3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone

Product Name: 3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone
CAS No.: 298207-77-9
Chemical Name: 3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone
Synonyms: WAY-357919;VEGFR-2-IN-37;1-(3-(5,6,7,8-4H-BENZO(4,5)THIENO(2,3-D)PYRIMIDIN-4-YLOXY)-PHENYL)-ETHANONE;1-[3-(5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4-yloxy)phenyl]ethanone;3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone;Ethanone, 1-[3-[(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)oxy]phenyl]-;1-(3-((5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)oxy)phenyl)ethan-1-one
CBNumber: CB19664840
Molecular Formula: C18H16N2O2S
Formula Weight: 324.4
MOL File: 298207-77-9.mol

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3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone Property

Melting point:: 148-149 °C
Boiling point:: 519.4±50.0 °C(Predicted)
Density: 1.305±0.06 g/cm3(Predicted)
pka: 2.07±0.20(Predicted)
form: Solid
color: Off-white to pink

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R423335
Product name: 1-(3-(5,6,7,8-4H-BENZO(4,5)THIENO(2,3-D)PYRIMIDIN-4-YLOXY)-PHENYL)-ETHANONE
Purity: AldrichCPR
Packaging: 50MG
Price: $30.7
Updated: 2025/07/31

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3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone Chemical Properties,Usage,Production

Uses

VEGFR-2-IN-37 (compound 12) is an inhibitor of VEGFR-2. The inhibition rate at 200 μM was approximately 56.9 μM. VEGFR-2-IN-37 is a potential inhibitor of human umbilical vein endothelial cell (HUVEC) proliferation[1].

References

[1] Perspicace E, et al. Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2). Eur J Med Chem. 2013 May;63:765-81. DOI:10.1016/j.ejmech.2013.03.022

3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone Suppliers

China 14 United States 2 Global 16

Shanghai YuanYe Biotechnology Co., Ltd.

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Tianjin Kailiqi Biotechnology Co., Ltd.

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Shanghai Haohong Pharmaceutical Co., Ltd.

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Bide Pharmatech Ltd.

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TargetMol Chemicals Inc.

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Henan Alpha Chemical Co., Ltd.

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Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd

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298207-77-9, 3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenoneRelated Search:

2,4-PyriMidinediaMine with linker N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE 3-[5-[2-[(2-Methoxyethyl)methylamino]ethoxy]-1H-indol-2-yl]-2(1H)-quinolinone 3-nitro-N-(8-quinolinyl)benzamide

3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone

1-[3-(5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4-yloxy)phenyl]ethanone

WAY-357919

Ethanone, 1-[3-[(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)oxy]phenyl]-

VEGFR-2-IN-37

1-(3-((5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)oxy)phenyl)ethan-1-one

1-(3-(5,6,7,8-4H-BENZO(4,5)THIENO(2,3-D)PYRIMIDIN-4-YLOXY)-PHENYL)-ETHANONE

298207-77-9