Tregalizumab

Product Name: Tregalizumab
CAS No.: 1207446-68-1
Chemical Name: Tregalizumab
Synonyms: Tregalizumab;Tregalizumab (anti-CD4);Research Grade Tregalizumab
CBNumber: CB18080834
Formula Weight: 0
MOL File: Mol file

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Tregalizumab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Tregalizumab Chemical Properties,Usage,Production

Uses

Tregalizumab is a humanized anti-human CD4 monoclonal antibody (IgG1 type) that selectively activates the suppressive properties of regulatory T cells (Tregs) in vitro. Tregalizumab can be used in the research of autoimmune diseases (resulting from insufficient Treg activity) and allergies[1][2][3].

References

[1] K?nig M, et al. Tregalizumab - A Monoclonal Antibody to Target Regulatory T Cells. Front Immunol. 2016 Jan 25;7:11. DOI:10.3389/fimmu.2016.00011
[2] Vogel S, et al. Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells. Sci Rep. 2015 Dec 16;5:18308. DOI:10.1038/srep18308
[3] Helling B, et al. A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway. Immunol Cell Biol. 2015 Apr;93(4):396-405. DOI:10.1038/icb.2014.102

Tregalizumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Tregalizumab Suppliers

China 17 United States 1 Global 18

Shanghai YuanYe Biotechnology Co., Ltd.

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1207446-68-1, TregalizumabRelated Search:

Atidortoxumab Suptavumab Rivabazumab Radretumab Tenatumomab Ociperlimab Concizumab Trevogrumab Oxelumab Amubarvimab

Tregalizumab

Research Grade Tregalizumab

Tregalizumab (anti-CD4)

1207446-68-1