ChemicalBook > CAS DataBase List > beta-Amyrin

beta-Amyrin

Product Name
beta-Amyrin
CAS No.
559-70-6
Chemical Name
beta-Amyrin
Synonyms
B-AMYRIN;β-Amyrin;β-Amyrine;AMYRIN, B-;b-Amyrenol;Nsc 527971;beta-aMyin;BETA-AMYRIN;β-Amyrin-RM;beta-Amyrenol
CBNumber
CB1749883
Molecular Formula
C30H50O
Formula Weight
426.73
MOL File
559-70-6.mol
More
Less

beta-Amyrin Property

Melting point:
187-190°C
alpha 
D19 +99.8° (c = 1.3 in benzene)
Boiling point:
bp0.8 260°
Density 
0.9600 (rough estimate)
refractive index 
1.4910 (estimate)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
15.18±0.70(Predicted)
color 
White to Off-White
optical activity
+9120 (c 1.23, CHCl3)
BRN 
2063468
InChIKey
JFSHUTJDVKUMTJ-QHPUVITPSA-N
LogP
10.481 (est)
CAS DataBase Reference
559-70-6(CAS DataBase Reference)
NIST Chemistry Reference
«BETA»-amyrin(559-70-6)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
22
Safety Statements 
22-45
WGK Germany 
3
10-23
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL80292
Product name
β-Amyrin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$332
Updated
2025/07/31
Sigma-Aldrich
Product number
09236
Product name
β-Amyrin
Purity
analytical standard
Packaging
10mg
Price
$755
Updated
2025/07/31
Cayman Chemical
Product number
20949
Product name
β-Amyrin
Purity
≥95%
Packaging
1mg
Price
$87
Updated
2024/03/01
Cayman Chemical
Product number
20949
Product name
β-Amyrin
Purity
≥95%
Packaging
5mg
Price
$357
Updated
2024/03/01
Cayman Chemical
Product number
20949
Product name
β-Amyrin
Purity
≥95%
Packaging
10mg
Price
$595
Updated
2024/03/01
More
Less

beta-Amyrin Chemical Properties,Usage,Production

Uses

nociceptive

Definition

ChEBI: A pentacyclic triterpenoid that is oleanane substituted at the 3beta-position by a hydroxy group and containing a double bond between positions 12 and 13. It is one of the most commonly occurring triterpenoids in higher plants.

Biological Activity

Triterpene th at has broad-spectrum analgesic properties for which the underlying mechanism is poorly understood.

in vivo

β-Amyrin (4 mg/kg, p.o., daily, 5 days) ameliorates object recognition memory deficit and neurogenesis impairments in the hippocampus of Aβ-induced AD model mice[1].
β-Amyrin (20-100 μg, i.p.) inhibits carrageenan-induced paw edema of rats[2].
β-Amyrin (20-80 mg/kg, i.g., daily, 5 days) has a potent efficacy in protecting against BLM-induced mice pulmonary fibrosis via suppressing inflammatory response and oxidative stress[3].
Pharmacokinetic parameters of β-Amyrin in rats

