N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE

Product Name: N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
CAS No.: 70967-90-7
Chemical Name: N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
Synonyms: M4765;MeOSuc-AAPV-pNA;MEOSUC-ALA-ALA-PRO-VAL-PNA;LEUKOCYTE ESTERASE SUBSTRATE;ELASTASE SUBSTRATE I, COLORIMETRIC;MeOSuc-AAPV-pNA, Chromogenic Substrate;MEO-SUC-ALA-ALA-PRO-VAL-PARANITROANILIDE;METHOXYSUCCINYL-ALA-ALA-PRO-VAL-P-NITROANILIDE;N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE;N-(Methoxysuccinyl)-Ala-Ala-Pro-Val 4-nitroanilide
CBNumber: CB1725814
Molecular Formula: C27H38N6O9
Formula Weight: 590.63
MOL File: 70967-90-7.mol

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N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE Property

Melting point:: 203-205°C
Boiling point:: 958.4±65.0 °C(Predicted)
Density: 1.297±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: 25 mg/mL, clear, light yellow
form: Off-white solid
pka: 13.29±0.20(Predicted)
color: White to Off-White
BRN: 6266359

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10-21

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 454454
Product name: N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide
Purity: Soluble, specific substrate for human leukocyte elastase.
Packaging: 50mg
Price: $155
Updated: 2024/03/01

Sigma-Aldrich

Product number: 324696
Product name: Elastase Substrate I, Colorimetric
Purity: A specific chromogenic substrate for human neutrophil elastase.
Packaging: 10mg
Price: $82.8
Updated: 2024/03/01

Cayman Chemical

Product number: 17601
Product name: MeOSuc-AAPV-pNA
Purity: ≥98%
Packaging: 5mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 17601
Product name: MeOSuc-AAPV-pNA
Purity: ≥98%
Packaging: 10mg
Price: $57
Updated: 2024/03/01

Sigma-Aldrich

Product number: M4765
Product name: N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide
Purity: elastase substrate
Packaging: 10mg
Price: $103
Updated: 2024/03/01

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N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE Chemical Properties,Usage,Production

Description

Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.

Uses

N-Methoxysuccinyl-Ala-Ala-Pro-Val p-Nitroanilide is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3 but not cathespin.

N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE Suppliers

China 76 Germany 1 Japan 1 Switzerland 1 United Kingdom 2 United States 12 Global 93

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
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Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18217
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
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Chemsky (shanghai) International Co.,Ltd

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Email: shchemsky@sina.com
Country: China
ProdList: 15421
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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Shanghai Macklin Biochemical Co.,Ltd.

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Fax: 021-50706099
Email: shenlinxing@macklin.cn
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Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
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parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9604
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Shanghai Chaolan Chemical Technology Center

Tel: QQ:65489617 15618227136
Fax: 21-5161 9052
Email: info@SuperLan-chem.com
Country: China
ProdList: 9445
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View Lastest Price from N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE manufacturers

Career Henan Chemical Co

Product: N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE 70967-90-7
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-18

70967-90-7, N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDERelated Search:

Elastase Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide, Methanol AC-ALA-ALA-ALA-PNA AC-ALA-ALA-PRO-ALA-PNA AC-ALA-ALA-PRO-VAL-PNA MEOSUC-LYS(2-PICOLINOYL)-ALA-PRO-VAL-PNA SUC-ALA-ALA-PRO-VAL-PNA H-VAL-PNA AC-ALA-PRO-ALA-PNA N-(4-AMINOPHENYL)-3-METHYLBUTANAMIDE N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE SUC-ALA-ALA-PRO-ALA-PNA

N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE

N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE 4-NITROANILIDE

ELASTASE SUBSTRATE I, COLORIMETRIC

MEO-SUC-ALA-ALA-PRO-VAL-PARANITROANILIDE

MEOSUC-ALA-ALA-PRO-VAL-PNA

METHOXYSUCCINYL-ALA-ALA-PRO-VAL-P-NITROANILIDE

METHOXYSUCCINYL-ALA-ALA-PRO-VAL-P-NITROANILIDE, METHANOL ADDUCT

L-Valinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-

N-methoxysuccinyl-alanyl-alanyl-prolyl-valine-4-nitroanilide

N(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine NA

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val 4-nitroanilide, N-(Methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine 4-nitroanilide

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val 4-nitroanilide

MeOSuc-AAPV-pNA, Chromogenic Substrate

MeOSuc-AAPV-pNA

M4765

N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE, BIOCHEMIKA

LEUKOCYTE ESTERASE SUBSTRATE

Elastase Substrate I, Colorimetric - CAS 70967-90-7 - Calbiochem

Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide - CAS 70967-90-7 - Calbiochem

methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-3-methyl-1-(4-nitroanilino)-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate

N-(4-Methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide

70967-90-7

C27H38N6O9

BioChemical

Biochemicals and Reagents

Substrates by Enzyme

Enzyme Substrates

Enzymes, Inhibitors, and Substrates

Elastase, leukocyte