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4-Nitrophenyl isocyanate

Product Name
4-Nitrophenyl isocyanate
CAS No.
100-28-7
Chemical Name
4-Nitrophenyl isocyanate
Synonyms
ai3-28253;4-Nitrophenyl;TIMTEC-BB SBB006628;4-Nitrophenyl isocya;4-Nitrophenylcarbimide;4-NITROPHENYL ISOCYANATE;P-NITROPHENYL ISOCYANATE;4-Isocyanatonitrobenzene;PARA-NITROPHENYLISOCYANATE;1-isocyanato-4-nitro-benzen
CBNumber
CB1757004
Molecular Formula
C7H4N2O3
Formula Weight
164.12
MOL File
100-28-7.mol
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4-Nitrophenyl isocyanate Property

Melting point:
56-59 °C(lit.)
Boiling point:
137-138 °C11 mm Hg(lit.)
Density 
1.5018 (rough estimate)
refractive index 
1.5300 (estimate)
Flash point:
>110°C
storage temp. 
2-8°C
solubility 
soluble in Benzene,Toluene
form 
Crystalline Solid
color 
Yellow
Water Solubility 
Insoluble in water.
Sensitive 
Moisture Sensitive
BRN 
389516
CAS DataBase Reference
100-28-7(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-isocyanato-4-nitro-(100-28-7)
EPA Substance Registry System
p-Nitrophenyl isocyanate (100-28-7)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38-42
Safety Statements 
22-26-36/37/39-45
RIDADR 
2206
WGK Germany 
3
RTECS 
DA3692500
F 
10-19-21
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29291090
Toxicity
LD50 orl-rat: 1600 mg/kg NTIS** OTS0528342
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
269425
Product name
4-Nitrophenyl isocyanate
Purity
97%
Packaging
5g
Price
$47.2
Updated
2023/06/20
Sigma-Aldrich
Product number
269425
Product name
4-Nitrophenyl isocyanate
Purity
97%
Packaging
25g
Price
$183
Updated
2023/06/20
TCI Chemical
Product number
I0129
Product name
4-Nitrophenyl Isocyanate (contains varying amounts of polymers)
Purity
>98.0%(GC)
Packaging
5g
Price
$108
Updated
2023/06/20
TCI Chemical
Product number
I0129
Product name
4-Nitrophenyl Isocyanate (contains varying amounts of polymers)
Purity
>98.0%(GC)
Packaging
25g
Price
$313
Updated
2023/06/20
Alfa Aesar
Product number
A11194
Product name
4-Nitrophenyl isocyanate, 97%
Packaging
5g
Price
$38.6
Updated
2023/06/20
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4-Nitrophenyl isocyanate Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline solid

Uses

4-Nitrophenyl isocyanate is used as pharmaceutical intermediates. 4-Nitrophenyl isocyanate was used in the synthesis of 2-(5-methyl-3,4-diphenyl-1H-pyrrole-2-carbonyl)-N-(4-nitrophenyl)hydrazinecarboxamide.

Safety Profile

A poison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits toxic vapors of NOx.

Purification Methods

Distil the isocyanate in a vacuum, and/or recrystallise it from pet ether (b 28-38o), *C6H6/pet ether (m 58o) or CCl4 (m 56-57o). [Beilstein 12 H 725, 12 III 1630.]

4-Nitrophenyl isocyanate Preparation Products And Raw materials

Raw materials

Hydrochloric acid 4-Nitroaniline

Preparation Products

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4-Nitrophenyl isocyanate Suppliers

China 1 Global 1
Fuxin Pharmaceutical
Tel
+86-021-021-50872116 +8613122107989
Email
contact@fuxinpharm.com
Country
China
ProdList
10032
Advantage
58

100-28-7, 4-Nitrophenyl isocyanateRelated Search:

Isocyanatocyclohexane Propyl isocyanate Benzyl isocyanate 4-Chlorophenyl isocyanate BENZOYL ISOCYANATE ISOCYANIC ACID Hexyl isocyanate 2-METHYL-4-NITROPHENYL ISOCYANATE 2-CHLORO-4-NITROPHENYL ISOCYANATE 4-Nitrophenyl isocyanate 2-METHOXY-4-NITROPHENYL ISOCYANATE 2-METHYL-5-NITROPHENYL ISOCYANATE Phenyl isocyanate ISOCYANATE cyanic acid 3-NITROPHENYL ISOCYANATE,M-NITROPHENYL ISOCYANATE 4-METHYL-3-NITROPHENYL ISOCYANATE 4,5-DIMETHYL-2-NITROPHENYL ISOCYANATE,4,5-DIMETHYL-2-NITROPHENYL ISOCYANATE, 9 7%,4,5-DIMETHYL-2-NITROPHENYL ISOCYANATE 97%

  • 1-isocyanato-4-nitro-benzen
  • ai3-28253
  • benzene,1-isocyanato-4-nitro-
  • Isocyanic acid, p-nitrophenyl ester
  • (contains varying aMounts of polyMers)
  • 4-Nitrophenyl Isocyanate&nbsp
  • 4-Nitrophenyl isocyanate, 98% 25GR
  • 4-Nitrophenyl isocyanate, 98% 5GR
  • 4-Nitrophenyl isocya
  • 4-Nitrophenyl isocyanate 97%
  • 4-Nitrophenylisocyanate,97%
  • Isocyanic acid, p-nitrophenyl ester (8CI)
  • 4-Nitrophenyl isocyanate≥ 99% (GC)
  • isocyanicacid,p-nitrophenylester
  • 4-NITROPHENYL ISOCYANATE
  • P-NITROPHENYL ISOCYANATE
  • TIMTEC-BB SBB006628
  • ISOCYANIC ACID 4-NITROPHENYL ESTER
  • 4-Nitrophenylcarbimide
  • 1-ISOCYANATO-4-NITRO-BENZENE
  • 4-Nitrophenyl
  • PARA-NITROPHENYLISOCYANATE
  • 4-Isocyanatonitrobenzene
  • 4-Nitrophenyl Isocyanate (contains varying amounts of polymers)
  • 4-Nitrophenyl isocyanate,98%
  • 4-NitrophenylIsocyanate(containsvaryingamountsofpolymers)&gt
  • 4-?Nitrophenyl Isocyanate (1-Isocyanato-4-nitrobenzene)
  • 4-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-80-THIOSEMICARBAZIDE
  • 100-28-7
  • O2NC6H4NCO
  • Organic Building Blocks
  • Nitrogen Compounds
  • ARYL ISOCYANATE
  • Building Blocks
  • Isocyanates
  • Isocyanates
  • Phenyls & Phenyl-Het
  • Phenyls & Phenyl-Het
  • Nitrogen Compounds
  • Organic Building Blocks
  • Carbohydrates & Derivatives