Bendamustine
- Product Name
- Bendamustine
- CAS No.
- 97832-05-8
- Chemical Name
- Bendamustine
- Synonyms
- Bendamustine;Bendamustine USP/EP/BP;Phenol,5-iodo-7-methyl-;4-[5-[Bis(2-chloroethyl)amino]-1-methyl-benzimidazol-2-yl]butyric acid hydrochloride
- CBNumber
- CB1947357
- Molecular Formula
- C16H21Cl2N3O2.HCl
- Formula Weight
- 394.72
- MOL File
- 97832-05-8.mol
N-Bromosuccinimide Price
- Product number
- API0002176
- Product name
- CYTOSTASAN
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $648.83
- Updated
- 2021/12/16
- Product number
- API0002176
- Product name
- CYTOSTASAN
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $976.27
- Updated
- 2021/12/16
Bendamustine Chemical Properties,Usage,Production
Uses
Bendamustine is an intermediate in the synthesis of Bendamustine 3-Hydroxyprop-2-yl Ester (B132550), which is an impurity of anticancer drug Bendamustine Hydrochloride (B132500).
Enzyme inhibitor
This nitrogen mustard and anticancer drug (FWfree-acid = 358.26 g/mol; CAS 16506-27-7), also known by its code name SDX-105, its trade names Treanda?, Treakisym?, Ribomustin?, and Levact?, as well as by its systematic name 4-[5-[bis (2-chloroethyl) amino]-1-methylbenzimidazol-2- yl]butanoic acid, is a relatively nonspecific DNA alkylating agent that causes intra- and inter-strand cross-links. Bendamustine is used in the treatment of chronic lymphocytic leukemia (CLL), Hodgkin’s disease, non- Hodgkin’s lymphoma, multiple myeloma and lung cancer. Pharmacokinetics: After intravenous infusion, >95% of the drug becomes protein-bound, mainly to albumin; however, only free bendamustine is active. Bendamustine is metabolized by liver cytochrome p450, and elimination (renal) is biphasic, with an initial half-life of 6–10 minutes and a terminal half-life of approximately 30 minutes.
Bendamustine Preparation Products And Raw materials
Raw materials
Preparation Products
Bendamustine Suppliers
View Lastest Price from Bendamustine manufacturers
- Product
- Bendamustine 97832-05-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-05
- Product
- Bendamustine 97832-05-8
- Price
- US $20.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2020-11-14
- Product
- Bendamustine 97832-05-8
- Price
- US $1.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2019-08-30