4-BROMO-2-IODOPHENOL
Application- Product Name
- 4-BROMO-2-IODOPHENOL
- CAS No.
- 207115-22-8
- Chemical Name
- 4-BROMO-2-IODOPHENOL
- Synonyms
- 2-Iodo-4-bromophenol;4-BROMO-2-IODOPHENOL;Phenol, 4-bromo-2-iodo-;4-Bromo-2-iodophenol98%;4-Bromo-2-iodophenol 98%;4-BROMO-2-IODOPHENOL ISO 9001：2015 REACH
- CBNumber
- CB1838862
- Molecular Formula
- C6H4BrIO
- Formula Weight
- 298.9
- MOL File
- 207115-22-8.mol
4-BROMO-2-IODOPHENOL Property
- Melting point:
- 90℃ (ethanol )
- Boiling point:
- 243.0±25.0℃ (760 Torr)
- Density
- 2.369±0.06 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 100.8±23.2℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- powder to crystal
- pka
- 7.94±0.18(Predicted)
- color
- White to Light yellow to Light orange
Safety
- HS Code
- 2908190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B4957
- Product name
- 4-Bromo-2-iodophenol
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $106
- Updated
- 2025/07/31
- Product number
- B4957
- Product name
- 4-Bromo-2-iodophenol
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $255
- Updated
- 2025/07/31
- Product number
- B683913
- Product name
- 4-Bromo-2-iodophenol
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- OR52087
- Product name
- 4-Bromo-2-iodophenol
- Purity
- 98%
- Packaging
- 1g
- Price
- $41
- Updated
- 2021/12/16
- Product number
- 2601-S-X1
- Product name
- 4-Bromo-2-iodophenol
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
4-BROMO-2-IODOPHENOL Chemical Properties,Usage,Production
Application
4-Bromo-2-iodophenol, also known as 2-iodo-4-bromophenol, is an organic intermediate that can be prepared by nitration and reduction of p-bromophenol followed by diazotization and iodination.
Synthesis
533-58-4
207115-22-8
General procedure for the synthesis of 4-bromo-2-iodophenol (4) from 2-iodophenol: 2-iodophenol (11 g, 50 mmol) was dissolved in a solvent mixture of dichloromethane (DCM, 200 mL) and methanol (MeOH, 100 mL). Subsequently, tetrabutylammonium tribromide (TBATB, 25.31 g, 52.5 mmol) was added in batches over 10 min. The reaction mixture was stirred at room temperature for 2 h before the reaction was quenched with 1N hydrochloric acid (HCl, 200 mL). The organic layer (DCM layer) was separated and the aqueous layer was extracted twice more with dichloromethane (DCM). All organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by fast column chromatography (silica gel, 50%-100% dichloromethane/hexane gradient elution) to afford the target product 4-bromo-2-iodophenol (10.2 g, 68% yield).
References
[1] Tetrahedron, 2015, vol. 71, # 35, p. 5946 - 5951
[2] Journal of Organic Chemistry, 2013, vol. 78, # 17, p. 8680 - 8688
[3] Organic Letters, 2015, vol. 17, # 22, p. 5666 - 5669
[4] Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1931, vol. 192, p. 1037
[5] Canadian Journal of Chemistry, 1965, vol. 43, p. 650 - 658
4-BROMO-2-IODOPHENOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BROMO-2-IODOPHENOL manufacturers
- Product
- 4-BROMO-2-IODOPHENOL 207115-22-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-07-05
- Product
- 4-BROMO-2-IODOPHENOL 207115-22-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-09