10H-pyrido(3,2-b)(1,4)benzothiazine
- Product Name
- 10H-pyrido(3,2-b)(1,4)benzothiazine
- CAS No.
- 261-96-1
- Chemical Name
- 10H-pyrido(3,2-b)(1,4)benzothiazine
- Synonyms
- NSC 277720;1-Azaphenothiazine;1-Azaphenothiazine>Isothipendyl Impurity 1;Isothipendyl Impurity 2;10H-benzo[e]pyrido[3,2-b][1;PYRIDO[3,2-B][1,4]BENZOTHIAZINE;1H-Pyrido[3,2-b][1,4]benzothiazine;10H-pyrido(3,2-b)(1,4)benzothiazine;10H-benzo[e]pyrido[3,2-b][1,4]thiazine
- CBNumber
- CB1875186
- Molecular Formula
- C11H8N2S
- Formula Weight
- 200.26
- MOL File
- 261-96-1.mol
10H-pyrido(3,2-b)(1,4)benzothiazine Property
- Melting point:
- 110.0 to 114.0 °C
- Boiling point:
- 370°C(lit.)
- Density
- 1.293
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Dichloromethane (Slightly), DMSO (Slightly)
- pka
- 4.24±0.20(Predicted)
- form
- Solid
- color
- Yellow to Dark Yellow
- InChI
- InChI=1S/C11H8N2S/c1-2-5-9-8(4-1)13-11-10(14-9)6-3-7-12-11/h1-7H,(H,12,13)
- InChIKey
- UKDZROJJLPDLDO-UHFFFAOYSA-N
- SMILES
- S1C2=CC=CC=C2NC2=NC=CC=C12
Safety
- HS Code
- 2934.99.4400
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A2862
- Product name
- 1-Azaphenothiazine
- Purity
- >98.0%(GC)(T)
- Packaging
- 200mg
- Price
- $66
- Updated
- 2025/07/31
- Product number
- A2862
- Product name
- 1-Azaphenothiazine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $224
- Updated
- 2025/07/31
- Product number
- P991655
- Product name
- 10H-Pyrido[3,2-b][1,4]benzothiazine
- Packaging
- 1g
- Price
- $250
- Updated
- 2021/12/16
- Product number
- P991655
- Product name
- 10H-Pyrido[3,2-b][1,4]benzothiazine
- Packaging
- 10g
- Price
- $495
- Updated
- 2021/12/16
- Product number
- 66863
- Product name
- 10H-Pyrido[3,2-β][1,4]benzothiazine
- Packaging
- 25g
- Price
- $2750
- Updated
- 2021/12/16
10H-pyrido(3,2-b)(1,4)benzothiazine Chemical Properties,Usage,Production
Uses
10H-Pyrido[3,2-b][1,4]benzothiazine has potential anti-cancer ability as seen through studies.
Synthesis
95873-97-5
261-96-1
General procedure for the synthesis of azaphenothiazine from the compound (CAS: 95873-97-5): 15.0 g (119.82 mmol) of intermediate (C) was suspended with 4.36 g (119.82 mmol) of hydrochloric acid in 470 mL of ethanol and the reaction was carried out at reflux for 12 h at 70 °C under nitrogen protection. After completion of the reaction, extraction was carried out with dichloromethane and distilled water and the organic layer was filtered through silica gel. After concentrating the organic solvent, it was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether = 7:3, v/v) to give 20.64 g of intermediate (D) in 86% yield.
References
[1] Patent: KR2015/12906, 2015, A. Location in patent: Paragraph 0197; 0204-0205
[2] Journal of the American Chemical Society, 1958, vol. 80, p. 1651,1653
10H-pyrido(3,2-b)(1,4)benzothiazine Preparation Products And Raw materials
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View Lastest Price from 10H-pyrido(3,2-b)(1,4)benzothiazine manufacturers
- Product
- 10H-pyrido(3,2-b)(1,4)benzothiazine 261-96-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- bulk production
- Release date
- 2025-11-26
- Product
- 10H-pyrido(3,2-b)(1,4)benzothiazine 261-96-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-01