3-nitro-N-(8-quinolinyl)benzamide

Product Name: 3-nitro-N-(8-quinolinyl)benzamide
CAS No.: 62802-77-1
Chemical Name: 3-nitro-N-(8-quinolinyl)benzamide
Synonyms: WAY-302159;VEGFR-2-IN-29;3-nitro-N-(8-quinolinyl)benzamide;3-Nitro-N-(quinolin-8-yl)benzamide;Inhibitor,VEGFR,quinoline amide,inhibit,WAY 302159,HUVEC,Vascular endothelial growth factor receptor,WAY302159
CBNumber: CB51960791
Molecular Formula: C16H11N3O3
Formula Weight: 293.27684
MOL File: 62802-77-1.mol

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3-nitro-N-(8-quinolinyl)benzamide Property

storage temp.: Store at -20°C
solubility: DMSO : 20 mg/mL (68.19 mM; ultrasonic and warming and heat to 60°C)
form: Solid
color: Light brown to brown

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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3-nitro-N-(8-quinolinyl)benzamide Chemical Properties,Usage,Production

Uses

VEGFR-2-IN-29 (Compound 5) is a VEGFR-2 inhibitor with an IC50 of 16.5 nM[1].

IC 50

VEGFR-2: 16.5 nM (IC₅₀)

References

[1] Yang Y, et al. Design, synthesis and biological evaluation of quinoline amide derivatives as novel VEGFR-2 inhibitors. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6653-6. DOI:10.1016/j.bmcl.2010.09.014

3-nitro-N-(8-quinolinyl)benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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3-nitro-N-(8-quinolinyl)benzamide Suppliers

China 21 The Netherlands 1 United States 3 Global 25

Shanghai YuanYe Biotechnology Co., Ltd.

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62802-77-1, 3-nitro-N-(8-quinolinyl)benzamideRelated Search:

2,4-PyriMidinediaMine with linker N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE 3-[5-[2-[(2-Methoxyethyl)methylamino]ethoxy]-1H-indol-2-yl]-2(1H)-quinolinone 3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone Quinazoline, 4-[(4-bromophenyl)methoxy]- 1H-1,2,4-Triazole-3-carboxamide, 1-(3-chloro-4-fluorophenyl)-N-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)- VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) 2-Quinazolinecarboxylic acid, 4-[3-fluoro-4-[[[(3-methylphenyl)amino]carbonyl]amino]phenoxy]-, ethyl ester Pazopanib Impurity 3 Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated 3-Pyridinecarbonitrile, 2-hydrazinyl-6-(2-naphthalenyl)-4-(4-nitrophenyl)-

3-nitro-N-(8-quinolinyl)benzamide

WAY-302159

3-Nitro-N-(quinolin-8-yl)benzamide

Inhibitor,VEGFR,quinoline amide,inhibit,WAY 302159,HUVEC,Vascular endothelial growth factor receptor,WAY302159

VEGFR-2-IN-29

62802-77-1