WILFORINE

Product Name: WILFORINE
CAS No.: 11088-09-8
Chemical Name: WILFORINE
Synonyms: WILFORINE;Wilforine-RM;26-Deoxywilfordine;Wilforine, 10 mM in DMSO;(8α)-8-(Acetyloxy)-2-O-benzoyl-2-O-deacetyl-8-deoxoevonimine;Evonimine, 8-(acetyloxy)-O2-benzoyl-O2-deacetyl-8-deoxo-, (8α)-;(8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-m;8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione,10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-,(8R,9R,10R,11S,1;(8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione;8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-
CBNumber: CB1994119
Molecular Formula: C43H49NO18
Formula Weight: 867.85
MOL File: 11088-09-8.mol

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WILFORINE Property

Melting point:: 158-163℃
Boiling point:: 871.5±65.0 °C(Predicted)
Density: 1.41
solubility: Soluble in methan
form: powder
pka: 11.70±0.70(Predicted)
color: White-yellowish
InChIKey: ZOCKGJZEUVPPPI-UHFFFAOYSA-N
SMILES: C(C12C(C(OC(C3C=CC=CC=3)=O)C3OC(C(CCC4=NC=CC=C4C(=O)OCC4(C)C(C(OC(=O)C)C1OC(=O)C)C(OC(=O)C)C2(C3(O)C)O4)C)=O)OC(=O)C)OC(=O)C

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Safety

Toxicity: LD50 intraperitoneal in mouse: 418mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: W498785
Product name: Wilforine
Packaging: 1mg
Price: $105
Updated: 2021/12/16

TRC

Product number: W498785
Product name: Wilforine
Packaging: 2.5mg
Price: $205
Updated: 2021/12/16

TRC

Product number: W498785
Product name: Wilforine
Packaging: 5mg
Price: $325
Updated: 2021/12/16

Usbiological

Product number: 361894
Product name: Wilforine
Packaging: 10mg
Price: $581
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594390
Product name: Wilforine
Packaging: 10mg
Price: $596.7
Updated: 2021/12/16

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WILFORINE Chemical Properties,Usage,Production

Description

Present in Tripterygiurn wilfordii Hook, this base forms colourless plates when crystallized from MeOH-Me2CO. It has [α]^{25/sup>_D + 30° (Me2CO).}

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Tripterygium wilfordii and Begonia truncatum.

Uses

Wilforine is a major bioactive sesquiterpene alkaloid extracted from Tripterygium wifordii Hook F. displaying anti-inflammatory activity.

Definition

ChEBI: An organic heteropentacyclic compound and pyridine alkaloid with formula C43H49NO18 originally isolated from the roots of Tripterygium wilfordii.

References

Beroza.,J. Arner. Chern. Soc., 74,3656 (1952) Beroza., ibid, 75,44 (1953)

WILFORINE Preparation Products And Raw materials

Raw materials

Preparation Products

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WILFORINE Suppliers

China 151 United Kingdom 1 United States 11 Global 163

Chengdu PFID reference Technology Co., Ltd

Tel: 028-82610909 15882229804
Email: pufeide@foxmail.com
Country: China
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Shanghai Moqi Biological Technology Co., LTD

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Email: 2702713455@qq.com
Country: China
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Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
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BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
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BioBioPha Co., Ltd.

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Fax: 0871-65215563
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Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
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S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-83725681-603
Fax: +86 755 28094224
Country: China
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MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
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Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 8000
Advantage: 58

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View Lastest Price from WILFORINE manufacturers

Career Henan Chemical Co

Product: Wilforine 11088-09-8
Price: US $9.80/KG
Min. Order: 1KG
Purity: ＞98%HPLC
Supply Ability: 20 tons
Release date: 2020-02-06

11088-09-8, WILFORINERelated Search:

MONOCROTALINE Triptolide Celastrol Sinomenine WITHANOLIDE B(P)(NEW) WITHANOLIDE A(P) 4-[2-[(1S,2R,4aS,7S,8aR)-4a-[(Acetyloxy)methyl]-1,2,3,4,4a,7,8,8a-octahydro-7-hydroxy-5-(hydroxymethyl)-1,2-dimethyl-1-naphthalenyl]ethyl]-2(5H)-furanone L-Lysine Progesterone Sophoridine Xanthine Triptonine B WILFORTRINE WILFORLIDE A Wilfornine A WILFORGINE Wilforol A Tangeretin

WILFORINE

(8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione

8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione,10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-,(8R,9R,10R,11S,1

(8α)-8-(Acetyloxy)-2-O-benzoyl-2-O-deacetyl-8-deoxoevonimine

(8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-m

26-Deoxywilfordine

8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-

Evonimine, 8-(acetyloxy)-O2-benzoyl-O2-deacetyl-8-deoxo-, (8α)-

Wilforine-RM

Wilforine, 10 mM in DMSO

11088-09-8

reagent

standard substance