β-Amyrin standard IV (group 3)β-Amyrin standard oral dose (group 2)
Dose (mg kg?1) 1 3300 (equivalent of 3mg kg?1 β-amyrin)
V (ml kg?1) 1317
AUC0→24 h (min μg ml?1) 41110.6 47.3
Cl (ml min?1 kg?1)2.04
t1/2λZ (h)10.210.3 8.3
MRT0→24 h (h) (h)88.5 8.7
Cmax (ng ml?1) (h) (h)18.775
tmax (h)-3 (n = 2) or 5 (n = 1)3 (n = 3) or 5 (n = 1)
F (%)0.863.83
Animal Model:Male CD-1 mice, 26-28 g, 6 weeks old. 5 μL of Aβ was acutely injected into the left lateral ventricle by hand[1].
Dosage:4 mg/kg
Administration:p.o., daily, 5 days
Result:Increased number of transitions between the light and dark compartments.
Increased the total exploration time on the light compartment of the apparatus and the time spent in open arms.
Ameliorated the reduction of neurogenesis.
Animal Model: Adult male rats of Sprague–Dawley strain, weighing 150-180 g. Carrageenan induces edema in the hind paw of the rat[2].
Dosage:20, 50, 100 μg/kg
Administration:i.p.
Result:Significant decreased edema by in a dose dependent manner.
Animal Model: Adult male rats of Sprague–Dawley strain, weighing 150-180 g. Carrageenan induces Use Bleomycin (BLM) (HY-108345), 5mg/kg, one-time intratracheally injection, in 50μL saline per mouse to induce the marine model of pulmonary fibrosis[3].
Dosage: 20, 40, 80 mg/kg
Administration:i.g., daily, 5 days
Result:Promoted the values of SO2 and PO2 and inhibited the value of PCO2.
Significantly improved inflammatory cell infiltration, the thickened alveolar septum and the lesion collapses of the alveoli and formation of flaky lung tissue.

target

GABA Receptor | P450 (e.g. CYP17) | cAMP | PKC | PKA | PGE | TNF-α | Antifection

beta-Amyrin Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

beta-Amyrin Suppliers

Shanghai Taopu Industrial Co., LTD
Tel
159-00573766 18018507602
Email
394643792@qq.com
Country
China
ProdList
4328
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
Huzhou ZhanShu Biotechnology Co.,Ltd
Tel
0572-8889530 18167260939
Email
zsubio@163.com
Country
China
ProdList
392
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Wuhan TCASChem Technology Co., Ltd.
Tel
027-86697669 13986148687
Fax
86-027-86697669
Email
sales@tcaschem.com
Country
China
ProdList
3993
Advantage
55
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3988
Advantage
66
More
Less

View Lastest Price from beta-Amyrin manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
beta-Amyrin 559-70-6
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-27
Shaanxi Dideu Medichem Co. Ltd
Product
β-Amyrin 559-70-6
Price
US $0.00-0.00/KG
Min. Order
100g
Purity
99%+
Supply Ability
200 tons
Release date
2019-12-27
Shaanxi Dideu Medichem Co. Ltd
Product
β-Amyrin 559-70-6
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
100 tons
Release date
2020-01-15

559-70-6, beta-AmyrinRelated Search:


  • B-AMYRIN
  • BETA-AMYRIN
  • AMYRIN, B-
  • (3BETA)-OLEAN-12-EN-3-OL
  • 12-OLEANEN-3-BETA-OL
  • 12-OLEANIN-3-BETA-OL
  • OLEAN-12-EN-3BETA-OL
  • OLEAN-12-EN-3B-OL
  • beta-AMYRIN hplc
  • beta-Amyrenol
  • Olean-12-en-3-ol
  • Olean-12-en-3-ol, (3beta)-
  • B-AMYRIN WITH HPLC
  • (3S,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-ol
  • 3b-Hydroxyolean-12-ene
  • b-Amyrenol
  • Olean-12-en-3-ol, (3b)-
  • 5α-Olean-12-en-3β-ol
  • β-Amyrine
  • Einecs 209-204-6
  • Nsc 527971
  • Olean-12-en-3-ol, (3beta)- (9ci)
  • β-Amyrin,Olean-12-en-3β-ol
  • AMYRIN, BETA-(SH)
  • beta-aMyin
  • Olean-12-en-3-ol, (3β)-
  • β-Amyrin
  • TIANFUCHEM--High purity beta-Amyrin oxide factory price
  • AMYRIN, BETA-
  • β-Amyrin-RM
  • (3S,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-ol
  • 559-70-6
  • C30H50O
  • Chromatography
  • Natural Compounds
  • Life Sciences
  • Analytical Chromatography Product Catalog
  • Analytical Standards
  • Building block
  • Tri-Terpenoids