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N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE

Product Name
N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
CAS No.
70967-90-7
Chemical Name
N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
Synonyms
M4765;MeOSuc-AAPV-pNA;MEOSUC-ALA-ALA-PRO-VAL-PNA;LEUKOCYTE ESTERASE SUBSTRATE;ELASTASE SUBSTRATE I, COLORIMETRIC;MeOSuc-AAPV-pNA, Chromogenic Substrate;MEO-SUC-ALA-ALA-PRO-VAL-PARANITROANILIDE;METHOXYSUCCINYL-ALA-ALA-PRO-VAL-P-NITROANILIDE;N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE;N-(Methoxysuccinyl)-Ala-Ala-Pro-Val 4-nitroanilide
CBNumber
CB1725814
Molecular Formula
C27H38N6O9
Formula Weight
590.63
MOL File
70967-90-7.mol
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N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE Property

Melting point:
203-205°C
Boiling point:
958.4±65.0 °C(Predicted)
Density 
1.297±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMF: 25 mg/mL, clear, light yellow
form 
Off-white solid
pka
13.29±0.20(Predicted)
color 
White to Off-White
BRN 
6266359
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
454454
Product name
N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide
Purity
Soluble, specific substrate for human leukocyte elastase.
Packaging
50mg
Price
$155
Updated
2024/03/01
Sigma-Aldrich
Product number
324696
Product name
Elastase Substrate I, Colorimetric
Purity
A specific chromogenic substrate for human neutrophil elastase.
Packaging
10mg
Price
$82.8
Updated
2024/03/01
Cayman Chemical
Product number
17601
Product name
MeOSuc-AAPV-pNA
Purity
≥98%
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
17601
Product name
MeOSuc-AAPV-pNA
Purity
≥98%
Packaging
10mg
Price
$57
Updated
2024/03/01
Sigma-Aldrich
Product number
M4765
Product name
N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide
Purity
elastase substrate
Packaging
10mg
Price
$103
Updated
2024/03/01
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N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE Chemical Properties,Usage,Production

Description

Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.

Uses

N-Methoxysuccinyl-Ala-Ala-Pro-Val p-Nitroanilide is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3 but not cathespin.

N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE Suppliers

Biomol Feinchemikalien GmbH
Tel
--
Fax
--
Email
info@biomol.de
Country
Germany
ProdList
479
Advantage
74
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View Lastest Price from N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE manufacturers

Career Henan Chemical Co
Product
N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE 70967-90-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-18

70967-90-7, N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDERelated Search:


  • N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE
  • N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE 4-NITROANILIDE
  • ELASTASE SUBSTRATE I, COLORIMETRIC
  • MEO-SUC-ALA-ALA-PRO-VAL-PARANITROANILIDE
  • MEOSUC-ALA-ALA-PRO-VAL-PNA
  • METHOXYSUCCINYL-ALA-ALA-PRO-VAL-P-NITROANILIDE
  • METHOXYSUCCINYL-ALA-ALA-PRO-VAL-P-NITROANILIDE, METHANOL ADDUCT
  • L-Valinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-
  • N-methoxysuccinyl-alanyl-alanyl-prolyl-valine-4-nitroanilide
  • N(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine NA
  • N-(Methoxysuccinyl)-Ala-Ala-Pro-Val 4-nitroanilide, N-(Methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine 4-nitroanilide
  • N-(Methoxysuccinyl)-Ala-Ala-Pro-Val 4-nitroanilide
  • MeOSuc-AAPV-pNA, Chromogenic Substrate
  • MeOSuc-AAPV-pNA
  • M4765
  • N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL P-NITROANILIDE, BIOCHEMIKA
  • LEUKOCYTE ESTERASE SUBSTRATE
  • Elastase Substrate I, Colorimetric - CAS 70967-90-7 - Calbiochem
  • Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide - CAS 70967-90-7 - Calbiochem
  • methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-3-methyl-1-(4-nitroanilino)-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate
  • N-(4-Methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide
  • 70967-90-7
  • C27H38N6O9
  • BioChemical
  • Biochemicals and Reagents
  • Substrates by Enzyme
  • Enzyme Substrates
  • Enzymes, Inhibitors, and Substrates
  • Elastase, leukocyte