(5-Carboxypentyl)(triphenyl)phosphonium bromide

Product Name: (5-Carboxypentyl)(triphenyl)phosphonium bromide
CAS No.: 50889-29-7
Chemical Name: (5-Carboxypentyl)(triphenyl)phosphonium bromide
Synonyms: (5-CarboxypentyL;(5-CARBOXYAMYL)TRIPHENYLPHOSPHONIUM BROMIDE;(5-CARBOXYPENTYL)TRIPHENYLPHOSPHONIUM BROMIDE;（5-Carboxybutyl）(triphenyl)phosphonium bromide;(5-Carboxypentyl)triphenylphosphoniumbromide,97%;5-carboxypentyltriphenylphosphonium bromide, 98 %;(5-Carboxypentyl)(triphenyl)phosphonium bromide 97%;(5-carboxypentyl)triphenyl-Phosphonium bromide (1:1);(6-Hydroxy-6-oxo-hexyl)-triphenyl-phosphonium bromide;Phosphonium, (5-carboxypentyl)triphenyl-, bromide (1:1)
CBNumber: CB5259203
Molecular Formula: C24H26BrO2P
Formula Weight: 457.34
MOL File: 50889-29-7.mol

More

Less

(5-Carboxypentyl)(triphenyl)phosphonium bromide Property

Melting point:: 197-201 °C
storage temp.: Inert atmosphere,Room Temperature
solubility: Soluble in Chloroform and Methanol.
form: Solid
color: White to Off-White
Sensitive: Hygroscopic
InChI: InChI=1S/C24H25O2P.BrH/c25-24(26)19-11-4-12-20-27(21-13-5-1-6-14-21,22-15-7-2-8-16-22)23-17-9-3-10-18-23;/h1-3,5-10,13-18H,4,11-12,19-20H2;1H
InChIKey: JUWYRPZTZSWLCY-UHFFFAOYSA-N
SMILES: [P+](CCCCCC(=O)O)(C1C=CC=CC=1)(C1=CC=CC=C1)C1C=CC=CC=1.[Br-]
CAS DataBase Reference: 50889-29-7(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 26-36-36/37/39-22
WGK Germany: 3
HS Code: 2931599090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R648523
Product name: (5-CARBOXYPENTYL)(TRIPHENYL)PHOSPHONIUM BROMIDE
Purity: AldrichCPR
Packaging: 25MG
Price: $185
Updated: 2025/07/31

TCI Chemical

Product number: C3113
Product name: (5-Carboxypentyl)triphenylphosphonium Bromide
Purity: >96.0%(T)
Packaging: 5g
Price: $99
Updated: 2025/07/31

TRC

Product number: C178900
Product name: (5-Carboxypentyl)triphenylphosphonium Bromide
Packaging: 2.5g
Price: $1355
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: ING0003208
Product name: (5-CARBOXYPENTYL)(TRIPHENYL)PHOSPHONIUM BROMIDE
Purity: 95.00%
Packaging: 2.5G
Price: $1520
Updated: 2021/12/16

Ark Pharm

Product number: AK110766
Product name: (5-Carboxypentyl)triphenylphosphonium Bromide
Purity: 97%
Packaging: 25g
Price: $35
Updated: 2021/12/16

More

Less

(5-Carboxypentyl)(triphenyl)phosphonium bromide Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

It is used in medicine and as pharmaceutical intermediate. It is also employed as catalyst.

Uses

(5-Carboxypentyl)(triphenyl)phosphonium bromide is used in medicine and as pharmaceutical intermediate. It is also employed as catalyst.
Reactant for:

Preparation of inhibitor of protein tyrosine phosphatase 1B for treatment of diabetes and obesity.
Synthesis of folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity.
Preparation of peptide nucleic acids (PNA) with high specific activity.
Synthesis of roseophilin via Wittig/aldol methodology.

Synthesis

4224-70-8

603-35-0

50889-29-7

General procedure for the synthesis of 5-carboxypentyltriphenylphosphonium bromide from 6-bromohexanoic acid and triphenylphosphine: 6-bromohexanoic acid (10.00 g, 51.27 mmol) and triphenylphosphonium (14.12 g, 53.83 mmol) were dissolved in freshly distilled acetonitrile (50 mL) and the reaction mixture refluxed for 48 h under vigorous stirring. Upon completion of the reaction, the solution was cooled to room temperature and precipitation of Wittig salt was induced by scraping the inner wall of the glass reactor. The resulting white solid product was collected by filtration and washed with ether to give the final 5-carboxypentyltriphenylphosphonium bromide in 98% (22.87 g) yield. The structure of the product was confirmed by 1H NMR (400 MHz, CD3OD): δ 1.62-1.72 (m, 6H), 2.29 (t, 2H), 3.40-3.47 (m, 2H), 7.76-7.91 (m, 15H).

