Methyl 2-chloroacetoacetate

Product Name: Methyl 2-chloroacetoacetate
CAS No.: 4755-81-1
Chemical Name: Methyl 2-chloroacetoacetate
Synonyms: Methyl 2-chloro-3-oxobutanoate;Apixaban Impurity 210;2-chloro acetylacetate;METHYL 2-CHLOROACETOACETATE;Methyle2-chloroacetoacetate;METHYL 2-CHLORO-3-OXOBUTANATE;Methyl 2-chloroacetoacetate,95%;Methyl 2-Chloroacetoacetate >methyl alpha-chloroacetoacetate;Chloroacetoaceticacidmethylester
CBNumber: CB8737542
Molecular Formula: C5H7ClO3
Formula Weight: 150.56
MOL File: 4755-81-1.mol

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Methyl 2-chloroacetoacetate Property

Melting point:: -33--32.7 °C (lit.)
Boiling point:: 137 °C (lit.)
Density: 1.236 g/mL at 25 °C (lit.)
refractive index: n20/D 1.446(lit.)
Flash point:: 161 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: Liquid
pka: 7.89±0.46(Predicted)
color: Clear yellow
Water Solubility: 50 g/L (20 ºC)
InChI: 1S/C5H7ClO3/c1-3(7)4(6)5(8)9-2/h4H,1-2H3
InChIKey: GYQRIAVRKLRQKP-UHFFFAOYSA-N
SMILES: COC(=O)C(Cl)C(C)=O
CAS DataBase Reference: 4755-81-1(CAS DataBase Reference)
NIST Chemistry Reference: Butanoic acid, 2-chloro-3-oxo-, methyl ester(4755-81-1)
EPA Substance Registry System: Methyl 2-chloroacetoacetate (4755-81-1)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38-22
Safety Statements: 26-27-28-36/37/39-37/39
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
TSCA: TSCA listed
HazardClass: 8
PackingGroup: III
HS Code: 29183000
Storage Class: 10 - Combustible liquids
Hazard Classifications: Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 183911
Product name: Methyl 2-chloroacetoacetate
Packaging: 25g
Price: $198
Updated: 2023/06/20

TCI Chemical

Product number: C1219
Product name: Methyl 2-Chloroacetoacetate
Purity: >95.0%(GC)
Packaging: 25g
Price: $75
Updated: 2025/07/31

TCI Chemical

Product number: C1219
Product name: Methyl 2-Chloroacetoacetate
Purity: >95.0%(GC)
Packaging: 250g
Price: $444
Updated: 2025/07/31

TRC

Product number: M295562
Product name: Methyl 2-chloroacetoacetate
Packaging: 5g
Price: $55
Updated: 2021/12/16

TRC

Product number: M295562
Product name: Methyl 2-chloroacetoacetate
Packaging: 25g
Price: $165
Updated: 2021/12/16

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Methyl 2-chloroacetoacetate Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

Methyl 2-chloroacetoacetate was used in one-pot synthesis of 2-arylimidazole-4-carboxylic acids. It was also used in synthesis of 3,5-disubstituted 1,2,4-triazoles.

Synthesis Reference(s)

Synthesis, p. 188, 1987 DOI: 10.1055/s-1987-27886

Methyl 2-chloroacetoacetate Preparation Products And Raw materials

Raw materials

Preparation Products

MEVINPHOS

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Methyl 2-chloroacetoacetate Suppliers

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View Lastest Price from Methyl 2-chloroacetoacetate manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

Product: Methyl 2-Chloroacetoacetate 4755-81-1
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-14

Shaanxi Dideu Medichem Co. Ltd

Product: Methyl 2-Chloroacetoacetate 4755-81-1
Price: US $1.00-1.50/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100000KG
Release date: 2024-08-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: Methyl 2-chloroacetoacetate 4755-81-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

4755-81-1, Methyl 2-chloroacetoacetateRelated Search:

Ethyl 2-chloroacetoacetate ACETYLSALICYLIC ACID METHYL ESTER Methyl acetate Ethyl 4,4,4-trifluoroacetoacetate Methyl acetoacetate Methyl levulinate Methyl acrylate Kresoxim-methyl Chloromethyl pivalate Acetoxyacetic acid Ethyl acetoacetate Bensulfuron methyl Methyl chloroacetate tert-Butyl acetoacetate Methylparaben METHYL THIOPHENE-2-CARBOXYLATE Thiophanate-methyl Methyl

2-chloro-3-oxo-butanoicacimethylester

Methyl 2-chloro-3-oxobutanoate

Chloroacetoaceticacidmethylester

Butanoic acid, 2-chloro-3-oxo-, methyl ester

2-chloro-3-oxo-butyric acid methyl ester

2-Acetyl-2-chloroacetic acid methyl ester

Methyl 2-chloroacetoacetate,95%

2-chloro acetylacetate

2-CHLOROACETOACETIC ACID METHYL ESTER

2-chloro-3-oxobutanoic acid, methyl ester

METHYL 2-CHLORO-3-OXOBUTANATE

METHYL 2-CHLOROACETOACETATE

Methyle2-chloroacetoacetate

(2S)-2-chloro-3-oxobutanoic acid methyl ester

Methyl 2-Chloroacetoacetate &gt

Apixaban Impurity 210

methyl alpha-chloroacetoacetate

2-Chloroacetoacetate methyl ester

4755-81-1

4775-81-1

CH3COCHClCO2CH3

Building Blocks

Carbonyl Compounds

C2 to C5

Organic Building Blocks

Esters

Building Blocks

C2 to C5

Carbonyl Compounds

Chemical Synthesis

Organic Building Blocks

C2 to C5

Carbonyl Compounds

Esters