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Eprazinone

Application
Product Name
Eprazinone
CAS No.
10402-90-1
Chemical Name
Eprazinone
Synonyms
EPRAZINONE;Eprazinone USP/EP/BP;Eprazinone (base and/or unspecified salts);1-(2-phenyl-2-ethoxy)ethyl-4-(2-benzoyl)propylpiperazine;1-(2-phenyl-2-ethoxyethyl)-4-(2-benzyloxypropyl)piperazine;2-(4-(beta-ethoxyphenethyl)-1-piperazinyl)methyl-propiophenon;β-[4-(β-Ethoxyphenethyl)-1-piperazinyl]-α-methylpropiophenone;3-(4-(beta-ethoxyphenethyl)-1-piperazinyl)-2-methylpropiophenone;3-(4-(2-Ethoxy-2-phenylethyl)piperazin-1-yl)-2-Methyl-1-phenylpropan-1-one;3-(4-(2-ethoxy-2-phenylethyl)-1-piperazinyl)-2-methyl-1-phenyl-1-propano ne
CBNumber
CB2103372
Molecular Formula
C24H32N2O2
Formula Weight
380.52
MOL File
10402-90-1.mol
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Eprazinone Property

Boiling point:
508.13°C (rough estimate)
Density 
1.0909 (rough estimate)
refractive index 
1.5500 (estimate)
storage temp. 
Sealed in dry,Room Temperature
pka
6.83±0.10(Predicted)
CAS DataBase Reference
10402-90-1(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
E588720
Product name
Eprazinone
Packaging
50mg
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
091181
Product name
3-(4-(2-Ethoxy-2-phenylethyl)piperazin-1-yl)-2-methyl-1-phenylpropan-1-one
Purity
95+%
Packaging
250mg
Price
$364
Updated
2021/12/16
Matrix Scientific
Product number
091181
Product name
3-(4-(2-Ethoxy-2-phenylethyl)piperazin-1-yl)-2-methyl-1-phenylpropan-1-one
Purity
95+%
Packaging
1g
Price
$807
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010468
Product name
1-(2-PHENYL-2-ETHOXY)ETHYL-4-(2-BENZOYL)PROPYLPIPERAZINE
Purity
95.00%
Packaging
1G
Price
$825.3
Updated
2021/12/16
Crysdot
Product number
CD33000598
Product name
Eprazinone
Purity
95+%
Packaging
25g
Price
$50
Updated
2021/12/16
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Eprazinone Chemical Properties,Usage,Production

Application

Epradone is mainly used clinically for coughs caused by acute and chronic bronchitis, pneumonia, asthma, and tuberculosis.

Originator

Mucitux,Riom,France,1969

Definition

ChEBI: A member of the class of piperazines in which the two amino hydrogens of piperazine are replaced by 2-benzoylpropyl and 2-ethoxy-2-phenylethyl groups.

Manufacturing Process

61.4 g of 0.2M of 1-(2-phenyl-2-ethoxy)piperazine dihydrochloride, 33.5 g (0.25M) propiophenone, 75 g (0.25M) trioxymethylene, 120 ml of ethanol and 0.4 ml of concentrated HCl are heated under reflux for 4 to 5 hours. The product is allowed to crystallize, then filtered and washed with alcohol. It is dried and recrystallized from methanol containing 10% H2O.
There is thus obtained 60 g of a white crystalline powder soluble in water. Yield: 66%. Melting point: 160°C.

Therapeutic Function

Antitussive

Eprazinone Preparation Products And Raw materials

Raw materials

Preparation Products

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Eprazinone Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9548
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Shanghai Licheng Chemical Co., Ltd.
Tel
021-67100011 15867680329
Fax
021-67105577
Email
1241713527@qq.com
Country
China
ProdList
75
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Wuhai Shuou Technology Co., Ltd.
Tel
17792809151
Fax
18872220797
Email
2355916837@ycphar.com
Country
China
ProdList
6133
Advantage
55
Wellman Pharmaceutical Group Limited
Tel
18971451745 18971451745
Fax
027-83991220
Email
15807197853@163.com
Country
China
ProdList
3630
Advantage
58
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View Lastest Price from Eprazinone manufacturers

Shaanxi Xianhe Biotech Co., Ltd
Product
Eprazinone 10402-90-1
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000kg
Release date
2025-05-07
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-[4-(β-ethoxyphenethyl)-1-piperazinyl]-2-methylpropiophenone dihydrochloride 10402-90-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-[4-(β-ethoxyphenethyl)-1-piperazinyl]-2-methylpropiophenone dihydrochloride 10402-90-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

10402-90-1, EprazinoneRelated Search:


  • EPRAZINONE
  • 1-(2-phenyl-2-ethoxy)ethyl-4-(2-benzoyl)propylpiperazine
  • β-[4-(β-Ethoxyphenethyl)-1-piperazinyl]-α-methylpropiophenone
  • 3-(4-(2-Ethoxy-2-phenylethyl)piperazin-1-yl)-2-Methyl-1-phenylpropan-1-one
  • 1-Propanone, 3-[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-
  • 1-(2-phenyl-2-ethoxyethyl)-4-(2-benzyloxypropyl)piperazine
  • 2-(4-(beta-ethoxyphenethyl)-1-piperazinyl)methyl-propiophenon
  • 3-(4-(2-ethoxy-2-phenylethyl)-1-piperazinyl)-2-methyl-1-phenyl-1-propano ne
  • 3-(4-(beta-ethoxyphenethyl)-1-piperazinyl)-2-methylpropiophenone
  • Eprazinone (base and/or unspecified salts)
  • Eprazinone USP/EP/BP
  • 3-[4-(β-ethoxyphenethyl)-1-piperazinyl]-2-methylpropiophenone dihydrochloride
  • 10402-90-1
  • 10402-53-9
  • C24H32N2O2