References

[1] Journal of Organic Chemistry, 1995, vol. 60, # 2, p. 321 - 330
[2] Analytical Chemistry, 2006, vol. 78, # 1, p. 71 - 81
[3] Journal of Organic Chemistry, 2004, vol. 69, # 14, p. 4615 - 4625
[4] Journal of Natural Products, 2001, vol. 64, # 11, p. 1426 - 1429
[5] Patent: WO2008/30532, 2008, A2. Location in patent: Page/Page column 41

(5-Carboxypentyl)(triphenyl)phosphonium bromide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(5-Carboxypentyl)(triphenyl)phosphonium bromide Suppliers

Americas 1 Belgium 1 Canada 1 China 184 Europe 1 France 2 Germany 5 India 4 Japan 3 Slovakia 1 Switzerland 1 The Netherlands 2 United Kingdom 11 United States 25 Global 242

Nanjing Confidence Chemical Co.,Ltd.

Tel: 025-86208213 、86208225 15951683105
Email: 57304476@qq.com
Country: China
ProdList: 145
Advantage: 58

Hangzhou Aiken New Materials Co., Ltd

Tel: 15258847994 15258847994
Email: 1624352@qq.com
Country: China
ProdList: 248
Advantage: 58

LINYI CONNECT CHEMICAL TECHNOLOGY CO.,LTD

Tel: 0523-84506864 15152665088
Email: sales@lvyuchem.com
Country: China
ProdList: 153
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

More

Less

View Lastest Price from (5-Carboxypentyl)(triphenyl)phosphonium bromide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (5-Carboxypentyl)(triphenyl)phosphonium bromide 50889-29-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2025-09-04

Henan Aochuang Chemical Co.,Ltd.

Product: (5-Carboxypentyl)(triphenyl)phosphonium bromide 50889-29-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

Henan Fengda Chemical Co., Ltd

Product: (5-Carboxypentyl)(triphenyl)phosphonium bromide 50889-29-7
Price: US $8.00-0.80/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

50889-29-7, (5-Carboxypentyl)(triphenyl)phosphonium bromideRelated Search:

(4-BROMOBENZYL)TRIPHENYLPHOSPHONIUM BROMIDE (4-Carboxybutyl)triphenylphosphonium bromide (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE Triphenylphosphine Tetrabutylphosphonium bromide Sodium bromate (FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE Ethidium bromide Allyl bromide Rocuronium bromide Phosphorus tribromide Chlorodiphenylphosphine Tetrakis(triphenylphosphine)platinum Methyl bromide HEXYLTRIPHENYLPHOSPHONIUM BROMIDE PENTYLTRIPHENYLPHOSPHONIUM BROMIDE hexyldiphenylphosphine (5-Carboxypentyl)(triphenyl)phosphonium bromide

(5-CARBOXYPENTYL)TRIPHENYLPHOSPHONIUM BROMIDE

(5-CARBOXYAMYL)TRIPHENYLPHOSPHONIUM BROMIDE

5-carboxypentyltriphenylphosphonium bromide, 98 %

(5-Carboxypentyl)triphenylphosphoniumbromide,97%

(5-Carboxypentyl)(triphenyl)phosphonium bromide 50889-29-7

(5-Carboxypentyl)(triphenyl)phosphonium bromide IN Stock

(5-Carboxypentyl)(triphenyl)phosphonium bromide 97%

(5-CarboxypentyL

（5-Carboxybutyl）(triphenyl)phosphonium bromide

(6-Hydroxy-6-oxo-hexyl)-triphenyl-phosphonium bromide

Phosphonium, (5-carboxypentyl)triphenyl-, bromide (1:1)

(5-carboxypentyl)triphenyl-Phosphonium bromide (1:1)

(5-Carboxypentyl)triphenylphosphonium bromide - [C90119]

50889-29-7

50889-29-2

C24H26BrO2P

HO2CCH25PC6H53Br

C6H53PBrCH25COOH

C-C Bond Formation

Synthetic Reagents

Wittig Reagents

Olefination

All Aliphatics

Miscellaneous Compounds

Aliphatics

Wittig Reagents