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Methyl 2-chloroacetoacetate

Product Name
Methyl 2-chloroacetoacetate
CAS No.
4755-81-1
Chemical Name
Methyl 2-chloroacetoacetate
Synonyms
Methyl 2-chloro-3-oxobutanoate;Apixaban Impurity 210;2-chloro acetylacetate;METHYL 2-CHLOROACETOACETATE;Methyle2-chloroacetoacetate;METHYL 2-CHLORO-3-OXOBUTANATE;Methyl 2-chloroacetoacetate,95%;Methyl 2-Chloroacetoacetate >methyl alpha-chloroacetoacetate;Chloroacetoaceticacidmethylester
CBNumber
CB8737542
Molecular Formula
C5H7ClO3
Formula Weight
150.56
MOL File
4755-81-1.mol
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Methyl 2-chloroacetoacetate Property

Melting point:
-33--32.7 °C (lit.)
Boiling point:
137 °C (lit.)
Density 
1.236 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.446(lit.)
Flash point:
161 °F
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
Liquid
pka
7.89±0.46(Predicted)
color 
Clear yellow
Water Solubility 
50 g/L (20 ºC)
CAS DataBase Reference
4755-81-1(CAS DataBase Reference)
NIST Chemistry Reference
Butanoic acid, 2-chloro-3-oxo-, methyl ester(4755-81-1)
EPA Substance Registry System
Methyl 2-chloroacetoacetate (4755-81-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38-22
Safety Statements 
26-27-28-36/37/39-37/39
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
3
HazardClass 
8
PackingGroup 
III
HS Code 
29183000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
183911
Product name
Methyl 2-chloroacetoacetate
Packaging
25g
Price
$198
Updated
2023/06/20
TCI Chemical
Product number
C1219
Product name
Methyl 2-Chloroacetoacetate
Purity
>95.0%(GC)
Packaging
25g
Price
$75
Updated
2024/03/01
TCI Chemical
Product number
C1219
Product name
Methyl 2-Chloroacetoacetate
Purity
>95.0%(GC)
Packaging
250g
Price
$444
Updated
2024/03/01
TRC
Product number
M295562
Product name
Methyl 2-chloroacetoacetate
Packaging
25g
Price
$165
Updated
2021/12/16
TRC
Product number
M295562
Product name
Methyl 2-chloroacetoacetate
Packaging
5g
Price
$55
Updated
2021/12/16
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Methyl 2-chloroacetoacetate Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

Methyl 2-chloroacetoacetate was used in one-pot synthesis of 2-arylimidazole-4-carboxylic acids. It was also used in synthesis of 3,5-disubstituted 1,2,4-triazoles.

Synthesis Reference(s)

Synthesis, p. 188, 1987 DOI: 10.1055/s-1987-27886

Methyl 2-chloroacetoacetate Preparation Products And Raw materials

Raw materials

Preparation Products

MEVINPHOS
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Methyl 2-chloroacetoacetate Suppliers

Americas 1 Belgium 1 China 112 Europe 1 Finland 1 Germany 3 India 9 Japan 3 Switzerland 5 United Kingdom 3 United States 17 Global 156
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
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View Lastest Price from Methyl 2-chloroacetoacetate manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Methyl 2-Chloroacetoacetate 4755-81-1
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-14
Shaanxi Dideu Medichem Co. Ltd
Product
Methyl 2-Chloroacetoacetate 4755-81-1
Price
US $1.00-1.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
100000KG
Release date
2024-08-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
Methyl 2-chloroacetoacetate 4755-81-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

4755-81-1, Methyl 2-chloroacetoacetateRelated Search:

Ethyl 2-chloroacetoacetate ACETYLSALICYLIC ACID METHYL ESTER Methyl acetate Ethyl 4,4,4-trifluoroacetoacetate Methyl acetoacetate Methyl levulinate Methyl acrylate Kresoxim-methyl Chloromethyl pivalate Acetoxyacetic acid Ethyl acetoacetate Bensulfuron methyl Methyl chloroacetate tert-Butyl acetoacetate Thiophanate-methyl Methylparaben METHYL THIOPHENE-2-CARBOXYLATE Methyl

  • 2-chloro-3-oxo-butanoicacimethylester
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  • 2-chloro acetylacetate
  • 2-CHLOROACETOACETIC ACID METHYL ESTER
  • 2-chloro-3-oxobutanoic acid, methyl ester
  • METHYL 2-CHLORO-3-OXOBUTANATE
  • METHYL 2-CHLOROACETOACETATE
  • Methyle2-chloroacetoacetate
  • (2S)-2-chloro-3-oxobutanoic acid methyl ester
  • Methyl 2-Chloroacetoacetate &gt
  • Apixaban Impurity 210
  • methyl alpha-chloroacetoacetate
  • 4755-81-1
  • 4775-81-1
  • CH3COCHClCO2CH3
  • Building Blocks
  • Carbonyl Compounds
  • C2 to C5
  • Organic Building Blocks
  • Esters
  • Building Blocks
  • C2 to C5
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • C2 to C5
  • Carbonyl Compounds
  • Esters