N-acetyl aspartyl-glutaMic acid
- Product Name
- N-acetyl aspartyl-glutaMic acid
- CAS No.
- 3106-85-2
- Chemical Name
- N-acetyl aspartyl-glutaMic acid
- Synonyms
- NAAG;NAAGA;Naaxia;α-NAAG;ZY-15106;AC-ASP-GLU;ALPHA-NAAG;ACETYL-D-E;AC-ASP-GLU-OH;AC-ASP-GLU H2O
- CBNumber
- CB1742046
- Molecular Formula
- C11H16N2O8
- Formula Weight
- 304.25
- MOL File
- 3106-85-2.mol
N-acetyl aspartyl-glutaMic acid Property
- Melting point:
- 171-173 °C
- Boiling point:
- 769.5±60.0 °C(Predicted)
- Density
- 1.472±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O: 50 mg/mL
- form
- powder
- pka
- 3.04±0.10(Predicted)
- color
- white
- optical activity
- [α]22/D 34.5°, c = 1.1 in H2O(lit.)
- Water Solubility
- Soluble to 100 mM in water
- Stability:
- Hygroscopic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A5930
- Product name
- N-Acetyl-Asp-Glu
- Purity
- ≥97% (TLC), powder
- Packaging
- 25mg
- Price
- $137
- Updated
- 2024/03/01
- Product number
- A5930
- Product name
- N-Acetyl-Asp-Glu
- Purity
- ≥97% (TLC), powder
- Packaging
- 100mg
- Price
- $384
- Updated
- 2024/03/01
- Product number
- 166584
- Product name
- Spaglumic Acid
- Packaging
- 50mg
- Price
- $403
- Updated
- 2021/12/16
- Product number
- S679100
- Product name
- SpaglumicAcid
- Packaging
- 50mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FA05316
- Product name
- N-Acetyl-L-aspartyl-L-glutamic acid
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
N-acetyl aspartyl-glutaMic acid Chemical Properties,Usage,Production
Chemical Properties
White powder
Uses
N-Acetyl-Asp-Glu has been used in N-acetylated α-linked acidic dipeptidase (NAALADase) assay and affinity experiments.
Uses
N-acetyl aspartyl-glutamic acid is a spaglumic acid is a marker of neuronal integrity and was used in the detection of therapeutic values of antidrepressant treatments.
Definition
ChEBI: A dipeptide composed of N-acetyl-L-aspartic acid and L-glutamic acid joined by a peptide linkage.
General Description
NAAG is a neuropeptide and a neurotransmitter that is abundant in the mammalian nervous system. It remains uncertain whether this compound activates NMDA receptors; however, it is clearly demonstrated to act as a selective agonist of mGluR3, both in vitro and in vivo.
Biochem/physiol Actions
Endogenous neurotransmitter localized to neurons with high affinity for metabotropic glutamate receptors, mGluR3. It is an antagonist at NMDA receptors. Catabolized by carboxypeptidase II, which is expressed on astrocyte membranes, to N-acetylaspartate and glutamate.
storage
-20°C