N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE

Product Name: N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE
CAS No.: 269390-69-4
Chemical Name: N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE
Synonyms: Valatinib;VEGFR-IN-1;Gefitinib-d;VEGFR IN 1,VEGFRIN1;VEGFR Tyrosine Kinase;VEGFR Tyrosine Kinase Inhibitor II;VEGF RECEPTOR TYROSINE KINASE INHIBITOR II;N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE;Benzamide, N-(4-chlorophenyl)-2-[(4-pyridinylmethyl)amino]-
CBNumber: CB7847754
Molecular Formula: C19H16ClN3O
Formula Weight: 337.8
MOL File: 269390-69-4.mol

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N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE Property

Boiling point:: 463.6±40.0 °C(Predicted)
Density: 1.331±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 25 mg/ml
form: A crystalline solid
pka: 12.62±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 676481
Product name: VEGFR Tyrosine Kinase Inhibitor II - CAS 269390-69-4 - Calbiochem
Packaging: 5MG
Price: $207
Updated: 2022/05/15

Cayman Chemical

Product number: 17654
Product name: VEGFR Tyrosine Kinase Inhibitor II
Purity: ≥98%
Packaging: 1mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 17654
Product name: VEGFR Tyrosine Kinase Inhibitor II
Purity: ≥98%
Packaging: 5mg
Price: $180
Updated: 2024/03/01

TRC

Product number: V756803
Product name: VEGFRTyrosineKinaseInhibitorII
Packaging: 2.5mg
Price: $270
Updated: 2021/12/16

TRC

Product number: V756803
Product name: VEGFRTyrosineKinaseInhibitorII
Packaging: 10mg
Price: $815
Updated: 2021/12/16

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N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE Chemical Properties,Usage,Production

Uses

VEGFR Tyrosine Kinase Inhibitor II is an agent that potently inhibits kinase activities of KDR, Flt-1 and c-Kit.

Biological Activity

Cell permeable: yes', 'Primary Target
Kinase activities of KDR, Flt-1 and c-Kit', 'Product competes with ATP.', 'Reversible: yes', 'Target IC50: 20 nM, 180 nM and 240 nM against kinase activities of KDR, Flt-1 and c-Kit, respectively

N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE Suppliers

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269390-69-4, N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDERelated Search:

2,4-PyriMidinediaMine with linker 3-[5-[2-[(2-Methoxyethyl)methylamino]ethoxy]-1H-indol-2-yl]-2(1H)-quinolinone 3-nitro-N-(8-quinolinyl)benzamide 3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE

VEGFR Tyrosine Kinase Inhibitor II

N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE

VEGF RECEPTOR TYROSINE KINASE INHIBITOR II

Valatinib

Benzamide, N-(4-chlorophenyl)-2-[(4-pyridinylmethyl)amino]-

VEGFR-IN-1

VEGFR Tyrosine Kinase

VEGFR IN 1,VEGFRIN1

Gefitinib-d

269390-69-4

Angiogenesis and Metastasis