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2-Hydroxy-2-methylbutyric acid

Product Name
2-Hydroxy-2-methylbutyric acid
CAS No.
3739-30-8
Chemical Name
2-Hydroxy-2-methylbutyric acid
Synonyms
DK764;2-Hydroxy-2-methylbu;2-hydroxy-2-methyl-butanoicaci;2-HYDROXY-2-METHYLBUTYRIC ACID;2-Methyl-2-hydroxybutanoic acid;2-Ethyl-2-hydroxypropionic acid;2-HYDROXY-2-METHYLBUTANOIC ACID;2-Hydroxy-2-methylbutyricAcid>2-HYDROXY-2-METHYL-N-BUTYRIC ACID;Butanoic acid, 2-hydroxy-2-methyl-
CBNumber
CB1706512
Molecular Formula
C5H10O3
Formula Weight
118.13
MOL File
3739-30-8.mol
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2-Hydroxy-2-methylbutyric acid Property

Melting point:
73-75 °C (lit.)
Boiling point:
109 °C / 9mmHg
Density 
1.144±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in DMSO
form 
powder to crystal
pka
pK1:3.991 (18°C)
color 
White to Almost white
Water Solubility 
within almost transparency
InChI
1S/C5H10O3/c1-3-5(2,8)4(6)7/h8H,3H2,1-2H3,(H,6,7)
InChIKey
MBIQENSCDNJOIY-UHFFFAOYSA-N
SMILES
CCC(C)(O)C(O)=O
CAS DataBase Reference
3739-30-8(CAS DataBase Reference)
NIST Chemistry Reference
2-Hydroxy-2-methylbutyric acid(3739-30-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HS Code 
2918199890
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H40009
Product name
2-Hydroxy-2-methylbutyric acid
Purity
98%
Packaging
5g
Price
$98.4
Updated
2024/03/01
TCI Chemical
Product number
H0636
Product name
2-Hydroxy-2-methylbutyric Acid
Purity
>98.0%(T)
Packaging
5g
Price
$57
Updated
2025/07/31
TCI Chemical
Product number
H0636
Product name
2-Hydroxy-2-methylbutyric Acid
Purity
>98.0%(T)
Packaging
25g
Price
$176
Updated
2025/07/31
TRC
Product number
H973060
Product name
2-Hydroxy-2-methylbutyric acid
Packaging
5g
Price
$50
Updated
2021/12/16
AK Scientific
Product number
J55166
Product name
2-Hydroxy-2-methylbutyric acid
Packaging
1g
Price
$15
Updated
2021/12/16
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2-Hydroxy-2-methylbutyric acid Chemical Properties,Usage,Production

Uses

2-Hydroxy-2-methylbutyric acid can be used as:

  • A complexing agent in a new electrolytic system, applicable in the isotachophoretic lanthanide separation.
  • An aldehyde surrogate to prepare pyrrolo[1,2-a]quinoxaline derivatives by reacting with 2-(1H-pyrrol-1-yl)aniline.
  • A starting material to synthesize Cr(V) reagent named sodium bis(2-hydroxy-2-methylbutyrato)oxochromate(V) (Aldrich cat. no. ALD00006) applicable in the total synthesis of (?)-taxuyunnanine D.

Definition

ChEBI: A branched-chain fatty acid that is 2-methylbutyric acid substituted at C-2 by a hydroxy group.

IC 50

Human Endogenous Metabolite

Purification Methods

Crystallise the acid from *benzene, and sublime it at 90o. [Beilstein 3 H 324.] IRRITANT.

2-Hydroxy-2-methylbutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Hydroxy-2-methylbutyric acid Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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4006356688 18621169109
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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021-67121385
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Sales-CN@TCIchemicals.com
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Energy Chemical
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Shandong Xiya Chemical Co., Ltd
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Syntechem Co.,Ltd
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0571-82693216
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+86-571-82880190
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View Lastest Price from 2-Hydroxy-2-methylbutyric acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Hydroxy-2-methylbutyric acid 3739-30-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20t
Release date
2024-07-14
Dideu Industries Group Limited
Product
2-Hydroxy-2-methylbutyric acid 3739-30-8
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-17
Career Henan Chemical Co
Product
2-HYDROXY-3-METHYLBUTYRIC ACID 3739-30-8
Price
US $20.00/KG
Min. Order
10KG
Purity
98%
Supply Ability
100kg
Release date
2018-08-02

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