alpha-Cyclopentylmandelic acid

Product Name: alpha-Cyclopentylmandelic acid
CAS No.: 427-49-6
Chemical Name: alpha-Cyclopentylmandelic acid
Synonyms: 2-Cyclopentyl-2-hydroxy-2-phenylacetic acid;CYCLOPENTYL MANDELIC ACID;Mandelic acid, alpha-cyclopentyl;Glycopyrronium Bromide EP Impurity J;CM ACID;pha-CycL;TIMTEC-BB SBB010054;2-CYCLOPENTYL MANDELIC ACI;Glycopyrrolate Impurity 15;α-Cyclopentylmandelic acid
CBNumber: CB1751794
Molecular Formula: C13H16O3
Formula Weight: 220.27
MOL File: 427-49-6.mol

More

Less

alpha-Cyclopentylmandelic acid Property

Melting point:: 144-150 °C
Boiling point:: 110 °C (0.5 mmHg)
Density: 1.247±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 3.53±0.25(Predicted)
form: Solid
color: White to pale brown
InChI: InChI=1S/C13H16O3/c14-12(15)13(16,11-8-4-5-9-11)10-6-2-1-3-7-10/h1-3,6-7,11,16H,4-5,8-9H2,(H,14,15)
InChIKey: WFLUEQCOAQCQLP-UHFFFAOYSA-N
SMILES: C(C1CCCC1)(C1C=CC=CC=1)(O)C(=O)O
LogP: 2.770 (est)
CAS DataBase Reference: 427-49-6(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: C,Xi
Risk Statements: 34-41-37/38
Safety Statements: 45-36/37/39-26-39
RIDADR: 3261
WGK Germany: 3
HazardClass: IRRITANT
PackingGroup: III
HS Code: 29163990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2467
Product name: Glycopyrrolate Related Compound C
Purity: pharmaceutical secondary standard
Packaging: 50MG
Price: $718
Updated: 2024/03/01

Sigma-Aldrich

Product number: 706396
Product name: α-Cyclopentylmandelic acid
Purity: 97%
Packaging: 5g
Price: $76.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1296042
Product name: Glycopyrrolate Related Compound C
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25mg
Price: $1490
Updated: 2024/03/01

TCI Chemical

Product number: C2394
Product name: alpha-Cyclopentyl-DL-mandelic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $45
Updated: 2024/03/01

TCI Chemical

Product number: C2394
Product name: alpha-Cyclopentyl-DL-mandelic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $200
Updated: 2024/03/01

More

Less

alpha-Cyclopentylmandelic acid Chemical Properties,Usage,Production

Chemical Properties

white to beige powder

Uses

intermediate for Glycopyrronium Bromide, Oxyphencyclimine HCl, Oxypyrronium Bromide

Uses

2-Cyclopentyl-2-hydroxy-2-phenylacetic Acid is an impurity of Glycopyrrolate (G657000), a novel pharmaceutical compound based on PDE IV inhibitors; used in the treatment of respiratory complaints. It is used in the synthesis of muscarinic M3 receptor antagonists.

Research

Resolving racemic alpha-cyclopentylmandelic acid by a chemical resolution method by using L-Tyrosine methyl ester and (R)-alpha-phenylethylamine as resolution reagents to respectively prepare (S)-alpha-cyclopentylmandelic acid and (R)-alpha-cyclopentylmandelic acid; and carrying out esterification reaction to respectively obtain chiral intermediates (S)/(R)-alpha-cyclopentylmethyl mandelate. Multistage enantioselective liquid-liquid extraction (ELLE) of α--cyclopentyl-mandelic acid (α-CPMA) enantiomers using hydroxyethyl-β-cyclodextrin (HE-β-CD) as extractant was studied in a cascade of centrifugal contactor separators (CCSs)[1].

References

[1] Panliang Zhang. “Study on enantioseparation of α-cyclopentyl-mandelic acid enantiomers using continuous liquid-liquid extraction in centrifugal contactor separators: Experiments and modeling.” Chemical Engineering and Processing - Process Intensification 107 (2016): Pages 168-176.

alpha-Cyclopentylmandelic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

alpha-Cyclopentylmandelic acid Suppliers

Americas 1 Belgium 1 Canada 1 China 264 Europe 1 Germany 3 India 18 Japan 2 Russia 1 Slovakia 1 United Kingdom 7 United States 38 Global 338

Acros Organics

Tel: --
Fax: --
Email: info@acros.com
Country: Belgium
ProdList: 6772
Advantage: 81

