(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
- Product Name
- (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
- CAS No.
- 17857-14-6
- Chemical Name
- (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
- Synonyms
- 3-Carbox;(3-CarboxypropyL;3-Carboxypropyltriphenylphosph;(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM;3-propylcarboxyltriphenylphosphine bromide;3-Carboxypropyl triphenyl phosphanium bromide;(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE;(3-Propanecarboxy)triphenylphosphonium bromide;3-Carboxypropyl triphenylphosphonium bromide,97%;3-Carboxypropyltriphenylphosphonium bromide 98+%
- CBNumber
- CB1755484
- Molecular Formula
- C22H22BrO2P
- Formula Weight
- 429.29
- MOL File
- 17857-14-6.mol
(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE Property
- Melting point:
- 244-247 °C(lit.)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Crystalline Powder, Crystals, or Flakes
- color
- White
- Water Solubility
- Soluble in water. soluble in ethanol.
- Sensitive
- Hygroscopic
- BRN
- 4173599
- InChI
- InChI=1S/C22H21O2P.BrH/c23-22(24)17-10-18-25(19-11-4-1-5-12-19,20-13-6-2-7-14-20)21-15-8-3-9-16-21;/h1-9,11-16H,10,17-18H2;1H
- InChIKey
- NKVJKVMGJABKHV-UHFFFAOYSA-N
- SMILES
- [P+](CCCC(=O)O)(C1=CC=CC=C1)(C1C=CC=CC=1)C1=CC=CC=C1.[Br-]
- CAS DataBase Reference
- 17857-14-6(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 349720
- Product name
- (3-Carboxypropyl)triphenylphosphonium bromide
- Purity
- 98%
- Packaging
- 25g
- Price
- $99.3
- Updated
- 2025/07/31
- Product number
- 349720
- Product name
- (3-Carboxypropyl)triphenylphosphonium bromide
- Purity
- 98%
- Packaging
- 100g
- Price
- $307
- Updated
- 2025/07/31
- Product number
- C1635
- Product name
- (3-Carboxypropyl)triphenylphosphonium Bromide
- Purity
- >95.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $61
- Updated
- 2025/07/31
- Product number
- C181500
- Product name
- (3-Carboxypropyl)triphenylphosphonium Bromide
- Packaging
- 10g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 6676-9-X3
- Product name
- 3-Carboxypropyltriphenylphosphonium bromide
- Purity
- 98.0%
- Packaging
- 100g
- Price
- $136
- Updated
- 2021/12/16
(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE Chemical Properties,Usage,Production
Chemical Properties
White powder and granules
Uses
suzuki reaction
Uses
(3-Carboxypropyl)triphenylphosphonium Bromide is a reagent used in the preparation of sphingosine 1-phosphate-1 receptor antagonists. Also used in the synthesis of mitochondrial vitamin E metabolites and other mitochondrial targets in the study of mitochodrial functions. Also used in the preparation of benzosuberene analogs that inhibit tubulin assembly and demonstrate cytotoxicity.
Uses
(3-Carboxypropyl)triphenylphosphonium bromide is used as antimalarial agents, antimycobacterial agents,antifungal agents, inhibitors of protein tyrosine phosphatase.
reaction suitability
reaction type: C-C Bond Formation
Synthesis
2623-87-2
603-35-0
17857-14-6
General procedure: 4-Bromobutyric acid (1 eq.) and triphenylphosphine (1 eq.) were dissolved in 300 mL of toluene under argon protection and heated to reflux for 48 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure to remove the solvent. The target product (3-propylcarboxy)triphenylphosphonium bromide was obtained by crystallization and purification of the residue from a suitable solvent.
References
[1] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 1, p. 567 - 579
[2] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 21, p. 5088 - 5102
[3] Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2002, vol. 57, # 3, p. 335 - 337
[4] Tetrahedron Letters, 2016, vol. 57, # 10, p. 1083 - 1086
[5] Journal of the American Chemical Society, 2018, vol. 140, # 17, p. 5805 - 5813
(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE Suppliers
- Tel
- --
- Fax
- --
- brunschwig@brunschwig.nl
- Country
- The Netherlands
- ProdList
- 4996
- Advantage
- 67
View Lastest Price from (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE manufacturers
- Product
- (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE 17857-14-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-02
- Product
- (3-Carboxypropyl)triphenylphosphoniuM bromide 17857-14-6
- Price
- US $1.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2020-01-14
- Product
- (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE 17857-14-6
- Price
- US $8.00-0.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09