ChemicalBook > CAS DataBase List > Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester

Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester

Product Name
Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester
CAS No.
2455414-26-1
Chemical Name
Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester
Synonyms
VEGFR-2-IN-24;Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester
CBNumber
CB812989272
Molecular Formula
C28H23N3O6S
Formula Weight
529.56
MOL File
2455414-26-1.mol
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Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester Property

Density 
1.424±0.06 g/cm3(Predicted)
pka
12.80±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester Chemical Properties,Usage,Production

Uses

VEGFR-2-IN-24 is a potent VEGFR-2 inhibitor with IC50 value of 0.22 μM. VEGFR-2-IN-24 can be used for tumor research[1].

IC 50

VEGFR2: 0.22 μM (IC50)

References

[1] El-Adl K, et al. Design, synthesis, molecular docking and anticancer evaluations of 5-benzylidenethiazolidine-2,4-dione derivatives targeting VEGFR-2 enzyme. Bioorg Chem. 2020 Sep;102:104059. DOI:10.1016/j.bioorg.2020.104059

Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester Suppliers

China 1 United States 1 Global 2
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2455414-26-1, Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl esterRelated Search:

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  • Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester
  • VEGFR-2-IN-24
  • 2455414-26-1