamine by some bacteria. It is used in fermentation research to study, differentiate and characterize chitobiose transporter systems and enzymes such as β-N-acetylglucosaminidase(s) and chitobiose phosphorylase(s).

Definition

ChEBI: N,N'-diacetylchitobiose is the N,N'-diacetylated derivative of chitobiose, but with no stereodesignation for the anomeric carbon atom. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a beta-D-glucosaminyl-(1->4)-D-glucosamine.

Biochem/physiol Actions

In chitinolytic bacteria, such as Vibrio, Streptomyces and Serratia, N,N′-Diacetylchitobiose (GlcNAc2) is not only a major breakdown product of chitinase, but it is also the smallest substance that induces chitinase production. It can also be utilized as a carbon source by E. coli, which does not express chitinases, but is exposed to GlcNAc2 produced by intestinal chitinolytic bacteria. In most organisms, the uptake of GlcNAc2 occurs via the phosphoenolpyruvate:glycose phosphotransferase system (PTS). GlcNAc2 has also been used as a substrate or inhibitor to study the activity of glycolytic enzymes.

Purification Methods

Recrystallise N,N'-Diacetylchitobiose from aqueous MeOH or aqueous EtOH/1,2-dimethoxyethane. [Zilliken et al. J Chem Soc 77 1296 1955, Beilstein 18/11 V 147.]

N,N'-Diacetylchitobiose Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N'-Diacetylchitobiose Suppliers

Americas 1 Canada 1 China 92 Europe 1 France 1 Germany 3 India 1 Japan 2 Sweden 1 Switzerland 3 United Kingdom 6 United States 16 Global 128
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from N,N'-Diacetylchitobiose manufacturers

Henan Fengda Chemical Co., Ltd
Product
N,N'-Diacetylchitobiose 35061-50-8
Price
US $8.00-3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-03
Henan Aochuang Chemical Co.,Ltd.
Product
N,N'-Diacetylchitobiose 35061-50-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-19
Career Henan Chemical Co
Product
N,N'-Diacetylchitobiose 35061-50-8
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-24

35061-50-8, N,N'-DiacetylchitobioseRelated Search:

N,N',N''-TRIACETYLCHITOTRIOSE N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose N,N'-Diacetylchitobiose 2-Deoxy-D-glucose N-Acetyl-D-Glucosamine Methyl 2-Acetamido-4-O-(2-acetamido-2-deoxy-b-D-gluco- pyranosyl)-2-deoxy-6-O-(a-L-fucopyranosyl)-b-D-glucopyranoside P-NITROPHENYL BETA-D-N,N'-DIACETYLCHITOBIOSE 4-METHYLUMBELLIFERYL-N,N',N''-TRIACETYL-BETA-CHITOTRIOSIDE 4-METHYLUMBELLIFERYL BETA-D-N,N',N',N''-TETRAACETYLCHITOTETRAOSIDE N',N'',N''',N''''-Pentaacetylchitopentaose D-ALPHA-CHITOBIOSE OCTAACETATE GMDP P-NITROPHENYL BETA-D-N,N',N''-TRIACETYLCHITOTRIOSE BENZYL N,N'-DIACETYL-B-CHITOBIOSIDE 4-METHYLUMBELLIFERYL BETA-D-N,N'-DIACETYL-CHITOBIOSIDE Methyl 2-Acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-b- D-glucopyranosyl)-2-deoxy-b-D-glucopyranoside N',N'',N'''-Tetraacetylchitotetraose 8-ETHOXYCARBONYLOCTYL N,N'-DIACETYL-BETA-CHITOBIOSIDE

  • N-((3R,5S,6R)-5-(((2S,3R,5S,6R)
  • N-acetylated Chitobiose
  • Di-N-acetyl-D-chitobiose
  • -Diacetyl chitobiose
  • D-Glucose, 2-(acetylamino)-4-O-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl-2-deoxy-
  • 2-acetamido-2-deoxy-4-o-(2-acetamido-2-deoxy-β-d-gluco-pyranosyl)-d-glucopyranose
  • CHITOBIOSE(RG)
  • 2-(Acetylamino)-4-O-[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]-2-deoxy-D-glucose
  • Bis(N-acetyl)chitobiose
  • Chitobiose Diacetate
  • N,N'-Diacetyl-D-chitobiose
  • 2-(Acetylamino)-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-deoxy-D-glucose
  • Di-N-acetyl-D-glucosamine
  • diNAG
  • N,N'-Diacetylglucosamine
  • 4-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-2-acetamido-2-deoxy-D-glucose
  • C01674
  • N,N′-Diacetylchitobiose,2-Acetamido-2-deoxy-4-O-(2-acetamido-2-deoxy-β-D-gluco-pyranosyl)-D-glucopyranose, 4-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-2-acetamido-2-deoxy-D-glucose, Chitobiose
  • Chitobiose, N,N-Diacetyl-
  • N,N'-DIACETYLCHITOBIOSE
  • 2-ACETAMIDO-2-DEOXY-4-O-[2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSYL]-D-GLUCOPYRANOSE
  • 2-ACETAMIDO-2-DEOXY-4-O-(2-ACETAMIDO-2-DEOXY-BETA-D-GLUCO-PYRANOXYL)-D-GLUCOPYRANOSE
  • 4-O-(2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSYL)-2-ACETAMIDO-2-DEOXY-D-GLUCOSE
  • N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-aldehydo-D-glucosamine
  • -2,4-dihydroxy-6-(hydroxymethyl)
  • -3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)
  • N-((2R,3R,4R,5S,6R)
  • GLCNAC-BETA1-4GLCNAC
  • DI-(N-ACETYL) CHITOBIOSE
  • CHITOBIOSE, DI-N-ACETYL
  • CHITOBIOSE
  • Diacetyl-Chiotobiose - 30mg
  • N,N'-Diacetylchitobiose&gt
  • Chitin oligosaccharides DP2 /chitinbiose
  • D-Glucose, 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-deoxy-
  • Chitinbiose
  • N,N'-Diacetylchitobiose USP/EP/BP
  • Glucosamine Hydrochloride Impurity 12
  • -Diacetylchitobiose
  • N,N'-Diacetylchitobiose 35061-50-8
  • Glucosamine Sulfate Impurity 5
  • N[2H3-methyl],N’[2H3-methyl]-diacetylchitobiose
  • GlcNAcb1, 4GlcNAc
  • N,N'-Diacetyl chitobiose
  • N-[(2R,3R,4S,5R)-4-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,5,6-trihydroxy-1-oxohexan-2-yl]acetamide
  • Glucosamine sulphate Impurity 7
  • 35061-50-8
  • C16H28N2O11
  • C16H28O11N2
  • Disaccharide
  • Carbohydrates
  • Biochemicals and Reagents
  • BioChemical
  • Oligosaccharides