2-Amino-6-chloro-4-picoline
- Product Name
- 2-Amino-6-chloro-4-picoline
- CAS No.
- 51564-92-2
- Chemical Name
- 2-Amino-6-chloro-4-picoline
- Synonyms
- 6-Chloro-4-methylpyridin-2-amine;2-Amino-6-chloro-4-picoline;6-chloro-4-Methyl-2-PyridinaMine;2-AMino-6-chloro-4-Methylpyridine;2-Pyridinamine, 6-chloro-4-methyl-;2-Amino-6-chloro-4-methylpyridine 97+%;2-Amino-6-chloro-4-picoline ISO 9001:2015 REACH
- CBNumber
- CB1947155
- Molecular Formula
- C6H7ClN2
- Formula Weight
- 142.59
- MOL File
- 51564-92-2.mol
2-Amino-6-chloro-4-picoline Property
- Boiling point:
- 280.2±35.0 °C(Predicted)
- Density
- 1.260±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 3.42±0.35(Predicted)
- form
- solid
- color
- Yellow
- InChI
- InChI=1S/C6H7ClN2/c1-4-2-5(7)9-6(8)3-4/h2-3H,1H3,(H2,8,9)
- InChIKey
- NWQCZHMVYZDGQJ-UHFFFAOYSA-N
- SMILES
- C1(N)=NC(Cl)=CC(C)=C1
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A603555
- Product name
- 2-Amino-6-chloro-4-methylpyridine
- Packaging
- 1g
- Price
- $3025
- Updated
- 2021/12/16
- Product number
- A603555
- Product name
- 2-Amino-6-chloro-4-methylpyridine
- Packaging
- 5g
- Price
- $4125
- Updated
- 2021/12/16
- Product number
- HCH0049816
- Product name
- 2-AMINO-6-CHLORO-4-PICOLINE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $5082
- Updated
- 2021/12/16
- Product number
- 119020
- Product name
- 6-Chloro-4-methylpyridin-2-amine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1764
- Updated
- 2021/12/16
- Product number
- HCH0049816
- Product name
- 2-AMINO-6-CHLORO-4-PICOLINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $3753.75
- Updated
- 2021/12/16
2-Amino-6-chloro-4-picoline Chemical Properties,Usage,Production
Synthesis
1004294-60-3
51564-92-2
Step d: Synthesis of 6-chloro-4-methylpyridin-2-amine; N-(6-chloro-4-methylpyridin-2-yl) neopentanamide (500 mg, 2.21 mmol) was dissolved in 6M hydrochloric acid solution (40 mL) and the reaction was stirred at 90 °C for 6 h. The reaction was carried out at 90 °C for 2 h. The reaction was carried out at 90 °C for 1 h. The reaction was carried out at 90 °C for 2 h. The reaction was carried out at 90 °C for 2 h. The reaction was carried out at 90 °C for 2 h. The reaction was carried out at 90 °C for 2 h. The reaction was carried out at 90 °C for 2 h. Upon completion of the reaction, the mixture was cooled to room temperature and neutralized with sodium hydroxide solution to pH 10. Subsequently, the mixture was extracted with ethyl acetate, the organic phases were combined and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent being a mixed solution of petroleum ether and ethyl acetate (95:5, v/v) to afford 6-chloro-4-methylpyridin-2-amine (257 mg, 82% yield). The product was characterized by 1H NMR (CDCl3, 300 MHz): δ 6.52 (s, 1H), 6.26 (s, 1H), 2.23 (s, 3H).
References
[1] Patent: WO2008/141119, 2008, A2. Location in patent: Page/Page column 86-87
2-Amino-6-chloro-4-picoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-6-chloro-4-picoline manufacturers
- Product
- 2-Amino-6-chloro-4-picoline 51564-92-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-30
- Product
- 2-Amino-6-chloro-4-picoline 51564-92-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2020-01-02