ChemicalBook > CAS DataBase List > 10H-pyrido(3,2-b)(1,4)benzothiazine

10H-pyrido(3,2-b)(1,4)benzothiazine

Product Name
10H-pyrido(3,2-b)(1,4)benzothiazine
CAS No.
261-96-1
Chemical Name
10H-pyrido(3,2-b)(1,4)benzothiazine
Synonyms
NSC 277720;1-Azaphenothiazine;1-Azaphenothiazine>Isothipendyl Impurity 1;Isothipendyl Impurity 2;10H-benzo[e]pyrido[3,2-b][1;PYRIDO[3,2-B][1,4]BENZOTHIAZINE;1H-Pyrido[3,2-b][1,4]benzothiazine;10H-pyrido(3,2-b)(1,4)benzothiazine;10H-benzo[e]pyrido[3,2-b][1,4]thiazine
CBNumber
CB1875186
Molecular Formula
C11H8N2S
Formula Weight
200.26
MOL File
261-96-1.mol
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10H-pyrido(3,2-b)(1,4)benzothiazine Property

Melting point:
110.0 to 114.0 °C
Boiling point:
370°C(lit.)
Density 
1.293
storage temp. 
Sealed in dry,Room Temperature
solubility 
Dichloromethane (Slightly), DMSO (Slightly)
pka
4.24±0.20(Predicted)
form 
Solid
color 
Yellow to Dark Yellow
InChI
InChI=1S/C11H8N2S/c1-2-5-9-8(4-1)13-11-10(14-9)6-3-7-12-11/h1-7H,(H,12,13)
InChIKey
UKDZROJJLPDLDO-UHFFFAOYSA-N
SMILES
S1C2=CC=CC=C2NC2=NC=CC=C12
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Safety

HS Code 
2934.99.4400
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2862
Product name
1-Azaphenothiazine
Purity
>98.0%(GC)(T)
Packaging
200mg
Price
$66
Updated
2025/07/31
TCI Chemical
Product number
A2862
Product name
1-Azaphenothiazine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$224
Updated
2025/07/31
TRC
Product number
P991655
Product name
10H-Pyrido[3,2-b][1,4]benzothiazine
Packaging
1g
Price
$250
Updated
2021/12/16
TRC
Product number
P991655
Product name
10H-Pyrido[3,2-b][1,4]benzothiazine
Packaging
10g
Price
$495
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
66863
Product name
10H-Pyrido[3,2-β][1,4]benzothiazine
Packaging
25g
Price
$2750
Updated
2021/12/16
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10H-pyrido(3,2-b)(1,4)benzothiazine Chemical Properties,Usage,Production

Uses

10H-Pyrido[3,2-b][1,4]benzothiazine has potential anti-cancer ability as seen through studies.

Synthesis

95873-97-5

261-96-1

General procedure for the synthesis of azaphenothiazine from the compound (CAS: 95873-97-5): 15.0 g (119.82 mmol) of intermediate (C) was suspended with 4.36 g (119.82 mmol) of hydrochloric acid in 470 mL of ethanol and the reaction was carried out at reflux for 12 h at 70 °C under nitrogen protection. After completion of the reaction, extraction was carried out with dichloromethane and distilled water and the organic layer was filtered through silica gel. After concentrating the organic solvent, it was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether = 7:3, v/v) to give 20.64 g of intermediate (D) in 86% yield.

References

[1] Patent: KR2015/12906, 2015, A. Location in patent: Paragraph 0197; 0204-0205
[2] Journal of the American Chemical Society, 1958, vol. 80, p. 1651,1653

10H-pyrido(3,2-b)(1,4)benzothiazine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 10H-pyrido(3,2-b)(1,4)benzothiazine manufacturers

Beijing CosmicKoda Chemical Technology Co.,Ltd
Product
10H-pyrido(3,2-b)(1,4)benzothiazine 261-96-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
bulk production
Release date
2025-11-26
Career Henan Chemical Co
Product
10H-pyrido(3,2-b)(1,4)benzothiazine 261-96-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-01

261-96-1, 10H-pyrido(3,2-b)(1,4)benzothiazineRelated Search:


  • PYRIDO[3,2-B][1,4]BENZOTHIAZINE
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  • 10H-benzo[e]pyrido[3,2-b][1
  • NSC 277720
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  • 10H-benzo[e]pyrido[3,2-b][1,4]thiazine
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  • 9-thia-2,4-diazatricyclo[8.4..3,?]tetradeca-1(14),3,5,7,1,12-hexaene
  • 10H-Pyrido[3,2-b][1,4]benzothiazine (6CI, 7CI, ACI)
  • 261-96-1