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Methyl isonicotinate

Product Name
Methyl isonicotinate
CAS No.
2459-09-8
Chemical Name
Methyl isonicotinate
Synonyms
4-Carbomethoxypyridine;NSC 18257;Methyl isonicotite;RARECHEM AL BF 0097;methyl isonicoitate;METHYL ISONICOTINATE;MethylIsonicotinate>Topiroxostat impurity D;Isonicotinic acid methyl;Methyl isonicotinate 98%
CBNumber
CB1693690
Molecular Formula
C7H7NO2
Formula Weight
137.14
MOL File
2459-09-8.mol
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Methyl isonicotinate Property

Melting point:
8-8.5 °C (lit.)
Boiling point:
207-209 °C (lit.)
Density 
1.161 g/mL at 25 °C (lit.)
vapor pressure 
32.2Pa at 25℃
refractive index 
n20/D 1.512(lit.)
Flash point:
180 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Ethyl Acetate
pka
pK1:3.26(+1) (25°C)
form 
Liquid
color 
Clear orange to brown
Specific Gravity
1.001
Water Solubility 
Slightly soluble in water.
BRN 
114618
LogP
0.464 at 25℃
CAS DataBase Reference
2459-09-8(CAS DataBase Reference)
NIST Chemistry Reference
Pyridine-4-carboxylic acid, methyl ester(2459-09-8)
EPA Substance Registry System
4-Pyridinecarboxylic acid, methyl ester (2459-09-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
10
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
CBL
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M52950
Product name
Methyl isonicotinate
Purity
98%
Packaging
100g
Price
$69.66
Updated
2025/07/31
TCI Chemical
Product number
I0141
Product name
Methyl Isonicotinate
Purity
>99.0%(T)
Packaging
25g
Price
$29
Updated
2025/07/31
TCI Chemical
Product number
I0141
Product name
Methyl Isonicotinate
Purity
>99.0%(T)
Packaging
100g
Price
$87
Updated
2025/07/31
TRC
Product number
M323340
Product name
Methyl isonicotinate
Packaging
10g
Price
$145
Updated
2021/12/16
AK Scientific
Product number
J91903
Product name
Methyl isonicotinate
Packaging
5g
Price
$10
Updated
2021/12/16
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Methyl isonicotinate Chemical Properties,Usage,Production

Chemical Properties

CLEAR ORANGE TO BROWN LIQUID

Uses

Methyl Isonicotinate induces increased walking and take-off behavior in western flower thrips, Frankliniella occidentalis.

Uses

Methyl isonicotinate can be used in:

  • The preparation of various photosensitizers for applications in dye-sensitized solar cells (DSSCs).
  • Synthesizing luminophore for luminescent metal-organic framework (MOF).
  • Nonaqueous redox flow batteries as pyridine-based anolyte material that undergoes two reversible reductions in solutions with Li-ion electrolytes.

Uses

Methyl Isonicotinate induces increased walking and take-off behaviour in western flower thrips, Frankliniella occidentalis.

Flammability and Explosibility

Not classified

Synthesis

872-85-5

67-56-1

2459-09-8

GENERAL STEPS: A mixture of chlorobrominated resin and K2CO3 in MeOH-H2O (8:2, 3 mL) was placed in a round-bottomed flask equipped with a magnetic stirrer. 4-Pyridinecarboxaldehyde (1 mmol, 1 equiv.) was added to it slowly and the reaction mixture was stirred at room temperature. The progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was filtered and the filtrate was extracted with ether (Et2O). The ether layer was washed sequentially with water, brine, dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated. If necessary, the residue was purified by column chromatography on silica gel (60-120 mesh) using a mixture of petroleum ether (PE) and ethyl acetate (EtOAc) (9:1) as eluent.

References

[1] Synthesis, 2010, # 2, p. 276 - 282
[2] Synlett, 2016, vol. 27, # 9, p. 1344 - 1348
[3] Tetrahedron Letters, 2014, vol. 55, # 39, p. 5358 - 5360
[4] Synthetic Communications, 2010, vol. 40, # 2, p. 186 - 195
[5] Synthesis, 2009, # 9, p. 1578 - 1581

Methyl isonicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl isonicotinate Suppliers

Apollo Scientific Ltd.
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sales@apolloscientific.co.uk
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United Kingdom
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Leancare Ltd.
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enquiry@leancare.co.uk
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United Kingdom
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MOLEKULA Ltd.
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kevinbanks@molekula.com
Country
United Kingdom
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CARBONE SCIENTIFIC CO.,LTD
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sales@carbonesci.com
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United Kingdom
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Eurolabs Limited
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United Kingdom
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View Lastest Price from Methyl isonicotinate manufacturers

Shandong Vital Biotechnology Co., Ltd.
Product
Methyl isonicotinate 2459-09-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100tons
Release date
2025-11-19
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Methyl isonicotinate 2459-09-8
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
300/month
Release date
2021-06-03
Shaanxi Xianhe Biotech Co., Ltd
Product
Methyl isonicotinate 2459-09-8
Price
US $0.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
1000KG
Release date
2025-04-18

2459-09-8, Methyl isonicotinateRelated Search:


  • METHYL 4-PYRIDINECARBOXYLATE
  • METHYL ISONICOTINATE
  • METHYL PYRIDINE-4-CARBOXYLATE
  • ISONICOTINIC ACID METHYL ESTER
  • PYRIDINE-4-CARBOXYLIC ACID METHYL ESTER
  • RARECHEM AL BF 0097
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  • 4-Methoxycarbonylpyridine
  • 4-Pyridinecarboxylic acid, methyl ester
  • 4-pyridinecarboxylicacid,methylester
  • 4-pyridinecarboxylicacidmethylester
  • Methyl Isonicotinate 4-Picolinic Acid Methyl Ester Methyl 4-Pyridine Carbonate
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  • Isonicotinic acid methyl
  • methyl pyridine-4-carboxylate cas 2459-09-8
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  • NSC 18257
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  • Methyl Isonicotinate , 99.0%(T)
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