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3-nitro-N-(8-quinolinyl)benzamide

Product Name
3-nitro-N-(8-quinolinyl)benzamide
CAS No.
62802-77-1
Chemical Name
3-nitro-N-(8-quinolinyl)benzamide
Synonyms
WAY-302159;VEGFR-2-IN-29;3-nitro-N-(8-quinolinyl)benzamide;3-Nitro-N-(quinolin-8-yl)benzamide;Inhibitor,VEGFR,quinoline amide,inhibit,WAY 302159,HUVEC,Vascular endothelial growth factor receptor,WAY302159
CBNumber
CB51960791
Molecular Formula
C16H11N3O3
Formula Weight
293.27684
MOL File
62802-77-1.mol
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3-nitro-N-(8-quinolinyl)benzamide Property

storage temp. 
Store at -20°C
solubility 
DMSO : 20 mg/mL (68.19 mM; ultrasonic and warming and heat to 60°C)
form 
Solid
color 
Light brown to brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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3-nitro-N-(8-quinolinyl)benzamide Chemical Properties,Usage,Production

Uses

VEGFR-2-IN-29 (Compound 5) is a VEGFR-2 inhibitor with an IC50 of 16.5 nM[1].

IC 50

VEGFR-2: 16.5 nM (IC50)

References

[1] Yang Y, et al. Design, synthesis and biological evaluation of quinoline amide derivatives as novel VEGFR-2 inhibitors. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6653-6. DOI:10.1016/j.bmcl.2010.09.014

3-nitro-N-(8-quinolinyl)benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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3-nitro-N-(8-quinolinyl)benzamide Suppliers

China 21 The Netherlands 1 United States 3 Global 25
Shanghai YuanYe Biotechnology Co., Ltd.
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62802-77-1, 3-nitro-N-(8-quinolinyl)benzamideRelated Search:

2,4-PyriMidinediaMine with linker N-(4-CHLOROPHENYL)-2-[(PYRIDIN-4-YLMETHYL)AMINO]BENZAMIDE 3-[5-[2-[(2-Methoxyethyl)methylamino]ethoxy]-1H-indol-2-yl]-2(1H)-quinolinone 3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone Quinazoline, 4-[(4-bromophenyl)methoxy]- 1H-1,2,4-Triazole-3-carboxamide, 1-(3-chloro-4-fluorophenyl)-N-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)- VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) 2-Quinazolinecarboxylic acid, 4-[3-fluoro-4-[[[(3-methylphenyl)amino]carbonyl]amino]phenoxy]-, ethyl ester Pazopanib Impurity 3 Benzoic acid, 4-[[4-[[2-[2,4-dioxo-5-(phenylmethylene)-3-thiazolidinyl]acetyl]amino]benzoyl]amino]-, ethyl ester VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated 3-Pyridinecarbonitrile, 2-hydrazinyl-6-(2-naphthalenyl)-4-(4-nitrophenyl)-

  • 3-nitro-N-(8-quinolinyl)benzamide
  • WAY-302159
  • 3-Nitro-N-(quinolin-8-yl)benzamide
  • Inhibitor,VEGFR,quinoline amide,inhibit,WAY 302159,HUVEC,Vascular endothelial growth factor receptor,WAY302159
  • VEGFR-2-IN-29
  • 62802-77-1