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2-Chloro-1-propanol

Product Name
2-Chloro-1-propanol
CAS No.
78-89-7
Chemical Name
2-Chloro-1-propanol
Synonyms
VPM-4G;Nsc122672;2-Chloropropanol;2-chloro-1-propano;MONOCHLOROPROPANOL;2-Chloro-1-propanol;2-chloropropan-1-ol;2-chloro-propan-1-ol;PROPYLENECHLORHYDRIN;2-chloropropylalcohol
CBNumber
CB1851586
Molecular Formula
C3H7ClO
Formula Weight
94.54
MOL File
78-89-7.mol
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2-Chloro-1-propanol Property

Melting point:
<25 °C
Boiling point:
bp 133-134°
Density 
d20 1.103
refractive index 
nD20 1.4362
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Sparingly)
pka
14.16±0.10(Predicted)
form 
Oil
color 
Colourless
Odor
pleasant odor
Exposure limits
No exposure limit is set. However, on the basis of its similar toxic properties to ethylene chlorohydrin, a TLV-TWA air 10 ppm (approximately 40 mg/m3) is recommended.
LogP
0.268 (est)
CAS DataBase Reference
78-89-7
EPA Substance Registry System
2-Chloro-1-propanol (78-89-7)
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Safety

RIDADR 
2611
HazardClass 
6.1(a)
PackingGroup 
II
Hazardous Substances Data
78-89-7(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 0.22 ml/kg; by skin penetration in rabbits: 0.48 ml/kg, Smyth et al., Am. Ind. Hyg. Assoc. J. 30, 470 (1969)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H312Harmful in contact with skin

H319Causes serious eye irritation

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FC146292
Product name
2-Chloro-1-propanol
Packaging
100mg
Price
$125
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC146292
Product name
2-Chloro-1-propanol
Packaging
250mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC146292
Product name
2-Chloro-1-propanol
Packaging
500mg
Price
$400
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0199099
Product name
2-CHLORO-1-PROPANOL
Purity
95.00%
Packaging
5MG
Price
$496.2
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC146292
Product name
2-Chloro-1-propanol
Packaging
1g
Price
$600
Updated
2021/12/16
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2-Chloro-1-propanol Chemical Properties,Usage,Production

Chemical Properties

Propylene chlorohydrin is a colorless liquid.

Chemical Properties

Colorless liquid; mild, nonresidual odor. Soluble in water and alcohol.

Uses

In preparation of propylene oxide, q.v.

Uses

Propylene β-chlorohydrin is used in the pro duction of propylene oxide.

Uses

2-Chloropropanol is used as a solvent in the composition and method for removing a coating from a surface. 2-Chloropropanol is used as an organic solvent in liquid cleaner for the removal of post-etch residues from microsprocessors.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 4353, 1950 DOI: 10.1021/ja01166a005

General Description

Clear colorless liquid with a pleasant odor.

Air & Water Reactions

Water soluble.

Reactivity Profile

2-Chloro-1-propanol may be sensitive to prolonged exposure to light. 2-Chloro-1-propanol can react with oxidizing agents. .

Hazard

Moderate fire risk. Toxic by ingestion and skin absorption. Liver damage. Questionable car- cinogen.

Health Hazard

Propylene β-chlorohydrin is a moderatelytoxic compound having irritant actions onthe skin and eyes. Instilling 2.2 mg of liquidcaused severe eye irritation in rabbits. It cancause poisoning via ingestion, inhalation, andskin absorption. Exposure to 500 ppm for4 hours was lethal to rats. The lethal dosein dogs by oral intake was 200 mg/kg. Thetarget organs are the CNS, gastrointestinalsystem, liver, and kidney.
LD50 value, skin (rabbits): 529 mg/kg
Studies conducted to determine increasedrisks of pancreatic and lymphopoietic can cer among workers in ethylene and propylene chlorohydrin production remained inconclu sive and have given inconsistent findings(Olsen et al. 1997).

Fire Hazard

2-Chloro-1-propanol is flammable.

Safety Profile

Poison by ingestion. Moderately toxic by inhalation and skin contact. A skin and severe eye irritant. Flammable liquid when exposed to heat, flame, or powerful oxidizers. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of Cl-.

Potential Exposure

This material is used in organic synthesis; to make other chemicals.

Shipping

UN2611Propylene chlorohydrin, Hazard class: 6.1; Labels: 6.1-Poisonous materials, 3-Flammable liquid.

Incompatibilities

Vapor may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Alcohols are sensitive to light and oxi- dation. It is unstable in solution. It undergoes hydrolysis in aqueous buffers. Contact with alkali metals, nitrides, and strong reducing agents may form flammable and/or toxic gases. May react with anhydrides forming acids and esters, generating noticeable heat, and also with oxoacids and carboxylic acids to form esters plus water, but the heat of reaction in the latter case typically is low. May initiate the polymerization of isocyanates and epoxides.

Waste Disposal

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

2-Chloro-1-propanol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-1-propanol Suppliers

Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
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57
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
XinYao(Shenzhen) Biological Technology Co., Ltd.
Tel
0755-89880280
Fax
0755-89880280
Email
3004662104@qq.com
Country
China
ProdList
1829
Advantage
58
Hubei xin bonus chemical co. LTD
Tel
86-13657291602
Fax
027-59338440
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
22963
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QUALITY CONTROL SOLUTIONS LTD.
Tel
0755-66853366; 13670046396
Email
ORDERS@QCSRM.COM
Country
China
ProdList
18882
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
17691182729 18161915376
Email
1046@dideu.com
Country
China
ProdList
10007
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58
Cato Research Chemicals Inc.
Tel
020-81960175-877 18933936954
Email
tianwen.zhan@cato-chem.com
Country
China
ProdList
7734
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58
Cheng Du Micxy Chemical Co.,Ltd
Tel
028-85632863 18048500443
Fax
028-85632863
Email
sales@micxy.com
Country
China
ProdList
10474
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58
Shanghai Aitixi Biotechnology Co., Ltd
Tel
18721763493 18721763493
Email
2493172863@qq.com
Country
China
ProdList
1003
Advantage
58
Cato Research Chemicals Inc.
Tel
13342851930
Email
3008394369@qq.com
Country
China
ProdList
15603
Advantage
58

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