More

Less

View Lastest Price from alpha-Cyclopentylmandelic acid manufacturers

Anhui Dexinjia Biopharm Co., Ltd

Product: alpha-Cyclopentylmandelic acid 427-49-6
Price: US $100.00-2000.00/KG
Min. Order: 100g
Purity: no less than 98%
Supply Ability: 1MT per month
Release date: 2021-01-12

Hebei Dangtong Import and export Co LTD

Product: alpha-Cyclopentylmandelic acid 427-49-6
Price: US $970.00-955.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 100Tons
Release date: 2023-03-06

Hebei Weibang Biotechnology Co., Ltd

Product: alpha-Cyclopentylmandelic acid 427-49-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-18

427-49-6, alpha-Cyclopentylmandelic acidRelated Search:

4-Methoxyphenylacetic acid Ethyl 2-(Chlorosulfonyl)acetate Folic acid 2-Hydroxyphenylacetic acid Citric acid DL-Mandelic acid CHLOROPHOSPHONAZO III α-Lipoic Acid Stearic acid 4-Hydroxyphenylacetic acid Alpha-Cyclopentylmandelic Acid Methyl Ester 2-Cyclohexylmandelic acid Ascoric Acid Benzoylformic acid LPHE-009 glycopyrronium bromide Methyl (R)-(-)-cyclopentylmandelate CYCLOPENTYL PHENYL KETONE

ALPHA-CYCLOPENTYLMANDELIC ACID

CM ACID

CYCLOPENTYL-HYDROXY-PHENYL-ACETIC ACID

CYCLOPENTYL MANDELIC ACID

CYCLOPENTYLPHENYLGLYCOLIC ACID

TIMTEC-BB SBB010054

a-Cyclo Pentyl Mandelic acid

2-CYCLOPENTYL MANDELIC ACID

2-Cyclopentyl-2-hydroxy-2-phenylacetic acid

2-hydroxy-2-cyclopentyl-2-phenylacetic acid

α-Cyclopentyl-α-hydroxybenzeneacetic acid

alpha-Cyclopentylmandelic acid,98%

alpha-Cyclopentyl-DL-mandelic Acid

2-CYCLOPENTYL MANDELIC ACI

alpha-CyclopentylMandelic acidCyclopentylphenylglycolic acid

Glycopyrrolate Related Compound C (25 mg) (2-Cyclopentyl-2-hydroxy-2-phenylacetic acid)

alpha-CyclopentylMandelic acid, 98% 5GR

Benzeneacetic acid, a-cyclopentyl-a-hydroxy-

alpha-CyclopentylMandelic acid SynonyMs Cyclopentylphenylglycolic acid

cyclopentylphenylglycolic acid cyclopentylphenylglycolic acid

α-Cyclopentyl-DL-Mandelic Acid

Glycopyrrolate Related CoMpound C

Glycopyrrolate Impurity 15

Glycopyrrolate USP Related Compound C

Glycopyrronium Bromide EP Impurity J

ALPHA-CYCLOPENTYLMANDELIC ACID CM ACID

Cyclopentylphenylglykolsure

α-Cyclopentylmandelic acid≥ 99% (Titration)

alpha-Cyclopentylmandelic acid 97%

2-cyclopentyl-2-hydroxy-2-phenyl-ethanoic acid

Mandelic acid, alpha-cyclopentyl

α-Cyclopentyl-DL-mandelic Acid &gt

pha-CycL

Glycopyrrolate EP Impurity J

CMPA =Cyclopentylmandelic acid Purity:98% (2.5 Kg X 3 batches + 3 Kg 4 th batch) 2weeks

α-Cyclopentylmandelic acid

Cyclopentyl mandelic acid(Glycopyrrolate Related compound C)

TIANFUCHEM--427-49-6--alpha-Cyclopentylmandelic acid

α-Cyclopentyl-DL-mandelic Acid

Glycopyrrolate Related Compound C (2-Cyclopentyl-2-hydroxy-2-phenylacetic acid) (1296042)

alpha-CYCLOPENTYL MANDELIC ACID Extra Pure

Grononium bromide impurity I

Benzeneacetic acid, α-cyclopentyl-α-hydroxy-

Glycopyrronium Bromide EP Impurity J (Glycopyrrolate USP Related Compound C)

2-Cyclopentyl-2-hydroxyphenylacetic acid

Glycopyrrolate Related Compound-C / Glycopyrronium Bromide EP impurity J

Glycopyrronium Bromide Impurity

Glycopyrronium Bromide Impurity 15

427-49-6

Building Blocks

C13 to C42+

Carbonyl Compounds

Carboxylic Acids

Chemical Synthesis

Organic Building Blocks

Intermediate