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Tribenoside

Product Name
Tribenoside
CAS No.
10310-32-4
Chemical Name
Tribenoside
Synonyms
TBGF;Venex;Alven;21401-Ba;Glyvenol;Glyvenal;Glivenol;Tohcuron;Ba 21401;Flebosan
CBNumber
CB1842212
Molecular Formula
C29H34O6
Formula Weight
478.58
MOL File
10310-32-4.mol
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Tribenoside Property

alpha 
D26 +8° (chloroform)
Boiling point:
bp1.2 270-280°
Density 
1.19±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Practically insoluble in water, very soluble in acetone, in methanol and in methylene chloride.
pka
13.01±0.70(Predicted)
color 
Pale Yellow to Light Yellow
InChIKey
ULLNJSBQMBKOJH-VIVFLBMVSA-N
CAS DataBase Reference
10310-32-4
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Safety

Toxicity
LD50 oral in rat: > 20gm/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0000165
Product name
Tribenoside
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000165
Price
$220
Updated
2024/03/01
Usbiological
Product number
293301
Product name
Ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside
Packaging
5g
Price
$382
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
O106695
Product name
Ethyl3-5-6-tri-O-benzyl-D-glucofuranoside
Packaging
5G
Price
$395
Updated
2021/12/16
Biosynth Carbosynth
Product number
ME02540
Product name
Ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside
Packaging
50g
Price
$425
Updated
2021/12/16
Biosynth Carbosynth
Product number
ME02540
Product name
Ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside
Packaging
100g
Price
$750
Updated
2021/12/16
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Tribenoside Chemical Properties,Usage,Production

Chemical Properties

Yellowish to pale yellow, clear, viscous liquid.

Originator

Glyvenol,Ciba,W. Germany,1967

Uses

Tribenoside is a vasoprotective drug. It’s used in the treatment of hemorrhoids as it has mild anti-inflammatory and wound healing properties.

Uses

Sclerosing agent.

Definition

ChEBI: (3R,4R,5R)-5-[(1R)-1,2-bis(phenylmethoxy)ethyl]-2-ethoxy-4-phenylmethoxy-3-oxolanol is a glycoside.

Manufacturing Process

4.9 g of 3,5,6-tribenzyl-1,2-isopropylidene glucofuranose are kept overnight at room temperature with 100 cc of N-ethanolic hydrochloric acid. Evaporation under vacuum at below 50°C is then carried out and the residue taken up in 150 cc of chloroform. The chloroform solution is thoroughly washed with sodium bicarbonate solution, dried with calcined sodium sulfate and evaporated under vacuum. The oily residue is then distilled under vacuum with a free flame. In this manner there is obtained the ethyl-3,5,6-tribenzyl_x0002_D-glucofuranoside of boiling point 270°C to 275°C under 1 mm pressure. The glucofuranose used as starting material is obtained as follows: 8.8 g of 1,2-isopropylidene-D-glucofuranose and 50.6 g of benzyl chloride are treated with a total of 28 g of potassium hydroxide in portions with cooling and stirring. The mixture is then stirred for 3 hours at 80°C to 90°C. Working up from chloroform solution and distillation at 250°C to 260°C under 0.1 mm pressure give 8.9 g of 1,2-isopropylidene-3,5,6-tribenzyl-D-glucofuranose.

Therapeutic Function

Topical venotonic

Hazard

Low toxicity by ingestion.

Contact allergens

This drug is used for the treatment, both topical and oral, of hemorrhoids. It leads to benzo?c acid, that is contained in Myroxylon pereirae as well, and could be the sensitizer.

Tribenoside Preparation Products And Raw materials

Raw materials

Preparation Products

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Tribenoside Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Carbosynth Limited
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6581
Advantage
61
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
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View Lastest Price from Tribenoside manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tribenoside 10310-32-4
Price
US $0.00/G
Min. Order
100G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-20
shandong perfect biotechnology co.ltd
Product
Tribenoside 10310-32-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
1000kg
Release date
2023-07-06
Hebei Yanxi Chemical Co., Ltd.
Product
Tribenoside 10310-32-4
Price
US $100.00/kgkg
Min. Order
1kgkg
Purity
0.99
Supply Ability
100
Release date
2023-09-20

10310-32-4, TribenosideRelated Search:


  • Glivenol
  • Glucofuranoside, ethyl 3,5,6-tri-O-benzyl- (7CI)
  • Glucofuranoside, ethyl 3,5,6-tri-O-benzyl-, D- (8CI)
  • Glyvenal
  • Glyvenol
  • Hemocuron
  • TBGF
  • Tribenzoside
  • Venex
  • 1-O-Ethyl-3-O,5-O,6-O-tribenzyl-D-glucofuranose
  • 21401-Ba
  • Tohcuron
  • (3R,4R,5R)-4-(Benzyloxy)-5-((R)-1,2-bis(benzyloxy)ethyl)-2-ethoxytetrahydrofuran-3-ol
  • D-Glucofuranoside,ethyl 3,5,6-tris-O-(phenylMethyl)-
  • -1,2-bis(benzyloxy)
  • -2-ethoxytetrahydrofuran-3-ol
  • (3R,4R,5R)-5-[1,2-Bis(phenylmethoxy)ethyl]-2-ethoxy-4-(phenylmethoxy)oxolan-3-ol
  • ETHYL-3,5,6-TRI-O-BENZYL-D-GLUCOFURANOSIDE
  • Alven
  • Ba 21401
  • D-Glucofuranoside, ethyl 3,5,6-tris-O-(phenylmethyl)- (9CI)
  • Flebosan
  • TRIBENOSIDE
  • (3R,4R,5R)-4-(benzyloxy)-5-[(1R)-1,2-bis(benzyloxy)ethyl]-2-ethoxyoxolan-3-ol
  • Tribenoside (3R,4R,5R)-5-[1,2-Bis(phenylmethoxy)ethyl]-2-ethoxy-4-(phenylmethoxy)oxolan-3-ol
  • Tribenoside CRS
  • Tribenoside API
  • Tribenzyl glycoside
  • 10310-32-4
  • C29H34O6